Atazanavir CAS 198904-31-3 Ịdị Ọcha ≥99.0% API Ụlọ ọrụ Anti-HIV HIV-1 Protease Inhibitor
Nye ya na ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Atazanavir
OZI: 198904-31-3
Onye na-egbochi nje HIV-1
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Atazanavir |
Ụdị okwu | BMS-232632 |
Nọmba CAS | 198904-31-3 |
Nọmba CAT | RF-API70 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
Usoro ihe omimi | C38H52N6O7 |
Ibu molekụla | 704.86 |
Ebe Na-agbaze | 207.0-209.0 ℃ |
Solubility | Soluble na DMSO;Na-adịghị edozi n'ime mmiri |
Nchekwa ogologo oge | Na-echekwa ogologo oge na -20 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ntụ ntụ |
Ụdị | Ebe efu |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
adịghị ọcha A | ≤0.10% |
adịghị ọcha B | ≤0.10% |
Otu adịghị ọcha | ≤0.20% |
Mgbakọta adịghị ọcha | ≤1.0% |
Ụzọ ịdị ọcha/nyocha | ≥99.0% (HPLC) |
pH | 5.0-8.0 |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | HIV-1 Protease Inhibitor Anti-HIV |
ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
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Atazanavir (CAS 198904-31-3) bụ ọgwụ mgbochi retroviral, akwụkwọ ọgụgụ na ọgwụ azapeptide siri ike nke klaasị protease inhibitor (PI).A na-ere ya n'okpuru aha ahia Reyataz.Dị ka antiretrovirals ndị ọzọ, a na-eji ya agwọ ọrịa nke ụdị nje immunodeficiency mmadụ 1 (HIV-1) protease enzyme na mgbochi mgbe niile Ki of 66 nmol/L ma na-egbochi nje nje HIV-1 na 50% irè itinye uche EC50 sitere na si. 2.6 ruo 5.3 nmol/l.Atazanavir na-ejikọta na nje HIV-1 protease na-egbochi nkwụsị nke gag na gag-pol polyproteins, nke na-eme ka e guzobe virions na-eto eto na mkpụrụ ndụ nje HIV-1.Atazanavir nwere usoro kemịkalụ symmetric C-2 dị iche na ikike mgbochi nje HIV dị iche iche ma e jiri ya tụnyere ndị na-egbochi protease ndị ọzọ, gụnyere Indinavir, Nelfinavir, Ritonavir, Saquinavir na Amprenavir.Atazanavir dị iche na PI ndị ọzọ n'ihi na enwere ike inye ya otu ugboro kwa ụbọchị ma nwee mmetụta dị nta na profaịlụ lipid nke onye ọrịa.Dị ka ndị ọzọ na-egbochi protease, a na-eji ya na ọgwụ nje HIV ndị ọzọ na-ejikọta ya.Atazanavir bụ akwụkwọ akụkọ azapeptide HIV protease inhibitor.Antiviral.A na-ewere ya n'ọnụ otu ugboro n'ụbọchị.
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