Enzalutamide CAS 915087-33-1 Ịdị ọcha> 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye nrụpụta nke Enzalutamide (CAS: 915087-33-1) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
Aha Chemical | Enzalutamide |
Ụdị okwu | MDV-3100;MDV 3100;4-[3-[4-Cyano-3- (Trifluoromethyl) phenyl] -5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
Ọnọdụ Ahịa | N'ahịa, Ike nrụpụta 50kgs kwa ọnwa |
Nọmba CAS | 915087-33-1 |
Usoro ihe omimi | C21H16F4N4O2S |
Ibu molekụla | 464.44 g/mol |
Ebe Na-agbaze | 198.0-200.0 ℃ |
Njupụta | 1.49 |
COA & MSDS | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta | Nsonaazụ |
Ọdịdị | Ụtụ siri ike na-acha ọcha ruo na-acha ọcha | Na-akwado |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) | 99.57% |
Mmiri nke Karl Fischer | <0.50% | 0.23% |
Ihe fọdụrụ na mgbanye | <0.10% | 0.06% |
Ọla dị arọ (Pb) | ≤20ppm | <10ppm |
Ihe ndị emetụtara | ||
Oke.Otu adịghị ọcha | <0.50% | <0.50% |
Mgbakọta adịghị ọcha | <1.00% | 0.43% |
Spectrum infrared | Nkwekọ na Structure | Na-akwado |
1H NMR Spectrum | Nkwekọ na Structure | Na-akwado |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe nke ọma na-esi na ihe ndị na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Enzalutamide (CAS: 915087-33-1) bụ onye na-emegide androgen-receptor (AR) na IC50 nke 36 nM, nke na-egbochi androgens site na njikọ nke androgen receptor ma na-egbochi ntugharị nuklia na onye na-arụ ọrụ na-arụ ọrụ nke ligand-receptor complex.E gosikwara Enzalutamide na-ebute apoptosis tumor cell, ma ọ nweghị ọrụ agonist.Enzalutamide bụ onye ndoro-ndoro maka ọgwụgwọ ọrịa kansa prostate na-eguzogide castration.Enzalutamide, bụ onye na-egbochi androgen receptor (AR) nke abụọ.Ọ nwere ike igbochi njikọ nke androgens na AR, ntụgharị nuklia AR, yana njikọ nke AR na DNA.N'August 2012, FDA kwadoro Enzalutamide, nke Medivation na Astellas Pharma US na-ere maka ọgwụgwọ nke ọrịa cancer prostate na-eguzogide metastatic (CRPC), karịsịa maka ndị ọrịa ndị natara Docetaxel na mbụ.