4,4′-Bis(2-Bromoacetyl)biphenyl CAS 4072-67-7 Daclatasvir Dihydrochloride Intermediate Ọcha>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na-emepụta 4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) na elu mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta 4,4'-Bis(2-Bromoacetyl)biphenyl,Please contact: alvin@ruifuchem.com
| Aha Chemical | 4,4'-Bis (2-Bromoacetyl) biphenyl |
| Ụdị okwu | 4,4'-Bis (Bromoacetyl) biphenyl;1,1'-[1,1'-Biphenyl] -4,4'-diylbis [2-Bromoethan-1-otu];Daclatasvir adịghị ọcha 7 |
| Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
| Nọmba CAS | 4072-67-7 |
| Usoro ihe omimi | C16H12Br2O2 |
| Ibu molekụla | 396.07 g/mol |
| Ebe Na-agbaze | 226.0 ~ 227.0 ℃ |
| Njupụta | 1.622±0.06 g/cm3 |
| COA & MSDS | Dị |
| Mmalite | Shanghai, China |
| Otu | Ọkara nke Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | siri ike | siri ike |
| Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) | 98.5% |
| Spectrum infrared | Nkwekọ na Structure | Na-akwado |
| 1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
| Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
| Ngwa | Ọkara nke Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma debe ya n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na nke ikuku na-ekpo ọkụ n'ebe ihe na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
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Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) bụ etiti nke Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir Dihydrochloride (Daklinza) bụ onye na-egbochi nje ịba ọcha n'anya C (HCV) NS5A nke bara uru na ọgwụgwọ genotype 3 ọrịa ịba ọcha n'anya C na-adịghị ala ala.
Na July 24, 2015, FDA kwadoro ọgwụ ịba ọcha n'anya C na-adịghị ala ala (Bristol-Myers Squibb) maka ịzụ ahịa.
Usoro nnabata FDA nke Daklinza (Bristol-Myers Squibb) emeela ntụgharị na ntụgharị.FDA ajụla ya otu ugboro, mana n'ikpeazụ kwadoro na etiti 2015.FDA kwadoro nchikota Daklinza na Sofosbuvir maka ọgwụgwọ ndị ọrịa ịba ọcha n'anya C ụdị 3.
N'ezie, dị ka tupu nkwado FDA, Daklinza akwadoro maka ịzụ ahịa na Japan, European Union na South Korea na mba ndị ọzọ.Na 2014, ngalaba ahụike Japan kwadoro ngwa nke Daklinza na Asunaprevir (Sunvepra) maka ọgwụgwọ ọrịa genotype 1.European Union kwadoro Daclatasvir ka a na-ejikọta ya na ọgwụ ndị ọzọ na ọgwụgwọ HCV genotypes 1, 2, 3 na 4 na 2014. Daclatasvir bụ nke mbụ NS5A mgbagwoju inhibitor nke European Union (EU) kwadoro.Mgbe ejiri ya na ọgwụ ndị ọzọ, ma e jiri ya tụnyere ọgwụgwọ nke interferon na ribavirin nke na-ewe izu 48, ọ na-ewe obere oge ọgwụgwọ (izu iri na abụọ ma ọ bụ izu iri abụọ na anọ).
A naghị atụ aro daclathavir monotherapy, usoro a bụ isi ugbu a bụ ọgwụgwọ ngwakọta nke Dacastavir + Sofosbuvir, bụ nke e ji arụ ọrụ dị mma, SVR dị elu, obere mmetụta na-ebelata usoro ọgwụgwọ karịa nhọrọ ndị ọzọ.
