5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Onye na-emepụta ihe, ịdị ọcha dị elu, mmepụta azụmahịa
Dapagliflozin (CAS: 461432-26-8) Ndị na-emekọrịta ihe:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Aha Chemical | 5-Bromo-2-Chlorobenzoic Acid |
| Ụdị okwu | 2-Chloro-5-Bromobenzoic Acid |
| Nọmba CAS | 21739-92-4 |
| Nọmba CAT | RF-PI439 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C7H4BrClO2 |
| Ibu molekụla | 235.46 |
| Ebe Na-agbaze | 154.0 ruo 156.0 ℃ (ọkụ) |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Gbanyụọ-Ọcha ka ntụ ntụ edo edo dị ọkụ |
| Nyocha | ≥99.0% |
| Mmiri (KF) | ≤0.50% |
| Ihe fọdụrụ na mgbanye | ≤0.30% |
| 2-Chlorobenzoic acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Mgbakọta adịghị ọcha | ≤1.0% |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Dapagliflozin (CAS: 461432-26-8), ụdị ọrịa shuga II. |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
A na-eji 5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) dị ka ihe mmalite na njikọ nke Dapagliflozin (CAS: 461432-26-8), onye na-emechi sodium-glucose cotransporter-2 inhibitor nke na-ebelata akụrụ. A na-eji glucose reabsorption na-agwọ ndị ọrịa nwere ụdị ọrịa shuga II.Dapagliflozin bụ onye na-egbochi SGLT-2 (SLC5A2) nwere EC50 nke 1.1 nM.Ọ nwere ikike dị mma n'ofe mkpụrụ ndụ Caco-2 ma bụrụ mkpụrụ maka P-glycoprotein (P-gp).Dapagliflozin kwadoro na 2012 site na FDA.
