Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Dị Ọcha>99.0% (HPLC)
Aha Chemical | Lapatinib Ditosylate Monohydrate |
Ụdị okwu | N-[3-chloro-4-[(3-fluorophenyl) methoxy] phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl] quinazolin-4-amine |
Nọmba CAS | 388082-78-8 |
Ọnọdụ Ahịa | Dị na ngwaahịa |
Usoro ihe omimi | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Ibu molekụla | 943.48 |
COA & MSDS | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Icha odo odo ruo odo kristal ntụ ntụ |
Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) |
Ebe Na-agbaze | 240.0 ~ 242.0 ℃ |
Mmiri (KF) | 1.9 ~ 2.4% |
Otu adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.00% |
Ọla dị arọ (dị ka Pb) | ≤20ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API;Maka ọgwụgwọ ndị ọrịa nwere ọrịa ara ara |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) bụ nnu ditosylate.CAS 231277-92-2, ihe sịntetik, quinazoline na-arụ ọrụ ọnụ nwere ọrụ antineoplastic.Ọ na-agbanwe agbanwe na-egbochi phosphorylation nke epidermal growth factor receptor (EGFR), ErbB2, na Erk-1 na-2 na AKT kinases;ọ na-egbochikwa ọkwa protein cyclin D na ahịrị cell tumor mmadụ na xenografts.EGFR na ErbB2 etinyela aka na uto nke ụdị etuto dị iche iche.Emebere ya maka ọgwụgwọ HER2 (ErbB2) dị elu ma ọ bụ metastatic cancer ara na ụmụ nwanyị ndị natara ọgwụgwọ mbụ.GlaxoSmithKline chọtara wee mepụta ọgwụ a.