CAS 361440-67-7 Ịdị ọcha> Ụlọ ọrụ 98.5% (HPLC)
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Aha Chemical | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester |
Ụdị okwu | N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate |
Nọmba CAS | 361440-67-7 |
Nọmba CAT | RF-PI1990 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C11H18N2O3 |
Ibu molekụla | 226.27 |
Ebe esi nri | 388.9 ± 21.0 ℃ |
Njupụta | 1.228 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ntụ ntụ |
Ụzọ ịdị ọcha / nyocha | > 98.5% (HPLC) |
Ọnwụ na ihicha | <0.50% |
Ihe fọdụrụ na mgbanye | <0.20% |
Ihe adịghị ọcha nke onye | <1.00% |
Mgbakọta adịghị ọcha | <1.50% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke API (CAS: 361442-04-8) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) bụ etiti API (CAS: 361442). -04-8).(CAS: 361442-04-8) bụ ọgwụ hypoglycemic ọnụ (ọgwụ mgbochi ọrịa shuga) nke dipeptidyl peptidase-4 (DPP-4) inhibitor klas nke ọgwụ.Ntolite mmalite bụ naanị Bristol-Myers Squibb;na 2007 AstraZeneca sonyeere na Bristol-Myers Squibb iji kwalite ngalaba ikpeazụ na imekọ ihe ọnụ na ire ahịa ọgwụ.Na June 2008, a mara ọkwa na Onglyza ga-abụ aha ahia nke a ga-ere ahịa.A na-eji API (CAS: 361442-04-8) mee ihe dị ka monotherapy ma ọ bụ jikọtara ya na ọgwụ ndị ọzọ maka ọgwụgwọ ụdị ọrịa shuga 2.A na-etinye ya ngwa ngwa mgbe nchịkwa ọnụ gasịrị ma nwee profaịlụ pharmacokinetic dakọtara na otu ugboro kwa ụbọchị.Ọ na-arụ ọrụ a site na igbochi mmebi GLP-l.GLP-I bụ homonụ a na-emepụta na eriri afọ mgbe ọ risịrị nri.