Anastrozole CAS 120511-73-1 API Factory High Quality

Anastrozole (CAS 120511-73-1), bụ ihe na-abụghị steroidal, ọgbọ atọ achiral triazole ewepụtara dị ka ARIMIDEX® site AstraZeneca Pharmaceuticals LP1.Ọ bụ otu n'ime ọgbọ nke atọ nke aromatase inhibitor bụ onye na-asọmpi na-ahọrọ nke ọma nke aromatase, si otú a na-egbochi ntụgharị nke testosterone n'ime estradiol na androstenedione n'ime estrone.Mgbochi nke enzyme aromatase na-apụta karịsịa site na njigide aromatase na hemegroup nke cytochrome P450, na-ebelata estrogen biosynthesis n'ime anụ ahụ dị n'akụkụ anụ ahụ na n'ime ara.

Anastrozole bụ ọgwụgwọ a na-anabatakarị nke ọma maka ọrịa kansa ara.Dị ka ndị ọzọ na-emechi aromatase, mmetụta ọjọọ ya kachasị mkpa bụ ihe ize ndụ dị ukwuu nke ọkpụkpụ ọkpụkpụ, nke maka anastrozole bụ nanị oge ọgwụgwọ.Ọ nwere njirimara dị nro ma e jiri ya tụnyere chemotherapy;Otú ọ dị, a chọpụtala na ọtụtụ ndị ọrịa na-agwọ ọrịa anastrozole emeela mkpesa maka mgbaàmà nkwonkwo karịa ka a tụrụ anya ya, karịsịa isi ike dijitalụ yiri nke ọrịa ogbu na nkwonkwo.Ụfọdụ ule ụlọ ọgwụ nke anastrozole maka ụmụ nwanyị postmenopausal nwere ọrịa ara ara na Europe na United States kọrọ ọrịa musculoskeletal dị ka ihe ọjọọ.Anastrozole (Arimidex®) bụ ihe mgbochi aromatase nke akwadoro na EU, US na mba ndị ọzọ n'ụwa niile maka iji ya mee ihe dị ka ọgwụgwọ adjuvant na ụmụ nwanyị postmenopausal nwere mmalite mmalite, hormone receptor-positive cancer cancer.A kwadoro ya na EU na mba ndị ọzọ n'ụwa nile maka ịga n'ihu na ọgwụgwọ adjuvant na ụmụ nwanyị ndị nweburu afọ 2-3 nke ọgwụgwọ adjuvant tamoxifen maka ọrịa kansa ara.