5-Aminosalicylic Acid CAS 89-57-6 (Mesalamine; 5-ASA) Ịdị ọcha> Ụlọ ọrụ 99.0% (HPLC)
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Aha Chemical | 5-Aminosalicylic acid |
Ụdị okwu | 5-Amino-2-Hydroxybenzoic Acid;Mesalamine;Mesalazine;5-ASA;5-AS;2-Hydroxy-5-Aminobenzoic Acid;3-Carboxy-4-Hydroxyaniline |
Nọmba CAS | 89-57-6 |
Nọmba CAT | RF2745 |
Ọnọdụ Ahịa | N'ahịa, Ikike Mmepụta Tọn 40 kwa ọnwa |
Usoro ihe omimi | C7H7NO3 |
Ibu molekụla | 153.14 |
Ebe Na-agbaze | 275.0 ~ 280.0 ℃ (dc.) (ọkụ) |
Njupụta | 1.3585 g/cm3 |
Mmetụta | Mmiri nwere mmetụta, ọkụ ọkụ, mmetụta ikuku |
Solubility na HCl | Ihe fọrọ nke nta ka ọ bụrụ nghọta |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ihe fọrọ nke nta ka ọ bụrụ ọcha ma ọ bụ isi awọ ma ọ bụ ntụ ntụ pink ma ọ bụ kristal |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
Ụzọ ịdị ọcha / nyocha | > 98.0% (Titration Nnọpụiche) |
Ebe Na-agbaze | 275.0 ~ 280.0 ℃ |
Ọnwụ na ihicha | <0.50% |
Ihe fọdụrụ na mgbanye | <0.20% |
Ọla dị arọ | <20ppm |
Mgbakọta adịghị ọcha | <1.00% |
Carbon-13 NMR Spectrum | Dabara na Ọdịdị |
Spectrum infrared | Dabara na Ọdịdị |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
Solubility na 1M HCl | Gafe |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ndị na-ahụ maka ọgwụ |
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5-Aminosalicylic Acid (Mesalazine, 5-ASA) (CAS: 89-57-6), monohydroxybenzoic acid bụ salicylic acid nke otu amino nọchiri anya na ọnọdụ 5.Nchacha, agba ntutu, mgbochi ọrịa cancer colorectal, ọgwụgwọ ọrịa afọ ọzịza, ọrịa autoimmune, mbufụt nke eriri afọ, ọrịa chemokine, ọrịa anụ ahụ mucosal, nsogbu ihi ụra, tenesmus rectoanal, ulcerative colitis.Mesalazine bụ ihe na-egbochi mkpali, na-ejikọta ya na salicylates, nke na-arụ ọrụ na ọrịa obi na-egbuke egbuke.A na-ewere ya dị ka ihe na-arụ ọrụ nke sulphasalazine.Nnyocha nke akụrụngwa ọgwụgwọ nke sulfasalazine na ndị mejupụtara ya [Mesalazine na Sulfapyridine] gosiri na mesalazine bụ akụrụngwa na-arụ ọrụ ọgwụgwọ, ebe sulfapyridine na-arụ ọrụ dị ka molekul na-ebu inert iji kwado nnyefe na colon.Nchọpụta a, tinyere mmetụta nke sulfapyridine n'ọtụtụ n'ime ihe ọjọọ ndị metụtara ọgwụgwọ sulfasalazine, mere ka mmepe nke Mesalazine dị ka usoro ọgwụgwọ dị ọcha.5-Aminosalicylic acid bụ ọgwụ na-ebute ụzọ, nke a na-eji agwọ ọrịa afọ mkpali dị ka ulcerative colitis (UC).Ọzọkwa, a na-eji ya eme ihe na-esiji esiji na akwụkwọ ndị na-emetụ ọkụ.