Posaconazole Intermediate CAS 175712-02-4 Ịdị ọcha> Ụlọ ọrụ 99.0% (GC)

Nkọwa dị mkpirikpi:

Aha Chemical: Posaconazole Intermediate

Nọmba: 175712-02-4

Dị ọcha:> 99.0% (GC)

Ọdịdị: White Solid

Ọkara nke Posaconazole (CAS: 171228-49-2)

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta Posaconazole Intermediate (CAS: 175712-02-4) nwere àgwà dị elu.Ruifu Chemical na-enye usoro nke etiti ọgwụ.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Posaconazole Intermediate,Please contact: alvin@ruifuchem.com

Njirimara kemịkalụ:

Aha Chemical Posaconazole Intermediate
Ụdị okwu Posaconazole adịghị ọcha 21;(5R-Cis) - P-Chlorobenzenesulfonic Acid 5;[(3S, 5R) -5- (2,4-Difluorophenyl) -5- (1,2,4-triazol-1-ylmethyl) tetrahydrofuran-3-yl] methyl 4-Chlorobenzenesulfonate;(3S-cis) -4-Chlorobenzenesulfonic Acid [5- (2,4-Difluorophenyl) tetrahydro-5- (1H-1,2,4-triazol-1-ylmethyl) -3-Furanyl] methyl Ester
Ọnọdụ Ahịa Dị na ngwaahịa
Nọmba CAS 175712-02-4
Usoro ihe omimi C20H18ClF2N3O4S
Ibu molekụla 469.89 g/mol
Njupụta 1.49±0.10 g/cm3
Okpomọkụ nchekwa. Ebe dị jụụ na nkụ (2 ~ 8 ℃)
COA & MSDS Dị
Otu Ndị na-ahụ maka ọgwụ
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Ụkpụrụ nyocha Nsonaazụ
Ọdịdị Ọcha siri ike Ọcha siri ike
Mmiri nke Karl Fischer <0.50% 0.20%
Ụzọ ịdị ọcha / nyocha > 99.0% (GC) 99.3%
1 H NMR Spectrum Nkwekọ na Structure Na-akwado
LCMS Nkwekọ na Structure Na-akwado
Mmechi A nwalela ngwaahịa a wee kwado nkọwapụta

Ngwugwu/Nkwakọba/Mbupu:

ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa agbachiri agbachi n'ụlọ nkwakọba ihe dị jụụ na nke kpọrọ nkụ dịpụrụ adịpụ site na ihe na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Nyefee n'ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.

Uru:

Ike zuru oke: akụrụngwa na ndị ọrụ nka zuru oke

Ọrụ Ọkachamara: Otu nkwụsị ịzụrụ ọrụ

Ihe ngwugwu OEM: ngwugwu omenala na akara dị

Nnyefe ngwa ngwa: Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ

Nkwanye kwụsiri ike: Jikwaa ngwaahịa ezi uche dị na ya

Nkwado nka na ụzụ: Ngwọta teknụzụ dị

Ọrụ Synthesis Custom: sitere na gram ruo kilos

Ogo dị elu: guzobe usoro mmesi obi ike zuru oke

Ajụjụ:

Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.

Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.

Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.

OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.

Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.

Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.

MOQ?Enweghị MOQ.A na-anabata obere usoro.

Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.

Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.

Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.

Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.

Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.

Ngwa:

Posaconazole Intermediate (CAS: 175712-02-4) bụ etiti nke Posaconazole (CAS: 171228-49-2).Posaconazole, nke ewepụtara na UK, bụ onye kachasị ọhụrụ na klas azole nke ọgwụ nje iji rute n'ahịa.A na-egosi ya maka ọgwụgwọ na mgbochi nke ọrịa fungal dị iche iche, gụnyere aspergillosis, fusariosis, chromoblastomycosis, mycetoma, na coccidiomycosis na ndị ọrịa na-anabataghị, ma ọ bụ na-anabataghị ọgwụgwọ ọkọlọtọ na amphotericin B na / ma ọ bụ itraconazole.Na US, a kwadoro ya maka prophylaxis nke ọrịa Aspergillus na Candida na-efe efe na ndị ọrịa dị afọ 13 bụ ndị nọ n'ihe ize ndụ nke ịmalite ọrịa ndị a n'ihi enweghị mgbochi mgbochi.Ọzọkwa, a kwadoro ya maka ọgwụgwọ nke oropharyngeal candidiasis.Posaconazole nwere ọrụ dị iche iche gbasaara karịa ndị ọzọ so na azole antifungals.Na mgbakwunye na ọrụ siri ike megide ọrịa refractory nke aspergillosis na Candida na-eguzogide fluconazole, ọ na-egosipụta ọrụ megide Zygomycetes.

Biochem/Physiol Actions Posaconazole bụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọ dị ike megide nje yist nke Candida sp.Ọ na-egbochi uto nke fungi site na igbochi enzyme lanosterol 14a-demethylase (CYP51).N'adịghị ka azoles antifungal ndị ọzọ, a kọwo na posaconazole ọ bụghị ịkpata usoro mgbapụta efflux.Posaconazole na-egosipụta mmetụta antichagasic megide ụdị dị iche iche nke Trypanosoma cruzi na-akpata ọrịa Chagas.

Dee ozi gị ebe a ziga anyị ya