3-Chloro-4- (3-Fluorobenzyloxy) aniline CAS 202197-26-0 Lapatinib Intermediate Dị ọcha> 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta 3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Lapatinib Intermediates,Please contact: alvin@ruifuchem.com
Aha Chemical | 3-Chloro-4- (3-Fluorobenzyloxy) aniline |
Ụdị okwu | 3-Chloro-4-[(3-Fluorophenyl) methoxy] aniline;4- (3-Fluorobenzyloxy) -3-Chlorobenzenamine;Lapatinib Intermediate B |
Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
Nọmba CAS | 202197-26-0 |
Usoro ihe omimi | C13H11ClFNO |
Ibu molekụla | 251.69 g/mol |
Ebe Na-agbaze | 78.0 ruo 82.0 ℃ |
Njupụta | 1.306±0.06 g/cm3 |
COA & MSDS | Dị |
Ihe atụ | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | Brown ka oji ntụ ntụ | Na-akwado |
Ebe Na-agbaze | 78.0 ruo 82.0 ℃ | 80.7 ℃ |
Ọnwụ na ihicha | <1.00% | Na-akwado |
Ihe fọdụrụ na mgbanye | <0.50% | Na-akwado |
Ihe ndị emetụtara nke HPLC | <2.00% | 0.64% |
Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) | 99.36% |
1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
Ngwa | Ọkara nke Lapatinib / Lapatinib Ditosylate Monohydrate |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma debe ya n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na nke ikuku na-ekpo ọkụ n'ebe ihe na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Nọmba UN 3077
Koodu HS 2921420090
Klas 9 egwu
Otu ngwugwu III
3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) bụ etiti na njikọ nke Lapatinib / Lapatinib Ditosylate Monohydrate.
Lapatinib bụ ọgwụ ezubere iche maka ọrịa ara ara nke British GlaxoSmithKline Co. Human ErbB anabata so n'ụdị ezinụlọ nnabata tyrosine kinase (TK), gụnyere ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), na ErbB4 (HER4) .Ndị na-anabata ErbB-1 (EGFR) na ErbB-2 (HER-2) na-enwekarị oke ma ọ bụ gbanwee na ndị ọrịa cancer.Onye na-anabata ihe na-eto eto epidermal 2 (ErbB-2, HER-2) ka amara na ọ bụ oncogene mmadụ nwere njikọ chiri anya na ọrịa kansa ara.Ngosipụta ya dị elu na ọrịa kansa ara na-ebukarị amụma metastasis nke lymph node na ọdịiche dị njọ nke etuto ahụ, na-enwe amụma na-adịghị mma.HER-2 bụ otu n'ime ụmụ irighiri ihe echere maka ọgwụgwọ ọrịa kansa ara.Lapatinib nwere ike ime ihe n'otu oge na ma Her-1 Her-2.Mmetụta ndụ nke usoro a na-egbochi mmụba na uto nke mkpụrụ ndụ tumo dị ukwuu karịa ime naanị otu ebumnuche.A na-eji ngwakọta Lapatinib na Capecitabine na-agwọ ndị ọrịa nwere ọrịa ara ara dị elu ma ọ bụ metastatic na-egosipụta oke nke epidermal receptor2, nke ejirila anthracyclines, paclitaxel na trastuzumab mesoo ya.Nnwale ụlọ ọgwụ egosila na Lapatinib na-agwọkwa ndị ọrịa cancer ụdị HER2 nke ọma na nguzogide Herceptin.
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