Afatinib Dimaleate Intermediate CAS 314771-88-5 Ịdị Ọcha>99.0% (HPLC) Foto egosipụtara

Afatinib Dimaleate Intermediate CAS 314771-88-5 Ịdị ọcha> Ụlọ ọrụ 99.0% (HPLC)

Nkọwa dị mkpirikpi:

Aha Chemical: (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine

Nọmba: 314771-88-5

Dị ọcha:> 99.0% (HPLC)

Ọdịdị: Yellow to Light Yellow Powder

Nke etiti Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Nkọwa:

Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -otu CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S) -N4- (3-Chloro-4-Fluorophenyl) -7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-AmineCAS 314771-88-5

Njirimara kemịkalụ:

Aha Chemical	(S)-N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-Amine
Ụdị okwu	N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-[(3S) -oxolan-3-yl] oxyquinazolin-4-Amine;7-((S) -Tetrahydrofuran-3-yloxy) -4- (3-Chloro-4-Fluorophenyl) amino-6-Nitroquinazoline;Afatinib adịghị ọcha
Nọmba CAS	314771-88-5
Nọmba CAT	RF-PI2027
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C18H14ClFN4O4
Ibu molekụla	404.78
Njupụta	1.534±0.060 g/cm3
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ntụ ntụ edo edo na-acha odo odo
Ụzọ ịdị ọcha / nyocha	> 99.0% (HPLC)
Ọnwụ na ihicha	<0.50%
Ọdịghị ọcha nke Onwe Onye	<0.50%
Mgbakọta adịghị ọcha	<1.00%
Ọla dị arọ	≤20ppm
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Nke etiti Afatinib Dimaleate (CAS: 850140-73-7)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

Ngwa:

(S) -N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-Amine (CAS: 314771-88-5) na-eji na nkwadebe nke Afatinib Dimaleate (CAS: 850140-73-7).Afatinib bụ ọgwụ ọhụrụ e lekwasịrị anya maka ọrịa kansa, ọgbọ ọhụrụ nke ọgwụ e lekwasịrị anya ọnụ, ọgwụ e lekwasịrị anya maka ọrịa kansa n'ụwa nke na-ejikọ ezinụlọ ErbB n'ụzọ na-adịghị agbanwe agbanwe, ma dịkwa irè na nke ezubere iche na-egbochi mgbaàmà nke na-ebute uto mkpụrụ ndụ kansa. , ibelata ma ọ bụ na-egbu oge mmụba nke mkpụrụ ndụ kansa.Afatinib bụ nke otu ọgwụ a maara dị ka ihe mgbochi tyrosine kinase.Ọ na-arụ ọrụ site na igbochi ọrụ nke protein abụọ nwere njikọ chiri anya, onye na-anabata ihe na-eto eto na-eto eto (EGFR) na onye na-anabata ihe na-eto eto nke mmadụ 2 (HER2).A na-eji ya maka ọgwụgwọ ahịrị mbụ nke ndị ọrịa nwere ọrịa kansa akwara metastatic na-abụghị obere cell.Afatinib bụ ọgwụ ọhụrụ e lekwasịrị anya maka ọrịa kansa, ọgbọ ọhụrụ nke ọgwụ e lekwasịrị anya ọnụ, ọgwụ e lekwasịrị anya maka ọrịa kansa n'ụwa nke na-ejikọ ezinụlọ ErbB n'ụzọ na-adịghị agbanwe agbanwe, ma dịkwa irè na nke ezubere iche na-egbochi mgbaàmà nke na-ebute uto mkpụrụ ndụ kansa. , ibelata ma ọ bụ na-egbu oge mmụba nke mkpụrụ ndụ kansa.