Lapatinib Intermediate CAS 231278-84-5 Ịdị ọcha>98.0% (HPLC)

Nkọwa dị mkpirikpi:

5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

Nọmba: 231278-84-5

Dị ọcha:> 98.0% (HPLC)

Ọdịdị: Acha odo odo ruo odo odo siri ike ntụ ntụ

Ọkara nke API (CAS 388082-77-7)

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Lapatinib Intermediates:

Lapatinib Base	CAS 231277-92-2
Lapatinib Ditosylate Monohydrate	CAS 388082-78-8
Sodium Methanesulfinate	CAS 20277-69-4
3-Chloro-4- (3-Fluorobenzyloxy) aniline	CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	CAS 16064-08-7
5-Formyl-2-Furanboronic acid	CAS 27329-70-0
5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	CAS 231278-84-5

Njirimara kemịkalụ:

Aha Chemical	5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Ụdị okwu	Lapatinib Intermediate 3;5-[4-[3-Chloro-4-[(3-Fluorophenyl) methoxy] phenyl] amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4- ((3-Chloro-4- ((3-Fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl] -2-Furaldehyde
Nọmba CAS	231278-84-5
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C26H17ClFN3O3
Ibu molekụla	473.90
Ebe Na-agbaze	225.0 ruo 235.0 ℃
Njupụta	1.407±0.06 g/cm3
Ntụgharị uche	1.694
COA & MSDS	Dị
Mmalite	Shanghai, China
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Icha mmirimmiri ruo ntụ ntụ siri ike na-acha odo odo
Ụzọ ịdị ọcha / nyocha	> 98.0% (HPLC)
Ebe Na-agbaze	225.0 ~ 235.0 ℃
Ọnwụ na ihicha	<1.00%
Ihe fọdụrụ na mgbanye	<0.50%
Mgbakọta adịghị ọcha	<2.00%
Ọla dị arọ (dị ka Pb)	<20ppm
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara nke API (CAS 388082-77-7)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

231278-84-5 - Ngwa:

5-[4-[3-Chloro-4- (3-Fluorobenzyloxy) anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) bụ etiti API (CAS 388082-77-7) ).(CAS 388082-77-7) bụ ọgwụ ezubere iche maka ọrịa ara ara nke British GlaxoSmithKline Co. Ọ bụ tyrosine kinase inhibitor nke nwere ike igbochi ọrụ tyrosine kinase nke ọma nke ndị na-anabata ihe na-eto eto epidermal mmadụ 1 na 2 (ErbB1, ErbB2).Ọ nwere ike ime ihe n'ụzọ dị iche iche, na-ahụ na mkpụrụ ndụ kansa ara enweghị ike ịnata akara uto.Ọ na-egbochi intracellular EGFR (ErbB-1) na HER2 (ErbB-2) saịtị ATP, na-egbochi tumor cell phosphorylation na activation, igbochi ala-usoro akara ngosi site homogeneity na heterogeneity nke EGFR (ErbB-1) na HER2 (ErbB-1) dimerization.