CAS 361440-67-7 Ịdị ọcha> Ụlọ ọrụ 98.5% (HPLC)

Nkọwa dị mkpirikpi:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester

Nọmba: 361440-67-7

Dị ọcha:> 98.5% (HPLC)

Ọdịdị: White ntụ ntụ

Ọkara nke API (CAS: 361442-04-8)

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Njirimara kemịkalụ:

Aha Chemical (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester
Ụdị okwu N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate
Nọmba CAS 361440-67-7
Nọmba CAT RF-PI1990
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C11H18N2O3
Ibu molekụla 226.27
Ebe esi nri 388.9 ± 21.0 ℃
Njupụta 1.228
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ọcha ntụ ntụ
Ụzọ ịdị ọcha / nyocha > 98.5% (HPLC)
Ọnwụ na ihicha <0.50%
Ihe fọdụrụ na mgbanye <0.20%
Ihe adịghị ọcha nke onye <1.00%
Mgbakọta adịghị ọcha <1.50%
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ọkara nke API (CAS: 361442-04-8)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

1

Ajụjụ:

Ngwa:

(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) bụ etiti API (CAS: 361442). -04-8).(CAS: 361442-04-8) bụ ọgwụ hypoglycemic ọnụ (ọgwụ mgbochi ọrịa shuga) nke dipeptidyl peptidase-4 (DPP-4) inhibitor klas nke ọgwụ.Ntolite mmalite bụ naanị Bristol-Myers Squibb;na 2007 AstraZeneca sonyeere na Bristol-Myers Squibb iji kwalite ngalaba ikpeazụ na imekọ ihe ọnụ na ire ahịa ọgwụ.Na June 2008, a mara ọkwa na Onglyza ga-abụ aha ahia nke a ga-ere ahịa.A na-eji API (CAS: 361442-04-8) mee ihe dị ka monotherapy ma ọ bụ jikọtara ya na ọgwụ ndị ọzọ maka ọgwụgwọ ụdị ọrịa shuga 2.A na-etinye ya ngwa ngwa mgbe nchịkwa ọnụ gasịrị ma nwee profaịlụ pharmacokinetic dakọtara na otu ugboro kwa ụbọchị.Ọ na-arụ ọrụ a site na igbochi mmebi GLP-l.GLP-I bụ homonụ a na-emepụta na eriri afọ mgbe ọ risịrị nri.

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