Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8 Dị Ọcha ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate
Nnweta Sitagliptin Phosphate Monohydrate Njikọta:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
| Aha Chemical | Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid |
| Ụdị okwu | (R)-Sitagliptin N-Boc-Acid adịghị ọcha |
| Nọmba CAS | 486460-00-8 |
| Nọmba CAT | RF-PI1192 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C15H18F3NO4 |
| Ibu molekụla | 333.31 |
| Ebe Na-agbaze | 136.0 ~ 138.0 ℃ |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
| Nchọpụta nke HPLC | Oge njide nke Sample bụ Nkwekọrịta na ọkọlọtọ ntụaka |
| Ọnwụ na ihicha | ≤0.50% |
| Sulfated Ash | ≤0.50% |
| Ọla dị arọ | <20ppm |
| Isomer | ≤0.50% |
| Ihe ndị emetụtara | |
| adịghị ọcha A | ≤0.50% |
| Ọdịghị ọcha ọ bụla ọzọ | ≤0.50% |
| Mgbakọta adịghị ọcha | ≤0.50% |
| Ịdị ọcha | ≥99.5% (HPLC) |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid (CAS: 486460-00-8) bụ etiti dị mkpa maka nkwadebe nke sitagliptin.Sitagliptinphosphate bụ dipeptidase -IV (DPP-4) inhibitor nke FDA kwadoro na 2006. A na-eji ya maka ọgwụgwọ ụdị ọrịa shuga mellitus nke II.Ọ nwere mmetụta hypoglycemic doro anya mgbe ejiri ya naanị ya ma ọ bụ yana metformin na pioglitazone, ọ dịkwa mma ị were ya nke ọma, yana mmeghachi omume ọjọọ ole na ole.N'August 2009, European Union kwadoro ọgwụ ahụ dị ka ọgwụ mbụ maka ọgwụgwọ ụdị ọrịa shuga 2.Ka 2011 gachara, otu mba ọzọ akwadola ngwakọta nke sitagliptin phosphate na alfa glycosidase inhibitors ma ọ bụ insulin.Sitagliptin phosphate bụ nke mbụ FDA kwadoro dipeptidyl peptidase-IV inhibitor nke a ga-eji na-agwọ ụdị ọrịa shuga 2 ruo ogologo oge, n'okpuru aha ahia Januvia.
