Cetrorelix Acetate CAS 130143-01-0 GnRH Onye na-emegide Peptide Purity (HPLC) ≥98.0% Ogo dị elu
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta Cetrorelix Acetate (CAS: 130143-01-0) nwere àgwà dị elu.Cetrorelix acetate bụ homonụ na-ahapụ gonadotropin (GnRH).Ruifu Chemical na-enye usoro peptides GMP.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Cetrorelix Acetate,Please contact: alvin@ruifuchem.com
Aha Chemical | Cetrorelix acetate |
Ụdị okwu | N-Acetyl-3- (2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate |
Usoro | Ac-3- (2-naphthyl) -D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2 |
Nọmba CAS | 130143-01-0 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Kilogram |
Usoro ihe omimi | C70H92N17O14 |
Ibu molekụla | 1551.16 |
Okpomọkụ nchekwa. | Ebe dị jụụ na akọrọ (-20 ℃).Igwe nju oyi |
Ndụ shelf | > Afọ 2 ma ọ bụrụ na echekwara ya nke ọma |
Otu | GMP Peptides |
Akwụkwọ | COA, MS, HPLC, NMR, MSDS, wdg. |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ntụ ntụ |
Peptide dị ọcha (nke HPLC) | ≥98.0% (site na Njikọ Mpaghara) |
Ọdịnaya Peptide | ≥80.0% (site na %N) |
Amino acid mejupụtara | 10% nke Theetical |
Ọdịnaya Acetate | ≤10.0% (nke HPLC) |
Ọdịnaya TFA | ≤1.0% |
Otu adịghị ọcha | ≤1.0% (nke HPLC) |
Ọdịnaya Mmiri (Karl Fischer) | ≤8.0% |
Nyocha | 95.0 ~ 105.0% (Site na Anhydrous, Acetic Acid-Free) |
MS | Na-agbanwe agbanwe |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Achọrọ mbupu | Akpa ice, akpa agwụcha |
Mmalite nke ngwaahịa | sịntetik |
Nlebara anya | Naanị maka nyocha, ọ bụghị maka ojiji mmadụ |
Ojiji | Synthetic antagonist nke GnRH Nnabata |
ngwugwu:Plastic vial (raara onwe ya nye maka mbukota peptide) ma ọ bụ vial iko, ọnụọgụ dị ka nkọwa ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mkpuchi mkpuchi n'ụlọ nkwakọba ihe dị jụụ na nkụ (2 ~ 8 ℃) pụọ na ihe ndị na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Nyefee n'ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Cetrorelix Acetate (CAS 130143-01-0) bụ onye na-emegide gonadotropin na-ahapụ homonụ (GnRH) nke a na-ere ahịa bụ isi n'okpuru aha aha Cetrotide.A na-eji decapeptide sịntetik, nke a na-eji ya na mmeputakwa enyere aka igbochi mmụba nke homonụ luteinizing.Ọgwụ a na-arụ ọrụ site na igbochi ọrụ GnRH na pituitary, si otú a na-egbochi mmepụta na mmepụta nke hormone luteinizing (LH) na hormone na-akpali akpali (FSH).Cetrorelix Acetate bụ ihe mejupụtara amino acid dị iche iche na-abụghị nke okike nke na-egbochi ovulation n'oge na ule ụlọ ọgwụ, na-eduga na nchịkọta ovulation na enyemaka nkà na ụzụ na-enye aka maka ndị ọrịa na-enwe mkpali ovarian a na-achịkwa.
Ngosipụta Cetrorelix Acetate bụ homonụ arụrụ arụ nke na-egbochi mmetụta nke homonụ na-ahapụ gonadotropin (GnRH).Na teknụzụ ịmụ nwa na-enyere aka, na ndị ọrịa nwere mkpali ovarian a na-achịkwa, na-egbochi ovulation akaghi aka.
Ọrụ ọgwụ Cetrorelix Acetate bụ onye na-emegide gonadotropin na-ahapụ homonụ (GnRH).GnRH nwere ike jikọta na ndị na-anabata membrane nke sel pituitary.Cetrorelix acetate na-ejikọ aka na ndị nnabata ndị a nwere GnRH endogenous, si otú a na-egbochi ọgwụ na-egbochi secretion nke luteinizing hormone (LH) na follicle stimulating hormone (FSH) site na adenohypophysis.Emepụtara mmetụta mgbochi ozugbo mgbe nchịkwa nke cetrorelix acetate gasịrị, a pụkwara ịnọgide na-enwe mmetụta mgbochi site na ọgwụgwọ na-aga n'ihu.maka ụmụ nwanyị, Cetrorelix Acetate nwere ike igbu oge elu LH, si otú a na-egbu oge ovulation.Maka ụmụ nwanyị na-enwe mkpali ovarian, oge a na-eme ihe na-adabere na dose.A na-eme atụmatụ na otu dose nke cetrorelix 3mg nwere mmetụta mgbochi nke ọ dịkarịa ala 4 ụbọchị, na-enwe mmetụta mgbochi nke ihe dịka 70% na Ụbọchị 4. Nlekọta ugboro ugboro nke cetrorelix acetate 0.25mg kwa awa 24 nwere ike ịnọgide na-enwe mmetụta ya.Mmetụta na-emegide homonụ nke Cetrorelix Acetate gbanwere kpamkpam na njedebe ọgwụgwọ na anụmanụ na ụmụ mmadụ.
Ọrụ ndu Cetrorelix Acetate bụ onye na-emegide GnRH nwere uru IC50 nke 1.21 nM.
Ebumnuche IC50: 1.21 nM GnRH.