Olaparib Intermediate CAS 763114-26-7 Ịdị ọcha ≥98.5% Ụlọ ọrụ
Ịdị ọcha dị elu, mmepụta azụmahịa
Olaparib na ndị etiti emetụtara:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid CAS 763114-26-7
1- (Cyclopropylcarbonyl) piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
Aha Chemical | 2-Fluoro-5- ((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid. |
Ụdị okwu | 2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl] benzoic acid. |
Nọmba CAS | 763114-26-7 |
Nọmba CAT | RF-PI450 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C16H11FN2O3 |
Ibu molekụla | 298.27 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Yellow ruo Gbanyụọ-Ọcha ntụ ntụ |
Nyocha | ≥98.5% |
Mmiri (KF) | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.5% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Olaparib (CAS: 763113-22-0) |
ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid (CAS: 763114-26-7) bụ nke etiti eji na njikọ nke Olaparib (CAS: 763113-22). -0).Olaparib, nke AstraZeneca na-ere ahịa n'okpuru aha aha Lynparza, kwadoro na USA na December 2014 dị ka ezubere iche, otu ọgwụgwọ ọgwụgwọ maka ọgwụgwọ germline BRCA-mediated advanced ovarian cancer.Olaparib, nke KuDOS pharmaceuticals mepụtara na mgbe e mesịrị site AstraZeneca , Na-arụ ọrụ dị ka poly ADP ribose polymerase inhibitor ma kwadoro ya maka ndị ọrịa natara ọgwụgwọ atọ ma ọ bụ karịa nke chemotherapy.N'ime ule ụlọ ọgwụ, ọgwụ ahụ agbatịla ndụ na-enweghị ọganihu maka ndị ọrịa na-arịa ọrịa cancer ovarian na-emegharịghachi nke platinum.Olaparib nọkwa ugbu a na usoro nyocha dị iche iche maka ọgwụgwọ ara, afọ afọ, prostate, pancreatic na ọrịa kansa akpa ume na-abụghị obere cell.