Aripiprazole Intermediate CAS 129722-34-5 Ịdị ọcha>98.0% (HPLC)
Ndị nrụpụta na-eweta etiti nke Aripiprazole na ịdị ọcha dị elu
Aripiprazole API CAS 129722-12-9
1- (2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H) -Quinolinone CAS 22246-18-0
7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone CAS 129722-34-5
| Aha Chemical | 7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone |
| Ụdị okwu | 7- (4-Bromobutoxy) -3,4-Dihydroquinolin-2 (1H) -otu;7- (4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7- (4-Bromobutoxy) -2 (1H) -Quinolinone;Aripiprazole adịghị ọcha 3 |
| Nọmba CAS | 129722-34-5 |
| Nọmba CAT | RF-PI2269 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C13H16BrNO2 |
| Ibu molekụla | 298.18 |
| Njupụta | 1.383 g/cm3 |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Crystal ntụ ntụ na-acha ọcha ma ọ bụ na-acha odo odo |
| Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) |
| Ebe Na-agbaze | 110.0 ~ 114.0 ℃ |
| Ọnwụ na ihicha | <1.00% |
| Ihe fọdụrụ na mgbanye | <0.50% |
| Ọla dị arọ (dị ka Pb) | ≤20ppm |
| Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Aripiprazole (CAS: 129722-12-9) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone (CAS: 129722-34-5) bụ etiti na njikọ nke Aripiprazole (CAS: 129722-12-9).Ngwaahịa na-emebi emebi na mbadamba Aripiprazole.Aripiprazole (Abilify).Kacha ọhụrụ, longactingaripiprazole (ihe arylpiperazine quinolinone derivative), na-egosi na ọ bụ agonist nke ndị na-anabata D2 (ya bụ, na-akpali ụfọdụ ndị na-anabata D2 mgbe ọ na-egbochi ndị ọzọ dabere na ebe ha nọ na ụbụrụ yana ntinye ọgwụ).Bioavailability nke Aripiprazole dị ihe dịka 87%, yana mmụba kachasị elu na plasma na-enweta n'ime awa 3 ruo 5 ka emechara ya.A na-emezi ya site na dehydrogenation, oxidative hydroxylation, na N-dealkylation, nke ukwuu site na imeju CYPs 3A4 na 2D6.Maka ọgwụgwọ nke schizophrenia na nsogbu uche nke metụtara ya.Onye na-emegide onye na-anabata dopamine D2 nwere ọrụ agonist autoreceptor dopamine.Antipsychotic.
