5-Amino-3- (Trifluoromethyl) picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Cleanity>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta 5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6) nke nwere àgwà dị elu, etiti nke Apalutamide (CAS: 956104-40-8).Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Aha Chemical | 5-Amino-3- (Trifluoromethyl) picolinonitrile |
| Ụdị okwu | 5-Amino-3- (Trifluoromethyl) pyridine-2-Carbonitrile;5-Amino-3- (Trifluoromethyl) 2-Cyanopyridine;5-Amino-2-Cyano-3- (Trifluoromethyl) pyridine;Apalutamide adịghị ọcha 10 |
| Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
| Nọmba CAS | 573762-62-6 |
| Usoro ihe omimi | C7H4F3N3 |
| Ibu molekụla | 187.12 g/mol |
| Njupụta | 1.45±0.10 g/cm3 |
| COA & MSDS | Dị |
| Mmalite | Shanghai, China |
| Klas Hazard | 6.1 |
| Otu nkwakọ ngwaahịa | Ⅲ |
| Otu | Ọkara nke Apalutamide (CAS: 956104-40-8) |
| Ụdị | Ruifu Chemical |
| Ihe | Ụkpụrụ nyocha | Nsonaazụ |
| Ọdịdị | Icha odo odo ruo odo siri ike | Na-akwado |
| Mmiri nke Karl Fischer | <0.50% | 0.35% |
| Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) | 99.03% |
| Spectrum infrared | Nkwekọ na Structure | Na-akwado |
| 1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
| Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
| Ngwa | Ọkara nke Apalutamide (CAS: 956104-40-8) | |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma debe ya n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na nke ikuku na-ekpo ọkụ n'ebe ihe na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6), bụ pyridine heterocyclic organic compound, nke enwere ike iji dị ka ndị na-ahụ maka ọgwụ.5-Amino-3- (Trifluoromethyl) picolinonitrile bụ etiti nke Apalutamide (CAS: 956104-40-8).Apalutamide bụ antiandrogen nke ọgbọ nke abụọ ejiri na ọgwụgwọ ọrịa kansa prostate.Ọ bụ onye na-emegide onye na-anabata androgen nwere uru IC50 nke 16 nM.Na-ejikọta ndị na-anabata androgen, si otú a na-egbochi ntụgharị nuklia, njikọ DNA na ịgbalite ederede.Apalutamide nwere ngwa ọgwụgwọ na ọrịa cancer prostate na-abụghị metastatic.
A na-eji Apalutamide agwọ ụfọdụ ụdị ọrịa kansa prostate na-eguzogide castration ma ọ bụ ọrịa kansa prostate na-agbasaghị n'akụkụ ahụ ndị ọzọ, mana ọgwụgwọ ahụike ndị ọzọ enyeghị aka.Apalutamide nọ na klaasị ọgwụ akpọrọ androgen receptor inhibitors.Ọ na-arụ ọrụ site na igbochi mmetụta nke androgen iji kwụsị uto na mgbasa nke mkpụrụ ndụ kansa.Na Septemba 17, 2019, nchịkwa nri na ọgwụ akwadoro Apalutamide (ERLEADA, Janssen Biotech, Inc) maka ndị ọrịa nwere ọrịa kansa prostate metastatic castration-sensitive (mCSPC).A kwadoro Apalutamide na mbụ na 2018 maka ndị ọrịa nwere ọrịa cancer prostate na-abụghị metastatic.
