4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile CAS 143782-23-4 Enzalutamide Intermediate Dị ọcha>98.0% (GC)
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta 4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile (CAS: 143782-23-4) nke nwere àgwà dị elu, etiti nke Enzalutamide (CAS: 915087-33-1).Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Enzalutamide Intermediates,Please contact: alvin@ruifuchem.com
Aha Chemical | 4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile |
Ụdị okwu | 4-Cyano-3- (Trifluoromethyl) phenyl Isothiocyanate;Isothiocyanic Acid 4-Cyano-3- (Trifluoromethyl) phenyl Ester;4-Isothiocyanato-2-Trifluoromethylbenzonitrile;3-Fluoro-4-Methylphenylisothiocyanate |
Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
Nọmba CAS | 143782-23-4 |
Usoro ihe omimi | C9H3F3N2S |
Ibu molekụla | 228.19 g/mol |
Ebe Na-agbaze | 39.0 ruo 43.0 ℃ |
Ebe esi nri | 331 ℃ |
Ebe mgbari | 154 ℃ |
Njupụta | 1.31 |
Mmetụta | Mmiri Na-enwe Mmetụta, Okpomọkụ Na-enwe Mmetụta |
COA & MSDS | Dị |
Ihe atụ | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta | Nsonaazụ |
Ọdịdị | Gbanyụọ-Ọcha ntụ ntụ | Gbanyụọ-Ọcha ntụ ntụ |
Ebe Na-agbaze | 39.0 ruo 43.0 ℃ | 41.2 ℃ |
Ọnwụ na ihicha | <0.50% | 0.19% |
Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) | 98.8% |
Spectrum infrared | Nkwekọ na Structure | Na-akwado |
1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
Ngwa | Ọkara nke Enzalutamide (CAS: 915087-33-1) |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe nke ọma na-esi na ihe ndị na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
H302 + H312 + H332: Ọ na-emerụ ahụ ma ọ bụrụ na iloro ya, na kọntaktị na akpụkpọ ahụ ma ọ bụ ọ bụrụ na a kuruo ya.
H315: na-ebute mgbakasị anụ ahụ.
H319: Na-ebute oke iwe anya.
H335: nwere ike ịkpata mgbakasị iku ume.
P501: Tụfuo ọdịnaya/akpa n'ụlọ ọrụ mkpofu akwadoro.
P261: Zere uzuzu iku ume / uzuzu / gas / alụlụ / vapors / ịgba.
P270: erila, aṅụ ma ọ bụ anwụrụ ọkụ mgbe ị na-eji ngwaahịa a.
P271: Jiri naanị n'èzí ma ọ bụ na mpaghara ikuku nke ọma.
P264: saa anụ ahụ nke ọma mgbe ejirichara ya.
P280: Yiri gloves nchebe / uwe nchebe / nchebe anya / nchebe ihu.
P337 + P313: Ọ bụrụ na mgbakasị ahụ anya na-aga n'ihu: Nweta ndụmọdụ/nleba anya ahụike.
P305 + P351 + P338: Ọ BỤRỤ NA ANYỊ: Jiri nlezianya sachaa mmiri ruo ọtụtụ nkeji.Wepu lensị kọntaktị, ọ bụrụ na ọ dị ma dị mfe ime.Gaa n'ihu na-asachapụ.
P332 + P313: Ọ bụrụ na mgbakasị ahụ akpụkpọ emee: Nweta ndụmọdụ ahụike / nlebara anya.
P362: Yipụ uwe emerụrụ emerụ ma saa tupu ejigharịa ya.
P301 + P312 + P330: Ọ BỤRỤ NA EKWU: Kpọọ CENTER POISON / Dọkịta ma ọ bụrụ na ahụ adịghị gị mma.Sachaa ọnụ.
P302 + P352 + P312: Ọ BỤRỤ NA AKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWASỊ: Kpọọ ụlọ ọgwụ POISON CENTER ma ọ bụrụ na ahụ adịghị gị.
P304 + P340 + P312: Ọ BỤRỤ na-ekunye ya: Wepụ mmadụ gaa n'ikuku dị ọhụrụ ma nwee ahụ iru ala maka iku ume.Kpọọ CENTER POISON / Dọkịta ma ọ bụrụ na ahụ adịghị gị mma.
P403 + P233: Chekwaa n'ebe ikuku na-ekpo ọkụ.Debe akpa ahụ nke ọma.
P405: Akpọchiri ụlọ ahịa.
A na-eji 4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile (CAS: 143782-23-4) dị ka etiti nke Enzalutamide (CAS: 915087-33-1).Enzalutamide (XTANDI) bụ onye na-anabata androgen receptor antagonist, nke akwadoro site na nyocha ụlọ ọgwụ ugbu a yana US FDA (Nchịkwa nri na ọgwụ ọjọọ), maka mmepe nke post-chemotherapy metastatic castration nnabata nke ọrịa cancer prostate (ya bụ, ndị ọrịa nwere ọrịa kansa prostate). mgbe chemotherapy gasịrị, ọrịa kansa ma ọ bụ mkpụrụ ndụ kansa ka na-eto eto na ndị ọrịa dị otú ahụ), nwere ike ịgbatị ndụ ndị ọrịa.N'August 2012, US FDA kwadoro enzalutamide maka ọgwụgwọ nke ọrịa cancer prostate na-eguzogide metastatic castration (mCRPC) n'ime ndị ọrịa ejirila ọgwụgwọ na mbụ.Docetaxel.