7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity
Aha Chemical | 7-Ethyl-10-Hydroxycamptothecin |
Ụdị okwu | SN-38 |
Nọmba CAS | 86639-52-3 |
Nọmba CAT | RF-PI242 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C22H20N2O5 |
Ibu molekụla | 392.41 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha odo odo na-acha odo odo |
njirimara (IR, UV) | (1) Ultraviolet ray absorption ụdịdị dị iche iche kwekọrọ na ihe ndị a chọrọ (2) Infrared ray absorption spectrum concordant nwere ọkọlọtọ ọkọlọtọ spectrum ga-agbaso n'ule akwadoro. |
Ebe Na-agbaze | 228.0 ~ 235.0 ℃ |
Ihe ndị emetụtara | ≤1.5% |
10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Oke adịghị ọcha amabeghị | ≤0.50% |
Ọnwụ na ihicha | ≤1.0% |
Ọla dị arọ | ≤10ppm |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Ngwọta doo anya | Kpochapụ |
Nyocha | ≥98.0% (HPLC) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Onye na-ahụ maka ọgwụ nke Irinotecan |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.
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Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na onye na-ebubata 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) na oke mma.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) bụ metabolite na-arụ ọrụ nke Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) na-egbochi DNA na njikọ RNA na IC50s nke 0.077 na 1.3 μM, n'otu n'otu.7-Ethyl-10-Hydroxycamptothecin (SN-38), bụ metabolite na-arụ ọrụ nke Irinotecan, ihe nrụpụta semisynthetic nke camptothecin, alkaloid nke quinoline dị na ogbugbo nke osisi camptotheca China na osisi nothapodytes Asia.Ọ bụ ezie na 7-Ethyl-10-Hydroxycamptothecin nwere ike ruru 1,000 ugboro karịa Irinotecan, a gbanwebeghị ya ka ọ bụrụ onye na-achọ ọgwụ ike n'ihi na ọ naghị edozi ya.A na-anwale ule ụlọ ọgwụ ugbu a yana akụkụ ndị ọzọ nke nwere ike mee ka ọ dị irè dị ka ọgwụ antineoplastic.