Gefitinib Intermediate CAS 199327-61-2 Ịdị Ọcha>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na-emepụta 7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4 (3H) - Otu (CAS: 199327-61-2) na elu mma, etiti. nke Gefitinib (CAS: 184475-35-2).Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Gefitinib Intermediates,Please contact: alvin@ruifuchem.com
| Aha Chemical | 7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4(3H) - Otu |
| Ụdị okwu | 7-Methoxy-6- (3-Morpholinopropoxy) quinazolin-4 (3H) - Otu;7-Methoxy-6-[3- (4-Morpholinyl) propoxy] -4 (3H) -Quinazolinone;7-Methoxy-6- (3-Morpholinopropoxy) quinazolin-4-Otu. |
| adịghị ọcha | Gefitinib adịghị ọcha 5;Gefitinib EP adịghị ọcha A |
| Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
| Nọmba CAS | 199327-61-2 |
| Usoro ihe omimi | C16H21N3O4 |
| Ibu molekụla | 319.36 g/mol |
| Ebe Na-agbaze | 242.0 ~ 247.0 ℃ |
| Njupụta | 1.32±0.10 g/cm3 |
| COA & MSDS | Dị |
| Mmalite | Shanghai, China |
| Ụdị | Ruifu Chemical |
| Ihe | Ụkpụrụ nyocha | Nsonaazụ |
| Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ | Na-akwado |
| Ebe Na-agbaze | 242.0 ~ 247.0 ℃ | 243.6 ~ 244.5 ℃ |
| Ọnwụ na ihicha | <0.50% | 0.15% |
| Ihe fọdụrụ na mgbanye | <0.20% | 0.11% |
| Otu adịghị ọcha | <0.50% | <0.30% |
| Mgbakọta adịghị ọcha | <1.00% | 0.30% |
| Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) | 99.7% |
| 1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
| Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
| Ngwa | Ọkara nke Gefitinib (CAS: 184475-35-2) | |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe nke ọma na-esi na ihe ndị na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
7-Methoxy-6- (3-Morpholin-4-ylpropoxy) quinazolin-4 (3H) - Otu (CAS: 199327-61-2) bụ etiti / adịghị ọcha nke Gefitinib (CAS: 184475-35-2).Gefitinib bụ ọgwụ ọgwụgwọ ezubere iche maka mgbochi tumor nke AstraZeneca, UK mepụtara.Gefitinib bụ ọgwụ izizi ezubere iche nke mkpụrụ ndụ maka ọgwụgwọ ọrịa kansa akpa ume na-abụghị obere cell.Ọ na-arụ ọrụ site n'ịhọrọ igbochi ụzọ ntụgharị mgbaàmà nke epidermal growth factor receptor tyrosine kinase (EGFR-TK).N'August 2002, a na-ere Gefitinib na Japan dị ka ọgwụgwọ mbụ maka ọrịa cancer akpa ume na-abụghị obere cell n'okpuru aha ahia Iressa.Na May 2003, US Food and Drug Administration kwadoro Gefitinib dị ka usoro ọgwụgwọ nke atọ maka ndị ọrịa nwere ọrịa cancer akpa ume na-abụghị obere cell bụ ndị na-adịghị arụ ọrụ na ọgwụ anticancer nke platinum dabeere na docetaxel chemotherapy.Ka ọ dị ugbu a, Australia, Japan, Argentina, Singapore na South Korea akwadola Gefitinib maka ọgwụgwọ ọrịa kansa akpa ume na-abụghị obere cell.Na February 28, 2005, Ụlọ Ọrụ Nri na Ọgwụ nke China kwadoro Gefitinib maka ọgwụgwọ ọrịa cancer akpa ume na mpaghara ma ọ bụ metastatic na-abụghị obere cell (NSCLC) nke natara na mbụ chemotherapy.A kwadobeghị ya ugbu a maka ojiji dị ka usoro ọgwụgwọ mbụ maka NSCLC dị elu.Na Julaị 1, 2009, Agencylọ Ọrụ Ọgwụ na Europe kwadoro Gefitinib maka ọgwụgwọ nke mbụ, ahịrị nke abụọ na ahịrị nke atọ nke ọrịa cancer akpa ume na mpaghara ma ọ bụ metastatic na-abụghị obere cell na mmụgharị mkpụrụ ndụ EGFR na ndị okenye.
