4- (Methylsulfonyl) phenylacetic Acid CAS 90536-66-6 Ịdị ọcha> 99.5% (HPLC) Ụlọ ọrụ etiti Etoricoxib
Onye isi na-emepụta ihe na onye na-ebubata ya, ndị etiti nke Etoricoxib
Etoricoxib API CAS 202409-33-4
4- (Methylthio) Phenylacetic Acid CAS 16188-55-9
4- (Methylsulfonyl) Phenylacetic Acid CAS 90536-66-6
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Aha Chemical | 4- (Methylsulfonyl) phenylacetic acid |
Ụdị okwu | 4-Methylsulphonylphenylacetic acid;4- (Methanesulfonyl) phenylacetic acid;(4-Methanesulfonylphenyl) acetic acid;4-Methylsulfonyl Phenyl Acetic Acid;2- (4- (Methylsulfonyl) phenyl) acetic acid;[p- (Methylsulfonyl) phenyl] - Acetic Acid;4-Mesylphenylacetic acid |
Nọmba CAS | 90536-66-6 |
Nọmba CAT | RF-PI1182 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C9H10O4S |
Ibu molekụla | 214.24 |
Ebe Na-agbaze | 136.0 ruo 140.0 ℃ |
Njupụta | 1.35 |
Solubility | Soluble na methanol |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ụtụ siri ike na-acha ọcha ruo na-acha ọcha |
Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC) |
Ebe Na-agbaze | 136.0 ruo 140.0 ℃ |
Mmiri (KF) | <0.50% |
Otu adịghị ọcha Kachasịnụ | <0.30% |
Mgbakọta adịghị ọcha | <0.50% |
Spectrum infrared | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Etoricoxib (CAS: 202409-33-4) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
4-(Methylsulfonyl) phenylacetic Acid (CAS: 90536-66-6) bụ etiti nke Etoricoxib (CAS: 202409-33-4).Etoricoxib bụ ụdị cyclooxygenase-2 (COX-2) nke na-egbochi ihe mgbochi nke ụlọ ọrụ Merck mepụtara.A na-eji Etoricoxib eme ihe n'ọtụtụ ebe n'ịgwọ ọrịa ogbu na nkwonkwo (OA), ọrịa ogbu na nkwonkwo, ankylosing spondylitis, obere azụ mgbu na-adịghị ala ala, nnukwu ọrịa ogbu na nkwonkwo, isi dysmenorrhea na mgbu mgbe ịwachara ahụ, na ọrịa ndị ọzọ.Etoricoxib, onye na-emechi COX-2 ahọpụtara, nwere mgbochi mkpali, analgesic na antipyretic mmetụta, dabara maka ọgwụgwọ nke mgbaàmà na ihe ịrịba ama nke nnukwu na-adịghị ala ala osteoarthritis, yana nnukwu gouty ogbu na nkwonkwo.Etoricoxib na-etinye obi ngwa ngwa, yana bioavailability ọnụ nke 80 ruo 100%, wee rute mkpokọta plasma kachasị n'ime awa 1 ruo 2 ka emechara ya.Nri na-ebelata ọnụego nnabata mana ọ nweghị mmetụta na oke nnabata.Ọ na-egosipụta ogologo oge mkpochapụ ọkara ndụ ihe dị ka awa 22, na-egosipụta pharmacokinetics plasma linear na-enweghị mkpokọta n'oge ọtụtụ doses.