Captopril CAS 62571-86-2 API Ụlọ ọrụ USP Mgbochi ọbara mgbali elu dị elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha ọgwụ: Captopril
Nọmba: 62571-86-2
Enzyme na-agbanwe Angiotensin na-arụ ọrụ (ACE) mgbochi ọbara mgbali elu
API Ogo dị elu, mmepụta azụmahịa
| Aha Chemical | Captopril |
| Ụdị okwu | (S) (-) -1- (3-Mercapto-2-methyl-1-oxopropyl) -L-proline;(S) (-) -1- (3-Mercapto-2-methylpropionyl) -L-proline |
| Nọmba CAS | 62571-86-2 |
| Nọmba CAT | RF-API89 |
| Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
| Usoro ihe omimi | C9H15NO3S |
| Ibu molekụla | 217.29 |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
| Nyocha | 98.0% ~ 102.0% (na akọrọ ndabere) |
| Ebe Na-agbaze | 104.0 ~ 110.0 ℃ |
| Ntụgharị ngwa anya akọwapụtara | -125.0° ruo -134.0° |
| Acidity | 7.0-8.0 |
| Ọnwụ na ihicha | ≤1.0% |
| Ihe fọdụrụ na mgbanye | ≤0.10% |
| Ọla dị arọ | ≤20ppm |
| Ihe ndị emetụtara | |
| Captopril disulfide | ≤1.0% |
| Otu adịghị ọcha amaghi ama | ≤0.20% |
| Mgbakọta adịghị ọcha | ≤0.50% |
| Ihe adịghị ọcha nke Organic | Na-emezu ihe achọrọ |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ejiri ya dị ka ọgwụ mgbochi ọbara mgbali elu |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Captopril bụ nke a kacha mụọ gbasara ihe mgbochi angiotensin-converting enzyme (ACE) nke akwadoro dị ka ọgwụ mgbochi hypertensive.Ọ na-egbochi angiotensin-na-atụgharị enzyme, nke na-egbochi nhazi nke angiotensin II ma na-ebelata mmetụta vasoconstrict ya na arịa akwara na venous.N'ozuzu vaskụla mpụta erughị ala na-ebelata, nke na-ebute mbelata nke akwara akwara.A na-egosi Captopril, yana ndị na-egbochi ACE ndị ọzọ na ọgwụgwọ ọbara mgbali elu, nkụchi obi nke nkụchi obi, arụ ọrụ ventricular aka ekpe mgbe myocardial infarction gasịrị, na ọrịa shuga nephropathy.N'ime ọgwụgwọ ọbara mgbali elu dị mkpa, a na-ewere captopril dị ka usoro ọgwụgwọ mbụ, ma ọ bụ naanị ya ma ọ bụ yana yana thiazide diuretic.A na-ebute mbelata nke ọbara mgbali elu n'ihi mbelata mkpokọta nguzogide mpụta ma ọ bụ ibugharị ya.Uru nke ijikọta ọgwụgwọ captopril na thiazide diuretic a na-ahụkarị bụ na a na-ebelata hypokalemia nke thiazide na-akpata n'ihu mgbochi ACE, ebe ọ bụ na mbelata nke mwepu nke angiotensin II na-ebute aldosterone.
