Betulin CAS 473-98-3 Ịdị Ọcha> 99.0% (HPLC) Mwepụta Osisi
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta Betulin (CAS: 473-98-3) nwere àgwà dị elu.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Betulin,Please contact: alvin@ruifuchem.com
Aha Chemical | Betulin |
Ụdị okwu | Betulinol;Mmanya Betulinic;Betula Camphor;Akpụkpọ anụ Birch;Betulol;Trochol;Lup-20 (29) -ene-3β,28-diol;(3β) -Lup-20 (29) -ene-3,28-diol |
Ọnọdụ Ahịa | N'ahịa, arụpụtara na azụmaahịa |
Nọmba CAS | 473-98-3 |
Usoro ihe omimi | C30H50O2 |
Ibu molekụla | 442.73 g/mol |
Ebe Na-agbaze | 251.0 ~ 257.0 ℃ |
Njupụta | 1.017g / cm3 |
Ntụgharị a kapịrị ọnụ [a]20/D | +17.0° ruo +21.0° (C=2 na Pyridine) |
Nkwụsi ike | Hygroscopic |
Okpomọkụ nchekwa. | Ebe dị jụụ na nkụ (2 ~ 8 ℃) |
COA & MSDS | Dị |
Otu | Ihe ọkụkụ |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ | Ọcha ntụ ntụ |
Betulin ịdị ọcha | > 98.0% (HPLC) | 99.15% |
Ebe Na-agbaze | 251.0 ~ 257.0 ℃ | Na-akwado |
Ọnwụ na ihicha | <2.00% (2g/105 ℃ / awa 5) | 0.13% |
Ash | <0.50% (2g/600 ℃ / awa 5) | 0.10% |
Njupụta nnukwu | 0,25 ~ 0,45 g / ml | Na-akwado |
Nha urughuru | 98% gafere 80 Mesh | Na-akwado |
Ọla dị arọ (Pb) | ≤10ppm | <10ppm |
Arsenic (dị ka) | ≤1pm | <1pm |
Ihe mgbaze fọdụrụnụ | ≤1000ppm | Na-akwado |
Nnwale Microbiological | ||
Ngụkọta ọnụ ọgụgụ efere | ≤1000CFU/g | Na-akwado |
Yist & ebu | ≤100CFU/g | Na-akwado |
Escherichia Coli | Ihe ọjọọ | Ihe ọjọọ |
Spectrum infrared | Dabara na Ọdịdị | Na-akwado |
Solubility na Pyridine 50mg / ml | Yellow ruo Brown doro anya ruo ntakịrị uzuzu | Gafe |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwapụta |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mechiri emechi.Chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe ikuku na-ekupụ nke ọma pụọ na ihe ndị na-ekwekọghị ekwekọ.Chebe ọkụ na mmiri na oke okpomọkụ.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
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Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
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Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
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Betulin (CAS: 473-98-3) bụ ihe ewepụtara site na ogbugbo osisi birch ọcha, nke amara kemgbe narị afọ nke 18 ma kọwaa ya na kemịkalụ.Onye German-Russian chemist Johann Tobias Lowitz chọtara Betulin.Ọ bụ onye ọkà mmụta sayensị mbụ nyochara ma kọwaa betulin, na ime ya bụ otu n'ime ndị mbụ wepụrụ ihe ọkụkụ na-arụ ọrụ.Betulin bụ ihe sitere na ahịhịa dị ọcha nke na-enye ogbugbo birch agba ọcha ya.Betulin na-echebe osisi birch pụọ na mmetụta gburugburu ebe obibi, dị ka oke okpomọkụ, ọrịa nje na ụzarị anyanwụ.
Betulin bụ ọcha crystalline ntụ ntụ, soluble na mmanya, chloroform na benzene, ubé soluble na mmiri oyi, petroleum ether.
Mmetụta physiological nke betulin
1. Betulin na usoro ya egosila nnukwu ikike dị ka ndị na-ahụ maka nje na nje HIV na ọgwụgwọ ọrịa kansa.Ha na-arụ ọrụ site na itinye aka na njedebe nke usoro ndụ nje virus na-ejikọta ya na ntinye nje na uto na maturation.
2. Ọgwụ mgbochi tumor dị irè, nke na-eme ka ụfọdụ ụdị mkpụrụ ndụ tumo na-amalite mmemme apoptosis na-ebibi onwe ya, ma nwee ike belata uto nke ụdị mkpụrụ ndụ dị iche iche.
3. Betulin nwere ike ibelata oke ibu nri na-akpata, belata ọdịnaya lipid na serum na anụ ahụ, ma melite mmetụta in-sulin k.
4. Ha nwere ihe ndị na-egbochi mkparị dị nro na mkpokọta dị elu, na ihe ndị na-egbochi mkpali ha bụ n'ihi nkwụsị nke ụzọ mkpụrụ ndụ na-abụghị akwara.
5. Betulin nwere ike igbochi maturation nke sterol regulatory regulatory element-binding proteins (SBERPs) na vivo, si otú ibelata biosynthesis nke cholesterol na ọdụdụ asịd.
6. Tụkwasị na nke ahụ, Betulin nwere mgbochi mkpali, mgbochi nje, na-egbochi mgbasa nke protein na eriri ntutu, na-eme ka ntutu dị mma na-egbuke egbuke, na-akwalite uto ntutu.Enwere ike iji Betulin na nri, ihe ịchọ mma na ụlọ ọrụ ọgwụ.
Ụlọ ọrụ ọgwụ:
A na-ejikarị Betulin eme ihe dị ka onye na-ahụ maka ọgwụ, na Betulin na ihe ndị na-emepụta ya dị ka ndị na-ahụ maka ihe ndị dị ndụ egosila nnukwu ikike n'ịgwọ nje HIV na ọrịa cancer.N'otu oge ahụ, a na-eji ya maka antitussive na expectorant, ọgwụgwọ nke rhinitis nfụkasị, ehighi ura, ịda mbà n'obi, wdg.
Ụlọ ọrụ nri:
Enwere ọmụmụ ihe na-eji ya dị ka ihe nchekwa na ngwaahịa anụ.
Ụlọ ọrụ ịchọ mma:
Mmetụta mgbochi nke Betulin na ọrụ collagenase na mmụba nke mkpụrụ ndụ akpụkpọ ahụ na-egosi na ọ nwere mmetụta siri ike na-egbochi ịka nká na enwere ike iji mee ka akpụkpọ ahụ dịkwuo mma, mee ka akpụkpọ ahụ dịkwuo mma, ma gbochie akpụkpọ ahụ gbawara agbawa.Ọ bụkwa ezigbo enyemaka ntinye n'èzí.
Ugbu a, a na-enweta Betulin tumadi site na mmịpụta ozugbo, yana tumadi site na mmịpụta reflux reflux na recrystallization ọcha Kpọmkwem: 1. Wepụ betulin na ethanol ngwọta.Mgbe kpochara reflux ihe dị ka awa 5, a na-ewepụ ihe ndị ahụ na-ekpo ọkụ ma tinyegharị ya na ethanol ugboro 2 ruo 3 na ethanol iji nweta ngwaahịa betulin.2. The crude ngwaahịa e recrystallized si methanol / chloroform (1: 1) (ọ bụla 80g crude ngwaahịa chọrọ 300mL methanol / chloroform ngwọta) A na-ekwe ka ngwakọta guzoro n'abali wee suction filtered iji nweta ọcha agịga-dị ka betulin.3. Ultrasonic ọgwụgwọ maka 20min mgbe refluxing a rụrụ, na mmịpụta mkpụrụ na ngwaahịa ịdị ọcha nke betulin nwere ike mma site na mbibi nke ogbugbo nzukọ.4. Ọnọdụ kachasị mma nke mmịpụta mmiri CO2 dị oke egwu bụ ndị a: ọnụọgụ mgbanwe bụ 115mL / (g birch ogbugbo ntụ ntụ);mmịpụta nrụgide bụ 20MPa;mmịpụta okpomọkụ bụ 55 ℃;mmiri mmiri CO2 eruba ọnụego bụ 10kg / h.