Microcrystalline Cellulose (MCC) CAS 9004-34-6 Assay 97.0 ~ 102.0%

Microcrystalline cellulose
Cellulose [9004-34-6].
Nkọwa
A na-eme ka microcrystalline cellulose dị ọcha, cellulose nke depolymerized nke a kwadebere site n'ịgwọ alfa cellulose, nke enwetara dị ka pulp sitere na ihe ọkụkụ fibrous, nwere acid ịnweta.
Nchọpụta
• A. Usoro
Ihe ngwọta nke zinc chloride nke iodinated: gbazee 20 g nke zinc chloride na 6.5 g nke potassium iodide na 10.5 ml mmiri.Tinye 0,5 g nke ayodiin, ma maa jijiji maka 15 min.
Ihe atụ: 10 mg
Nyocha: Tinye ihe nlele ahụ na iko elekere, wee fesaa na 2 ml nke zinc chloride ngwọta.
Nkwenye nnabata: ihe ahụ na-ewere agba na-acha anụnụ anụnụ-violet.
• B. Usoro
Ihe nlele: 1.3 g nke microcrystalline cellulose, ruru 0.1 mg nke ọma.
Nyocha: Nyefee ihe nlele ahụ na flask conical 125-mL.Tinye 25.0 ml mmiri na 25.0 ml nke 1.0 M cupriethylenediamine hydroxide ngwọta.Ngwa ngwa kpochaa ihe ngwọta na nitrogen, fanye ihe nkwụsịtụ, ma maa jijiji na ihe nkpuchi aka, ma ọ bụ ihe ndị ọzọ na-arụ ọrụ nke ọma, ruo mgbe agbazere kpamkpam.Nyefee olu kwesịrị ekwesị nke ngwọta Sample na nọmba ahazigharịrị 150 Cannon-Fenske, ma ọ bụ ihe dakọtara, viscometer.Kwe ka ihe ngwọta kwekọọ na 25 ± 0.1 maka NLT 5 min.Tinye oge nfe n'etiti akara abụọ na viscometer, wee dekọọ oge erute, t1, na s.
Gbakọọ viscosity kinematic, (KV)1, nke Microcrystalline Cellulose ewepụtara:
Nsonaazụ = t1 × k1
t1 = oge eruba (s)
k1 = viscometer mgbe niile (lee Viscosity 911)
Nweta oge eruba, t2, maka 0.5M cupriethylenediamine hydroxide ngwọta na-eji nọmba 100 Cannon-Fenske, ma ọ bụ ihe kwekọrọ, viscometer.
Gbakọọ viscosity kinematic, (KV)2, nke ihe mgbaze:
Nsonaazụ = t2 × k2
t2 = oge eruba maka 0.5M cupriethylenediamine hydroxide ngwọta (s)
k2 = viscometer mgbe niile
Kpebie viscosity ikwu, rel, nke ụdị Microcrystalline Cellulose ewepụtara:
Nsonaazụ= (KV)1/(KV)2
(KV) 1 = viscosity kinematic nke Microcrystalline Cellulose ewepụtara
(KV) 2 = viscosity kinematic nke ihe mgbaze
Kpebie viscosity dị n'ime, [] c, site na ntinye aka, na-eji Tebụl Viscosity dị n'ime akụkụ nke tebụl ntụaka.
Gbakọọ ogo nke polymerization, P:
Nsonaazụ= (95) × [η]c/WS × [(100%LOD)/100]
[η]c = viscosity dị n'ime
WS = arọ nke Microcrystalline Cellulose weere (g)
% LOD = uru enwetara site na ule maka ọnwụ na nkụ
Usoro nnabata: Ogo nke polymerization agaghị agafe 350.
IHE adịghị ọcha
Ihe adịghị ọcha
• Ihe fọdụrụ na mgbanye 281: NMT 0.1%
• Ọla dị arọ, Usoro II 231: NMT 10 ppm
Nnwale akọwapụtara
• Nnwale ngụkọ microbial 61 na Nnwale maka Microorganisms akọwapụtara 62: Ngụkọta ọnụ ọgụgụ microbial aerobic anaghị agafe 1000 cfu/g, yana mkpokọta agwakọta ebu na yiasts anaghị agafe 100 cfu/g.Ọ na-emezu ihe achọrọ maka ule maka enweghị Staphylococcus aureus na Pseudomonas aeruginosa na enweghị Escherichia coli na ụdị Salmonella.
• Omume
Nlereanya: 5g
Nyocha: Jiri mmiri 40 ml kwagharịa ihe nlele ahụ maka nkeji 20, yana centrifuge.Jide ihe dị elu maka ojiji na nyocha pH.Iji mita conductivity kwesịrị ekwesị nke edoberela na ọkọlọtọ potassium chloride conductivity calibration nwere conductivity nke 100 µS/cm, tụọ conductivity nke supernatant mgbe enwetachara ọgụgụ kwụsiri ike, wee tụọ conductivity nke mmiri eji kwadebe ule ahụ. ihe atụ.
Nkwenye nnabata: Nrụgharị nke igwe anaghị agafe elele mmiri karịa 75µS/cm.
• pH 791: 5.0-7.5 na supernatant enwetara na nyocha omume
• Mfu na ihicha 731: Kpochapụ ihe nlele na 105 maka awa 3: ọ na-efunahụ NMT 7.0% nke ịdị arọ ya, ma ọ bụ ụfọdụ pasent ọzọ dị ala, ma ọ bụ n'ime oke pasent, dị ka akọwapụtara na labeling.
• Nnukwu njupụta
Nyocha: Jiri volumeter etinyere na ihuenyo ntupu 10.The volumeter bụ freestanding nke ọla ma ọ bụ igwe anaghị agba nchara iko, nke a calibrated na ike nke 25.0 ± 0.05 mL na nwere n'ime dayameta nke 30.0 ± 2.0 mm.Tulee iko efu, tinye ya n'okpuru chute, ma jiri nwayọọ nwayọọ wụsa ntụ ntụ site na ịdị elu nke 5.1 cm (2 in) n'elu olulu ahụ site na volumeter, na ọnụego kwesịrị ekwesị iji gbochie clogging, ruo mgbe iko ga-ejupụta.[Rịba ama-Ọ bụrụ na mmechi nke ihuenyo karịrị akarị, wepụ ihuenyo ahụ.] Tinye ntụ ntụ ngafe, ma tụọ iko jupụtara.Gbakọọ nnukwu njupụta site na kewaa arọ nke ntụ ntụ n'ime iko site na olu nke iko.
Usoro nnabata: Nnukwu njupụta dị n'ime nkọwapụta akara.
• Nkesa nha urughuru
[Rịba ama-N'ọnọdụ ebe enweghị nchegbu metụtara ọrụ gbasara nkesa nha akụkọ, enwere ike ịhapụ ule a.]
Ebe labeling na-ekwu na urughuru size nkesa, chọpụta urughuru size nkesa dị ka eduzi na urughuru size nkesa atụmatụ site Analytical Sieving 786, ma ọ bụ site a dabara adaba usoro.
• Ihe na-edozi mmiri
Ihe atụ: 5.0 g
Nyocha: Gwaa ihe nlele ahụ na mmiri 80 ml nke mmiri maka nkeji 10, wee gafere site na enyemaka nke oghere site na akwụkwọ nzacha (Whatman No. 42 ma ọ bụ ihe kwekọrọ) n'ime flask oghere.Nyefee filtrate ahụ na beaker akọrọ, kpochapu na nkụ na-enweghị chaja, kpoo na 105 maka 1 h, dị jụụ na onye na-ekpo ọkụ, ma tụọ.
Ụkpụrụ nnabata: Ọdịiche dị n'etiti ịdị arọ nke ihe fọdụrụ na ịdị arọ enwetara site na mkpebi efu anaghị agafe 12.5 mg (0.25%).
• Ihe ndị na-edozi ahụ
Ihe atụ: 10.0 g
Nyocha: Debe ihe nlele ahụ na kọlụm chromatographic nwere dayameta dị n'ime ihe dịka 20 mm, wee gafere 50 ml nke ether na-enweghị peroxide site na kọlụm.Wepụ eluate ahụ ka ọ kpọọ nkụ n'ime efere a mịrị amị na nke akọrọ na mbụ site n'enyemaka nke ikuku dị ugbu a n'ime mkpuchi uzuzu.Mgbe ether niile kpochara, kpoo ihe fọdụrụ na 105 maka nkeji 30, dị jụụ na onye na-eme ihe, ma tụọ ya.
Usoro nnabata: Ọdịiche dị n'etiti ịdị arọ nke ihe fọdụrụ na ịdị arọ enwetara site na mkpebi efu anaghị agafe 5.0 mg (0.05%).
NKWUO GBASARA YA
• Nkwakọ ngwaahịa na Nchekwa: Chekwaa n'ime akpa siri ike.
• Labeling: Labeling na-egosi mfu n'ọnụ na ihicha, nnukwu njupụta, na ogo nke ụkpụrụ polymerization.A na-ekpebi ogo nke nnabata polymerization site na iji ule njirimara B. Ebe ekwuru na nkesa nha nha nha na akara, gaa n'ihu dị ka eduzi na ule maka nkesa nha nha.Labeling na-egosi na nke usoro nke urughuru size nkesa kpebisiri ike ma ọ bụrụ na a Usoro ọzọ na-abụghị nyocha sieving e ji mee ihe;na akara akara na-egosi ụkpụrụ d10, d50, na d90 yana oke maka nke ọ bụla.