Posaconazole Intermediate CAS 175712-02-4 Ịdị ọcha> Ụlọ ọrụ 99.0% (GC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta Posaconazole Intermediate (CAS: 175712-02-4) nwere àgwà dị elu.Ruifu Chemical na-enye usoro nke etiti ọgwụ.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Posaconazole Intermediate,Please contact: alvin@ruifuchem.com
Aha Chemical | Posaconazole Intermediate |
Ụdị okwu | Posaconazole adịghị ọcha 21;(5R-Cis) - P-Chlorobenzenesulfonic Acid 5;[(3S, 5R) -5- (2,4-Difluorophenyl) -5- (1,2,4-triazol-1-ylmethyl) tetrahydrofuran-3-yl] methyl 4-Chlorobenzenesulfonate;(3S-cis) -4-Chlorobenzenesulfonic Acid [5- (2,4-Difluorophenyl) tetrahydro-5- (1H-1,2,4-triazol-1-ylmethyl) -3-Furanyl] methyl Ester |
Ọnọdụ Ahịa | Dị na ngwaahịa |
Nọmba CAS | 175712-02-4 |
Usoro ihe omimi | C20H18ClF2N3O4S |
Ibu molekụla | 469.89 g/mol |
Njupụta | 1.49±0.10 g/cm3 |
Okpomọkụ nchekwa. | Ebe dị jụụ na nkụ (2 ~ 8 ℃) |
COA & MSDS | Dị |
Otu | Ndị na-ahụ maka ọgwụ |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | Ọcha siri ike | Ọcha siri ike |
Mmiri nke Karl Fischer | <0.50% | 0.20% |
Ụzọ ịdị ọcha / nyocha | > 99.0% (GC) | 99.3% |
1 H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
LCMS | Nkwekọ na Structure | Na-akwado |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwapụta |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa agbachiri agbachi n'ụlọ nkwakọba ihe dị jụụ na nke kpọrọ nkụ dịpụrụ adịpụ site na ihe na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Nyefee n'ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Posaconazole Intermediate (CAS: 175712-02-4) bụ etiti nke Posaconazole (CAS: 171228-49-2).Posaconazole, nke ewepụtara na UK, bụ onye kachasị ọhụrụ na klas azole nke ọgwụ nje iji rute n'ahịa.A na-egosi ya maka ọgwụgwọ na mgbochi nke ọrịa fungal dị iche iche, gụnyere aspergillosis, fusariosis, chromoblastomycosis, mycetoma, na coccidiomycosis na ndị ọrịa na-anabataghị, ma ọ bụ na-anabataghị ọgwụgwọ ọkọlọtọ na amphotericin B na / ma ọ bụ itraconazole.Na US, a kwadoro ya maka prophylaxis nke ọrịa Aspergillus na Candida na-efe efe na ndị ọrịa dị afọ 13 bụ ndị nọ n'ihe ize ndụ nke ịmalite ọrịa ndị a n'ihi enweghị mgbochi mgbochi.Ọzọkwa, a kwadoro ya maka ọgwụgwọ nke oropharyngeal candidiasis.Posaconazole nwere ọrụ dị iche iche gbasaara karịa ndị ọzọ so na azole antifungals.Na mgbakwunye na ọrụ siri ike megide ọrịa refractory nke aspergillosis na Candida na-eguzogide fluconazole, ọ na-egosipụta ọrụ megide Zygomycetes.
Biochem/Physiol Actions Posaconazole bụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọ dị ike megide nje yist nke Candida sp.Ọ na-egbochi uto nke fungi site na igbochi enzyme lanosterol 14a-demethylase (CYP51).N'adịghị ka azoles antifungal ndị ọzọ, a kọwo na posaconazole ọ bụghị ịkpata usoro mgbapụta efflux.Posaconazole na-egosipụta mmetụta antichagasic megide ụdị dị iche iche nke Trypanosoma cruzi na-akpata ọrịa Chagas.
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