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7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3 Tolvaptan Intermediate egosipụtara
  • 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3 Tolvaptan Intermediate

7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3 Tolvaptan Intermediate

Nkọwa dị mkpirikpi:

Aha: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu

Ọkụ: 160129-45-3

Dị ọcha: ≥99.0% (HPLC)

Ọdịdị: Ìhè Green ka Ìhè Yellow Powder

Ọkara nke Tolvaptan (CAS 150683-30-0) maka ọgwụgwọ Hyponatremia.

Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com

 


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Nbunye onye nrụpụta, ogo dị elu, nrụpụta azụmaahịa
Tolvaptan na ndị etiti emetụtara:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5

Njirimara kemịkalụ:

Aha Chemical 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu
Ụdị okwu 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-otu;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-otu
Nọmba CAS 160129-45-3
Nọmba CAT RF-PI395
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C10H10ClNO
Ibu molekụla 195.65
Ebe Na-agbaze 103.0 ruo 107.0 ℃
Solubility Soluble na methanol
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ìhè akwụkwọ ndụ akwụkwọ ndụ ka ọ bụrụ ntụ ntụ edo edo
Ụzọ njirimara NMR, HPLC
Ụzọ ịdị ọcha / nyocha ≥99.0% (HPLC)
Ọnwụ na ihicha ≤1.0%
Ihe fọdụrụ na mgbanye ≤0.50%
Ọdịghị ọcha ọ bụla ≤0.50%
Mgbakọta adịghị ọcha ≤1.0%
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ihe dị n'etiti Tolvaptan (CAS 150683-30-0), ọgwụgwọ nke Hyponatremia

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

1

Ajụjụ:

Ngwa:

7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu (CAS 160129-45-3) bụ ihe etiti na njikọ nke Tolvaptan (CAS 150683-30-0).Tolvaptan bụ onye na-ahọrọ, asọmpi ọnụ na-adịghị arụ ọrụ nke arginine vasopressin V2 antagonist nwere IC50 nke 1.28µM maka mgbochi nke nchịkọta platelet na-ebute AVP.A na-eji Tolvaptan agwọ ọrịa hyponatremia metụtara nkụchi obi, cirrhosis, na ọrịa nke homonụ antidiuretic na-ekwesịghị ekwesị.Tolvaptan nọkwa na nnwale ụlọọgwụ maka ọrịa akụrụ polycystic.Ọgwụgwọ na Tolvaptan na-ebute mbelata ịdị arọ nke anụ ahụ ngwa ngwa na nke kwụgidere n'otu oge na mmụba nke mmepụta mmamịrị, na-emeziwanye na/ma ọ bụ na-emezi sodium serum n'ime ndị ọrịa hyponatremic, na-ebelata akara na mgbaàmà nke mkpọchị ma na-abawanye akpịrị ịkpọ nkụ.

Dee ozi gị ebe a ziga anyị ya