Cyproheptadine Hydrochloride Sesquihydrate CAS 41354-29-4 Assay 98.5 ~ 100.5%
Ruifu Chemical bụ onye na-emepụta Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Cyproheptadine Hydrochloride Sesquihydrate,Please contact: alvin@ruifuchem.com
Aha Chemical | Cyproheptadine Hydrochloride Sesquihydrate |
Ụdị okwu | 4- (5H-Dibenzo [a, d] cyclohepten-5-ylidene) -1-methylpiperidine Hydrochloride Sesquihydrate |
Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
Nọmba CAS | 41354-29-4 |
CAS metụtara | 969-33-5 & 129-03-3 |
Usoro ihe omimi | C21H21N·HCl·11/2H2O |
Ibu molekụla | 350.88 g/mol |
Ebe Na-agbaze | 165 ℃ (dc.)(ọkụ) |
Mmiri Solubility | Ihe Na-adịghị Mma Na Mmiri |
Solubility | Soluble nke ukwuu na methanol.Soluble na Chloroform.Na-edozi ntakịrị na ethanol.Na-adịghị edozi na Ether |
COA & MSDS | Dị |
Ihe atụ | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | Ọcha na-acha odo odo kristal ntụ ntụ | Na-akwado |
njirimara | A. Infrared Spectrum kwesịrị ikwekọ | Na-akwado |
B. Kwesịrị Ikwenye | Na-akwado | |
Chromatographic ịdị ọcha | Kwesịrị kwekọrịtara | Na-akwado |
Nyocha | 98.5 ~ 100.5% (gbakọọ na Anhydrous ndabere) | 99.62% |
Mmiri nke Karl Fischer | 7.0 ~ 9.0% | 8.2% |
Ihe fọdụrụ na mgbanye | ≤0.10% | 0.08% |
Acidity | ≤0.15ml | ≤0.13ml |
Ọla dị arọ | ≤10ppm | 8ppm |
Spectrum infrared | Dabara na Ọdịdị | Na-akwado |
Mmechi | Ngwaahịa a site na nyocha kwekọrọ na ọkọlọtọ USP35 | |
Ndụ shelf | Afọ 2 ma ọ bụrụ na echekwara ya nke ọma |
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Cyproheptadine hydrochloride
C21H21N·HCl·1½H2O 350.88
Piperidine, 4- (5H-dibenzo [a, d] cyclohepten-5-ylidene) -1-methyl-, hydrochloride, sesquihydrate.
4- (5H-Dibenzo [a, d] cyclohepten-5-ylidene) -1-methylpiperidine hydrochloride sesquihydrate [41354-29-4].
Anhydrous 323.87 [969-33-5].
Cyproheptadine Hydrochloride nwere ihe na-erughị 98.5 pasent na ọ bụghị ihe karịrị 100.5 pasent nke C21H21N·HCl, gbakọọ na anhydrous ndabere.
Nkwakọ ngwaahịa na nchekwa - Chekwaa n'ime igbe emechiri nke ọma.
Ụkpụrụ ntụaka USP <11>-
USP Cyproheptadine Hydrochloride RS
njirimara-
A: Infrared absorption <197K>.
B: Mmetụta Ultraviolet <197U>-
Ngwọta: 16 μg kwa ml.
Ọkara: mmanya.
Absorptivities na 286 nm adịghị iche karịa 3.0%.
C: igbari 100 mg nke Cyproheptadine Hydrochloride na 10 ml nke methanol.Tinye 1 dobe nke ngwọta n'elu akwụkwọ nzacha, kpoo, ma lelee n'okpuru ìhè UV dị mkpụmkpụ: a na-ahụ ọkụ na-acha anụnụ anụnụ na-egbuke egbuke.
Acidity- Gbari 1.0 g nke Cyproheptadine Hydrochloride na 25 ml nke methanol, tinye methyl red TS, na titrate na 0.10 N sodium hydroxide: ọ bụghị ihe karịrị 0.15 mL achọrọ (0.05% dị ka HCl).
Mmiri, Usoro m <921>: n'etiti 7.0% na 9.0%.
Ihe fọdụrụ na mgbanye <281>: ọ bụghị karịa 0.1%.
Ọla dị arọ, Usoro II <231>: 0.003%.
Assay-gbari ihe dị ka 650 mg nke Cyproheptadine Hydrochloride, nke a tụrụ nke ọma, na 50 ml nke glacial acetic acid, kpo oku ka ọ gbazee.Jụụ, tinye 10 ml nke mercuric acetate TS, 0.5 ml acetic anhydride, na 1 dobe nke crystal violet TS, na titrate na 0.1 N perchloric acid VS na njedebe akwụkwọ ndụ akwụkwọ ndụ.Mee mkpebi efu, ma mee mgbazi ọ bụla dị mkpa.Otu ml nke 0.1 N perchloric acid bụ 32.39 mg nke C21H21N·HCl.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
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Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
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Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
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Ihe akara egwu Xn - na-emerụ ahụ
Koodu ihe egwu
R22 - na-emerụ ma ọ bụrụ na loro ya
R36 / 37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
Nkọwapụta nchekwa
S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36 - Yiri uwe nchebe kwesịrị ekwesị.
NJ UN UN 2811 6.1/PG 3
WGK Germany 3
RTECS TM7050000
Koodu mpaghara:: 2933399011
Klas ihe egwu 6.1
Otu ngwugwu III
Nsi LD50 ọnụ na oke: 74.2 mg/kg (Loux)
Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) bụ ụdị antihistamines pipecolic, ọ nwere ike ịsọ mpi histamine ewepụtara na nzukọ maka ndị na-anabata H1 na mkpụrụ ndụ mmetụta, si otú ahụ ọ nwere ike igbochi mmalite nke mmeghachi ahụ nfụkasị ahụ, wee hapụ histamine- kpalitere spasm na mmetụta nchikota, ngwaahịa a nwere ike na-anabata H1 receptor antagonism, ya antihistamine mmetụta dị ike karịa chlorpheniramine, promethazine.Enwere mmetụta mgbochi serotonin dị nro na nke na-agafeghị oke yana mmetụta anticholinergic.Ke adianade do, e nwere a na-akpali agụụ mmetụta, na ibu ibu mgbe a ụfọdụ oge.
A na-ejikarị Cyproheptadine hydrochloride sesquihydrate eme ihe maka urticaria siri ike na nke na-adịghị ala ala (karịsịa urticaria oyi), papular urticaria, angioedema, nfụkasị ahụ eczema, kọntaktị dermatitis, nri nri, ọgwụ nfụkasị ahụ, nfụkasị rhinitis, hay fever, ihe nfụkasị na conjunctivitis.Ọ nwere mmetụta ọgwụgwọ ụfọdụ na ụkwara ume ọkụ nke bronchi.Enwere ike iji ya maka ọgwụgwọ adjuvant nke Cushing's syndrome na acromegaly.Enwere ike iji ya dị ka ihe nkwalite agụụ maka phobias neurotic.Enwere akụkọ banyere ọgwụgwọ acanthosis nigricans na mgbochi nke necrotizing pyoderma.
Ọrụ na ntinye nke Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4)
1. Cyproheptadine Hydrochloride maka ọgwụgwọ nke urticaria, itching akpụkpọ na nfụkasị rhinitis.
2. Cyproheptadine Hydrochloride bụ ọgwụ ọhụrụ na klas anticoagulant na mgbochi ihe nfụkasị ahụ.Enwere ike iji ya maka mmeghachi omume nfụkasị dị ka urticaria, eczema, allergies na kọntaktị dermatitis na itching.Urticaria, eczema, nfụkasị na kọntaktị dermatitis, pruritus, rhinitis, migraine na bronchial ụkwara ume ọkụ.A na-ejikwa ya maka ọrịa Cushing na acromegaly.
3. Cyproheptadine Hydrochloride bụ ọgwụ na-egbochi ihe nfụkasị ahụ nke na-egbochi omume nke histamine n'ime ahụ na arịa ọbara na ụbụrụ na-egbuke egbuke nke bronchi, si otú a na-ewepụ mgbaàmà nrịanrịa.A na-eji Cyproheptadine hydrochloride maka mmeghachi ahụ nfụkasị dị ka urticaria, eczema, nfụkasị na kọntaktị dermatitis na itching akpụkpọ.