Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Ụlọ ọrụ
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta Biotin (Vitamin H) (CAS: 58-85-5) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Aha Chemical | Biotin |
| Ụdị okwu | D-Biotin;D (+) - Biotin;Vitamin H;Bios II;Vitamin B7;Coenzyme R;Biotinum |
| Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
| Nọmba CAS | 58-85-5 |
| Usoro ihe omimi | C10H16N2O3S |
| Ibu molekụla | 244.31 g/mol |
| Ebe Na-agbaze | 231.0 ~ 233.0 ℃ (ọkụ) |
| Mmiri Solubility | Dị ntakịrị Soluble na Mmiri |
| Solubility na 0.1mol/L NaOH | Ihe fọrọ nke nta ka ọ bụrụ nghọta |
| Solubility | Na-agbaze ntakịrị na mmanya mmanya, Chloroform, Ether |
| COA & MSDS | Dị |
| Mmalite | Shanghai, China |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ | White Crystalline ntụ ntụ |
| njirimara | Dakọtara IR na ntụnye aka IR Spectrum | Na-akwado |
| Oge njide | Kwesịrị ịdị ka nke RS | Na-akwado |
| Ntụgharị a kapịrị ọnụ [a]20/D | +89.0° ruo +93.0° (C=2 na 0.1 M NaOH) | + 90.8 Celsius |
| Nyocha | 97.5 ~ 100.5% | 99.8% |
| Ọnwụ na ihicha | <0.50% | 0.05% |
| Ihe ndị emetụtara | ||
| Ọdịghị ọcha nke Onwe Onye | <1.00% | Na-akwado |
| Mgbakọta adịghị ọcha | <2.00% | Na-akwado |
| Ihe mgbaze fọdụrụnụ | ||
| Benzene | <2pm | <0.2pm |
| Toluene | <100ppm | <10ppm |
| DMSO | <5000ppm | <500ppm |
| Nnwale Microbial | ||
| Ngụkọta ọnụ ọgụgụ ikuku ikuku nwere ike ime | ≤1000cfu/g | Na-akwado |
| Ngụkọta yist na ebu | ≤100cfu/g | Na-akwado |
| Escherichia Coli | ND/1g | / |
| Staphylococcus Aureus | ND/1g | / |
| Pseudomonas Aeruginosa | ND/1g | / |
| Enterobacteria | ND/1g | / |
| Ụdị Salmonella | ND/10g | / |
| Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe nke ọma na-esi na ihe ndị na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Nkọwa nkọwa Biotin nwere NLT 97.5% na NMT 100.5% nke Biotin (C10H16N2O3S).
Nchọpụta
• A. INFRARED ABSORPATION <197K>
B. Ọ na-emezu ihe ndị a chọrọ na Nnwale Specific for Optical Rotation, Specific Rotation <781S>.
C. Oge njide nke isi ọnụ ọgụgụ kachasị elu nke ngwọta Sample dabara na nke ọkọlọtọ Standard, dị ka enwetara na Assay.
ASSAY
• Usoro
Ngwọta nchekwa: igbari 1 g nke sodium perchlorate monohydrate na 500 ml mmiri, gbakwunye 1 ml nke phosphoric acid, ma jiri mmiri gbanye 1000 ml.
Usoro mkpanaaka: Acetonitrile na ihe ngwọta (8.5: 91.5)
Ihe mgbaze: acetonitrile na mmiri (1: 4)
Ngwọta ọkọlọtọ: 0.1 mg/mL nke USP Biotin RS na diluent.Sonicate ma ọ bụrụ na ọ dị mkpa ka igbari
Ngwọta nlele: 0.1 mg/mL nke Biotin na diluent.Sonicate ma ọ bụrụ na ọ dị mkpa ka igbari.
Sistemụ chromatographic
(Lee Chromatography <621>, Kwesịrị ekwesị Sistemu.)
Ụdị: LC
Ihe nchọpụta: UV 200 nm
Ogidi: 4.6-mm × 15-cm;3-µm nkwakọ ngwaahịa L7
Ọnụego mmiri: 1.2 ml / min
Nha igba ogwu: 50µL
Sistemu kwesịrị ekwesị
Ihe atụ: Ngwọta ọkọlọtọ
Kwesịrị ekwesị chọrọ
Ihe kpatara ọdụdụ: NMT 1.5
Ọkọlọtọ emetụtara: NMT 2.0% maka injections oyiri
Nyocha
Ihe atụ: Ngwọta ọkọlọtọ na ngwọta nlele
Gbakọọ pasent Biotin (C10H16N2O3S) na akụkụ Biotin were:
Nsonaazụ = (rU/rS) × (CS/CU) × 100
rU = nzaghachi kacha elu sitere na ngwọta Sample
rS = nzaghachi kacha elu sitere na ngwọta Standard
CS = ntinye uche nke USP Biotin RS na ngwọta ọkọlọtọ (mg/mL)
CU = ntinye uche nke Biotin na ngwọta nlele (mg/mL)
Usoro nnabata: 97.5% -100.5%
IHE adịghị ọcha
• Ngwakọta ejikọtara
Ngwọta nchekwa, usoro mkpanaka, Diluent, Ọkọlọtọ ngwọta, Ngwọta nlele, Sistemụ Chromatographic na ndabara sistemu: Gaba n'ihu dị ka enyere ya na Assay.
Nyocha
Ihe atụ: Ngwọta nlele
Tule nzaghachi kacha elu nke ngwọta Sample.
Gbakọọ pasent nke adịghị ọcha ọ bụla na akụkụ Biotin were:
Nsonaazụ = (rU/rT) × 100
rU = nzaghachi kacha elu nke adịghị ọcha ọ bụla sitere na ngwọta Sample
rT = nchikota nzaghachi kacha elu nke ọnụ ọgụgụ kacha elu sitere na ngwọta Sample
Usoro nnabata
adịghị ọcha nke onwe: NMT 1.0%
Mkpokọta adịghị ọcha: NMT 2.0%
Nnwale akọwapụtara
• Ntụgharị anya, ntụgharị a kapịrị ọnụ <781S>
Ngwọta nlele: 20 mg/mL na 0.1 N sodium hydroxide
Usoro nnabata: +89° ruo +93°
NKWUO GBASARA YA
• Nkwakọba na Nchekwa: Chekwaa n'ime akpa siri ike.
• Ụkpụrụ ntụaka USP <11>
USP Biotin RS
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
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Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Ihe akara egwu Xn - na-emerụ ahụ
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WGK Germany 1
RTECS XJ9088200
FLUKA BRAND F CODES 8
TSCA Ee
Koodu mpaghara:: 2936290000
Nsi LD50 ọnụ na oke bekee:> 2000 mg/kg
Biotin (Vitamin H; Vitamin B7) (CAS: 58-85-5)
Biotin bụ vitamin na-agbaze mmiri n'ụdị asatọ, biotin.Ọ bụ coenzyme - ma ọ bụ onye inyeaka enzyme - eji na ọtụtụ mmeghachi omume metabolic na ahụ.Dchemicalbook-biotin na-etinye aka na lipid na protein metabolism, na-enyere aka ịtụgharị nri ka ọ bụrụ glucose, nke ahụ nwere ike iji dị ka ike.Ọ dịkwa mkpa maka ịkwado akpụkpọ anụ, ntutu na akpụkpọ anụ mucous.
Dị ka ihe mgbakwunye nri, a na-eji Biotin eme ihe maka anụ ọkụkọ na ịgha mkpụrụ.Ọtụtụ mgbe, ụmụ irighiri ihe ejikọtara ọnụ bụ 1%-2%.
Biotin bụ ihe mgbakwunye nri.Dịka iwu China GB2760-90 si kwuo, enwere ike iji ya dị ka ụlọ ọrụ nri dịka enyemaka nhazi.Ọ nwere ọrụ physiological iji gbochie ọrịa anụ ahụ ma kwalite metabolism lipid na ihe ndị ọzọ.
Biotin bụ carboxylase coenzyme, na-etinye aka na ọtụtụ mmeghachi omume carboxylation, yana coenzyme dị mkpa na metabolism nke shuga, protein na abụba.
A na-eji Biotin eme ihe ike nri.A na-eji Biotin maka nri ụmụ ọhụrụ nwere oke 0.1 ~ 0.4mg / kg, na mmiri ọṅụṅụ 0.02 ~ 0.08mg / kg.
Enwere ike iji Biotin maka ịkpọ protein, antigens, antibodies, acid nucleic (DNA, RNA) na ndị ọzọ.
Biotin nwere ike ime ka ntutu na-agbanwe, gbochie ntutu isi n'oge ma melite nguzogide okike nke akpụkpọ ahụ.Ọ nwekwara ụfọdụ irè mgbochi wrinkle.Ọ nwere ike ịkwalite nhazi nhazi nke akpụkpọ ahụ n'ozuzu ya, na-eme ka mgbanwe nke mbọ dịkwuo mma, melite nhazi nke mbọ na-agbaji ma mee ka mbọ dịkwuo mma ma dị mma site n'ịkwalite njikọ nke lipids.
Enweghị biotin nwere ike ịkpata dermatitis, atrophic glossitis, hyperesthesia, myalgia, malaise, anorexia, na obere anaemia, na mgbaàmà na-apụ n'anya site na mgbakwunye biotin.Mmetụta ọ na-enwekarị bụ ntiwapụ nke otutu cystic.Ma maka ọtụtụ ndị mmadụ, ọbụna ịṅụbiga mmanya ókè nke vitamin a adịghị akpata mmetụta ọjọọ.Otú ọ dị, ndị inyom dị ime ekwesịghị ịṅụ biotin n'ihi ihe ize ndụ nke ime ọpụpụ.
Nsi nke Biotin yiri ka ọ dị ala, ọgwụgwọ nke seborrheic dermatitis na nnukwu doses nke Biotin ekpughere adịghị mma nke protein metabolism ma ọ bụ njehie mkpụrụ ndụ ihe nketa na ọrịa ndị ọzọ metabolic.Nnwale anụmanụ gosikwara ntakịrị nsi nke Biotin.
