Azilsartan CAS 147403-03-0 Ịdị ọcha> 99.5% (HPLC) ụlọ ọrụ API
Onye na-emepụta ihe, ịdị ọcha dị elu, mmepụta azụmahịa
Aha Chemical | Azilsartan |
Ụdị okwu | 2-Ethoxy-1-[[2'- (4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl] methyl] benzimidazole-7-Carboxylic Acid |
Nọmba CAS | 147403-03-0 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C25H20N4O5 |
Ibu molekụla | 456.46 |
Ebe Na-agbaze | 188 ℃ (Dec.) |
Njupụta | 1.42 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ |
njirimara | Dakọtara na ọkọlọtọ ntụaka |
Solubility | Na-adịghị edozi ya na mmiri, Na-agbaze ntakịrị na Ethanol |
Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC) |
Ọnwụ na ihicha | <0.50% |
Ihe fọdụrụ na mgbanye | <0.20% |
Ọla dị arọ | <10ppm |
Ihe ndị emetụtara | |
adịghị ọcha A | <0.15% |
adịghị ọcha B | <0.10% |
adịghị ọcha C | <0.10% |
Ndị ọzọ na-amaghị ihe kacha otu adịghị ọcha | <0.10% |
Mgbakọta adịghị ọcha | <0.50% |
Ihe mgbaze fọdụrụnụ | |
Dichloromethane | <0.06% |
Acetone | <0.50% |
Ethyl acetate | <0.50% |
Methanol | <0.30% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Azilsartan (CAS: 147403-03-0) bụ ọgwụ angiotensin II antagonist nke na-emepe emepe maka ọgwụgwọ ọbara mgbali elu, nke a na-ejikarị maka ọgwụgwọ ọbara mgbali elu.Ọ bụkwa naanị ọgwụ angiotensin II nnabata antagonist (sartan class) ọgwụ na ọkwa ụlọ ọgwụ dị elu ugbu a.A na-eji ngwakọta Azilsartan na Chlorthalidone na-agwọ ọbara mgbali elu (ọbara mgbali elu).Azilsartan bụ angiotensin II receptor blocker (ARB).Ọ na-arụ ọrụ site na igbochi ihe dị n'ime ahụ nke na-eme ka arịa ọbara sie ike.N'ihi ya, azilsartan na-eme ka arịa ọbara dị jụụ.Nke a na-ebelata ọbara mgbali ma na-ebuwanye ibu nke ọbara na oxygen na obi.A kwadoro Azilsartan ma malite na Japan maka ọgwụgwọ ọbara mgbali elu na May 2012. Azilsartan, nke a na-ere ahịa n'okpuru aha ahia Azilva.