6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Nyefee na ịdị ọcha dị elu, mmepụta azụmahịa
Aha Chemical: 6-O-Methylguanine
Ọnọdụ: 20535-83-5
| Aha Chemical | 6-O-Methylguanine |
| Ụdị okwu | 2-Amino-6-Methoxypurine |
| Nọmba CAS | 20535-83-5 |
| Nọmba CAT | RF-PI509 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C6H7N5O |
| Ibu molekụla | 165.16 |
| Ebe Na-agbaze | > 300 ℃ (ọkụ) |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Gbanyụọ-White Crystalline ntụ ntụ |
| Usoro nyocha / nyocha | ≥98.5% (HPLC) |
| Ọnwụ na ihicha | ≤0.50% |
| Ihe fọdụrụ na mgbanye | ≤0.50% |
| Mgbakọta adịghị ọcha | ≤1.5% |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Enwere ike iji 6-O-Methylguanine (CAS: 20535-83-5) mee ihe dị ka etiti na njikọ nke Nelzarabine (CAS: 121032-29-9).Nelarabine bụ prodrug maka deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates na ọrụ nke adenosine deaminase (ADA) wee ghọọ ara-G.GlaxoSmithKline mepụtara Nelarabine nke ọma.Na October 28, 2005 n'okpuru nkwado nke US Food and Drug Administration, ọ ghọrọ ọgwụ ọhụrụ maka ọgwụgwọ T-cell nnukwu lymphoblastic leukemia (T-ALL) na T-cells lymphoblasticlymphoma (T-LBL) nke na-eguzogide ma ọ dịkarịa ala. ụdị abụọ nke usoro ọgwụgwọ chemotherapy ma ọ bụ nlọghachi azụ mgbe ọgwụgwọ mbụ gasịrị.Edepụtara ọgwụ ọhụrụ a na United States na 2006.
