5-Methylisoxazole-4-Carboxylic Acid CAS 42831-50-5 Leflunomide Intermediate Ịdị ọcha>99.0% (HPLC)

Nkọwa dị mkpirikpi:

Aha Chemical: 5-Methylisoxazole-4-Carboxylic Acid

Ihe atụ: 5-Methyl-4-Isoxazolecarboxylic acid

Ọkụ: 42831-50-5

Dị ọcha:> 99.0% (HPLC)

Ntụ ntụ kristal na-acha ọcha ruo na-acha odo odo, enweghị isi

Ọkara nke Leflunomide (CAS: 75706-12-6)

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta 5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) nwere oke mma.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta 5-Methylisoxazole-4-Carboxylic Acid,Please contact: alvin@ruifuchem.com

Njirimara kemịkalụ:

Aha Chemical	5-Methylisoxazole-4-carboxylic acid
Ụdị okwu	5-Methyl-4-Isoxazolecarboxylic acid
adịghị ọcha	Leflunomide EP adịghị ọcha D/ Leflunomide BP adịghị ọcha D
Ọnọdụ Ahịa	N'ọkwa, Azụmahịa Azụmahịa
Nọmba CAS	42831-50-5
Usoro ihe omimi	C5H5NO3
Ibu molekụla	127.10 g / mol
Ebe Na-agbaze	145.0 ruo 149.0 ℃ (ọkụ)
Njupụta	1.348±0.06 g/cm3
Okpomọkụ nchekwa.	Ebe dị jụụ na nkụ (2 ~ 8 ℃)
COA & MSDS	Dị
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Ụkpụrụ nyocha	Nsonaazụ
Ọdịdị	Ntụ ntụ kristal na-acha ọcha ruo na-acha odo odo, enweghị isi	Na-akwado
Ebe Na-agbaze	145.0 ruo 149.0 ℃	147.8-148.5 ℃
Ọnwụ na ihicha	≤0.50%	0.13%
Ihe fọdụrụ na mgbanye	≤0.10%	0.04%
Ọla dị arọ (Pb)	≤0.002%	<0.002%
3-Methyl Isomeric Compound	≤0.20%	<0.20%
Ụzọ ịdị ọcha / nyocha	> 99.0% (HPLC)	99.74%
Spectrum infrared	Dabara na Ọdịdị	Na-akwado
1 H NMR Spectrum	Dabara na Ọdịdị	Na-akwado
Mmechi	A nwalela ngwaahịa a wee kwado nkọwa ndị enyere
Na-eji	Ndị na-ahụ maka ọgwụ nke Leflunomide (CAS: 75706-12-6)

Ngwugwu/Nkwakọba/Mbupu:

ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mechiri emechi.Chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe ikuku na-ekupụ nke ọma pụọ na ihe ndị na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.

Uru:

Ike zuru oke: akụrụngwa na ndị ọrụ nka zuru oke

Ọrụ Ọkachamara: Otu nkwụsị ịzụrụ ọrụ

Ihe ngwugwu OEM: ngwugwu omenala na akara dị

Nnyefe ngwa ngwa: Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ

Nkwanye kwụsiri ike: Jikwaa ngwaahịa ezi uche dị na ya

Nkwado nka na ụzụ: Ngwọta teknụzụ dị

Ọrụ Synthesis Custom: sitere na gram ruo kilos

Ogo dị elu: guzobe usoro mmesi obi ike zuru oke

Ajụjụ:

Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.

Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.

Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.

OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.

Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.

Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.

MOQ?Enweghị MOQ.A na-anabata obere usoro.

Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.

Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.

Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.

Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.

Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.

42831-50-5 - Ihe ize ndụ na nchekwa:

Koodu ihe egwu
R36 / 37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
R37 / 38 - na-akpasu iwe na usoro iku ume na akpụkpọ ahụ.
R36 - na-akpasu iwe na anya
R10 - ọkụ
Nkọwapụta nchekwa
S22 - Ekula uzuzu.
S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36/37/39 - Yiri uwe nchebe kwesịrị ekwesị, uwe aka na nchebe anya / ihu.
S36 - Yiri uwe nchebe kwesịrị ekwesị.
S16 - Wepụ ya na isi mmalite nke mgbanye.
WGK Germany 3
Koodu mpaghara:: 2917399090
Klas ihe egwu IGBO

Ngwa:

5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) bụ n'etiti maka njikọ nke Leflunomide (CAS: 75706-12-6).Leflunomide bụ ụdị ọgwụ isoxazole immunosuppressive nke nwere ọrụ mgbochi proliferative, ọgwụ ọgbara ọhụrụ na-ekewa ngwaahịa a dị ka ọgwụ antipyretic, analgesic na mgbochi mkpali.Ngwaahịa a nwere ike gbanwee ngwa ngwa na metabolites na-arụ ọrụ ma na-arụ ọrụ site na imeju na cytoplasm intestinal na microsomes, ya;Isi usoro bụ n'oge DNA njikọ, na-egbochi a isi enzyme-DHODH (DHODH) ọrụ, nke mere na nucleotides n'ime B lymphocyte na-agwụ agwụ, na-ejedebe na biosynthesis nke DNA na RNA, mkpụrụ ndụ enweghị ike ịbanye s na-adọ, na n'ikpeazụ enweghị ike ịbanye s oge. na-agbasawanye, na-akpata mmetụta mgbochi-rheumatic, ọ dị mma maka ọgwụgwọ ndị okenye na-arịa ọrịa ogbu na nkwonkwo na-arụ ọrụ, ankylosing spondylitis, ọ nwere ike belata mbibi ọkpụkpụ, belata mgbaàmà na ihe ịrịba ama.Tụkwasị na nke ahụ, leflunomide nwekwara ike igbochi ọrụ tyrosine kinase, si otú ahụ na-egbochi mgbasa nke T cell, B cell na sel ndị na-adịghị egbochi ya, ma ọ nwekwara ike, site na biosynthesis inhibition nke cyclooxygenase-2 (COX2), na-egbochi njikọ prostaglandin ma na-eme ihe mgbochi. mmetụta mkpali na igbochi mast sel na basophils histamine ntọhapụ.Mgbe a na-eji ngwaahịa a na ndị ọrịa na-ebugharị akụkụ ahụ, mmezi dose ahụ siri ike, a na-ejikarị agwọ ọrịa ogbu na nkwonkwo na ọrịa autoimmune ndị ọzọ.