Bicalutamide CAS 90357-06-5 API Ụlọ ọrụ dị elu nke ọrịa kansa prostate dị elu

Bicalutamide (CAS: 90357-06-5) bụ onye na-abụghị steroidal androgen antagonist, nke na-asọmpi androgen receptor androgen, na-egbochi nnabata nke androgen cellular, ma na-egbochi njikọ nke androgens na akụkụ ebumnuche.Ọ na-ejikọta ya na onye na-anabata androgen nke na-emepụta mgbagwoju anya, nke na-abanye n'ime oghere ma jikọta ya na nucleoprotein, n'ihi ya na-egbochi uto cell tumor.Ọ nwere ike ịbụ ọgwụ nke mbụ maka ọgwụgwọ palliative nke ọrịa kansa prostate dị elu.A malitere Bicalutamide na United Kingdom, ahịa mbụ ya n'ụwa niile, maka ọgwụgwọ ọrịa kansa prostate dị elu yana mgbakwunye LHRH analog ma ọ bụ nkedo ịwa ahụ.Antiandrogen nke na-abụghị nke steroidal, nke dị n'akụkụ akụkụ, bicalutamide na-egbochi omume nke dihydrotestosterone na testosterone na saịtị ebumnuche site na njide asọmpi na cytosolic androgen receptor.A kọrọ na a kwadoro ya nke ọma n'enweghị mmetụta dị egwu nke obi na akwara ozi n'ihi uru nke enweghị ọrụ steroid ọ bụla.E gosipụtawo ịdị irè nke bicalutamide dị ka monotherapy na ụlọ ọgwụ.A kọkwara ọnụego nzaghachi na-ekwe nkwa na ọgwụgwọ colorectal, ara, pancreas na ọrịa cancer akpa ume na-abụghị obere cell.