2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel Intermediate Ịdị ọcha>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) nwere àgwà dị elu, etiti nke Perampanel (CAS: 380917-97-5).Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta ndị etiti Perampanel, Please contact: alvin@ruifuchem.com
| Aha Chemical | 2-Cyanophenylboronic Acid 1,3-Propanediol Ester |
| Ụdị okwu | 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2- (1,3,2-Dioxaborinan-2-yl) benzonitrile |
| Nọmba CAS | 172732-52-4 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C10H10BNO2 |
| Ibu molekụla | 187.01 |
| Ebe Na-agbaze | 46.0 ~ 51.0 ℃ (ọkụ) |
| Njupụta | 1.13±0.10 g/cm3 |
| Solubility | Soluble na methanol |
| Nkwụsi ike | Hygroscopic |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha na-acha odo odo ka ọ bụrụ kristal |
| Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
| Ọnwụ na ihicha | <0.50% |
| Ihe fọdụrụ na mgbanye | <0.20% |
| Otu adịghị ọcha | <0.50% |
| Mgbakọta adịghị ọcha | <1.00% |
| Ọla dị arọ (dị ka Pb) | <20ppm |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Perampanel (CAS: 380917-97-5) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Ihe akara egwu Xi - iwe
Koodu ihe egwu
R20/21/22 - na-emerụ ahụ site na iku ume, na kọntaktị na akpụkpọ ahụ ma ọ bụrụ na loro ya.
R36 / 37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
Nkọwapụta nchekwa
S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36/37/39 - Yiri uwe nchebe kwesịrị ekwesị, uwe aka na nchebe anya / ihu.
Nọmba UN 3439
WGK Germany 3
TSCA Mba
Ihe ndetu Hazard na-ewe iwe
A na-eji 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) na njikọ nke Perampanel (CAS: 380917-97-5), onye na-anabata AMPA.Perampanel (nke enyere ikike na 2012) bụ ọgbọ nke atọ AED mara aha njirimara nke Fycompa® (Eisai, Hatfield) na UK yana Banzel® (Eisai, Hatfield) na USA.N'October 2012, US FDA kwadoro perampanel maka ọgwụgwọ nke obere mmalite mmalite na ndị ọrịa akwụkwụ bụ ndị dịkarịa ala afọ 12.Perampanel bụ onye na-anabata AMPA mbụ na-anata nkwado FDA dị ka AED.A na-ahụ ndị na-anabata AMPA glutamate nke ọma na neurons postsynaptik na ụbụrụ.Dị ka onye na-ahọrọ, onye mmegide na-enweghị asọmpi nke AMPA, parampanel na-egbochi imeghe ọwa ion ma belata mgbasa nke ike omume.Ndị European EMA na US FDA kwadoro Perampanel na Julaị na Ọktoba 2012 n'otu n'otu, a na-eji ya maka ọgwụgwọ adjuvant nke ndị ọrịa nwere akụkụ ọdịdọ karịa afọ 12 na-enwe ma ọ bụ na-enweghị usoro ọdịdọ nke abụọ.Na June 22, 2015, Eisai mara ọkwa na US FDA akwadowo mgbasawanye nke egosi Pirenparanide hydrate (Fycompa) dị ka ihe adjuvant ọgwụgwọ maka isi keukwu tonic-clonic ọdịdọ na ndị ọrịa nwere Akwụkwụ na-adọ 12 na n'elu.
