Argatroban CAS 74863-84-6 API Ụlọ ọrụ na-eme ka ọ ghara ịdị ọcha
Ndị nrụpụta Argatroban emetụtara ndị nrụpụta:
Ethyl (2R,4R) -4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
| Aha Chemical | Argatroban |
| Ụdị okwu | Argatroban anhydrous |
| Nọmba CAS | 74863-84-6 |
| Nọmba CAT | RF-API67 |
| Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
| Usoro ihe omimi | C23H36N6O5S |
| Ibu molekụla | 508.63 |
| Ebe Na-agbaze | 188.0-189.0 ℃ |
| Ebe esi nri | 801.3ºC na 760 mmHg |
| Njupụta | 1.47 g/cm3 |
| Ọnọdụ mbupu | Ebugara n'okpuru okpomọkụ gburugburu |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
| njirimara HPLC | Ogologo oge njide nke ụkpụrụ nke enwetara site na ngwọta nnwale kwekọrọ na nke enwetara na Standard Solution, dị ka ule na Assay |
| njirimara IR | Dakọtara na IR Spectrum nke AG RS |
| njirimara UV | Na 259nm na 332nm wavelength ebe kwesịrị inwe kacha absorption |
| Mmiri | 2.5-4.5% |
| Agba ngwọta & doo anya | Ngwọta kwesịrị ịdị ọcha agba |
| Mekọrịta ihe | |
| adịghị ọcha A + adịghị ọcha H | ≤0.10% |
| adịghị ọcha B | ≤0.10% |
| adịghị ọcha C + adịghị ọcha E | ≤0.10% |
| adịghị ọcha D | ≤0.10% |
| adịghị ọcha I | ≤0.10% |
| Bach nke adịghị ọcha akọwapụtaghị | ≤0.10% |
| Mgbakọta adịghị ọcha | ≤0.30% |
| Ihe mgbaze fọdụrụnụ | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl acetate | ≤5000ppm |
| Enantiomer (HPLC) | ≤0.10% |
| Ọnụego Isomer (HPLC) | 30.0% -40.0% |
| Chloride | ≤0.01% |
| Ihe fọdụrụ na mgbanye | ≤0.10% |
| Ọla dị arọ | ≤10ppm |
| Endotoxins nke nje bacteria | <5EU/mg |
| Oke Microbial | TAMC ≤1000 cfu/g |
| Nyocha | 98.0% -102.0% (na-adabere na mmiri ọkụ) |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API, Sịntetic Antithrombotic Agent Anticoagulant |
ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-eweta Argatroban (CAS: 74863-84-6) nwere àgwà dị elu, API.
Argatroban (CAS: 74863-84-6) bụ ihe ọhụrụ sịntetik antithrombotic ihe bara uru na mmezi anticoagulation ha ischemic ọrịa strok na-ekesa intravascular coagulation.Ọ bụ anticoagulant nke bụ obere molekul kpọmkwem thrombin inhibitor.N'afọ 2000, a na-enye argatroban ikike site na nchịkwa nri na ọgwụ ọjọọ (FDA) maka mgbochi ma ọ bụ ọgwụgwọ thrombosis na ndị ọrịa nwere heparin-induced thrombocytopenia (HIT).N'afọ 2002, a kwadoro ya maka iji ya mee ihe n'oge a na-eme ihe gbasara akwara obi na ndị ọrịa nwere HIT ma ọ bụ nọ n'ihe ize ndụ maka ịmepụta ya.N'afọ 2012, MHRA kwadoro ya na UK maka ọgwụ mgbochi ọrịa na ndị ọrịa nwere heparin-induced thrombocytopenia Ụdị II (HIT) nke chọrọ ọgwụgwọ antithrombotic parenteral.
