Cisatracurium Besylate CAS 96946-42-8 Assay 95.0%~102.0% API Ụlọ ọrụ dị elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha Chemical: Cisatracurium Besylate
CAS: 96946-42-8
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Cisatracurium Besylate |
Nọmba CAS | 96946-42-8 |
Nọmba CAT | RF-API13 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C53H72N2O12.2C6H5O3S |
Ibu molekụla | 1243.49 |
Ebe Na-agbaze | 90.0 ~ 93.0 ℃ |
Ọnọdụ mbupu | N'okpuru ọnọdụ okpomọkụ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ na-acha ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ọcha, enweghị isi, obere hygroscopic |
Solubility | Na-agbaze kpamkpam na dichloromethane, acetonitrile, ntakịrị soluble na mmiri |
Ntụgharị akọwapụtara | -35.0° ka -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
njirimara | Gbarie na dilute hydrochoric acid, dropwise itughari bismuth potassium iodide TS, a ga-emepụta mmiri ozuzo odo. |
njirimara | 1. HPLC ;2. IR |
Nyocha | 95.0 ~ 102.0% (C65H82N2O18S2 na ntọala a mịrị amị) |
pH | 3.5 ruo 5.0 |
Dozie & Agba nke Ngwọta | Kwesịrị ịdị ọcha & enweghị agba |
Ọnwụ na ihicha | ≤2.0% |
Mwepu na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Trans-Trans Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Mono-quaternary | ≤1.50% |
Ọdịghị ọcha nke Onwe Onye ọzọ | ≤1.50% |
Mgbakọta adịghị ọcha | ≤5.0% |
Ngwa anya Isomer SS-Isomer | ≤1.50% |
Ngwa anya Isomer RS- Isomer | ≤1.00% |
Sulfate | ≤50ppm |
Ethyl | ≤0.50% |
Acetone | ≤0.50% |
Methanol | ≤0.3% |
Dichloromethane | ≤0.06% |
Acetonitrile | ≤0.041% |
Methylbenzene | ≤0.089% |
Acetonitrile fọdụrụnụ | ≤410ppm |
Nlele ọkọlọtọ | Ndị China Pharmacopoeia (CP) |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Cisatracurium Besylate (CAS 96946-42-8) bụ nnu benzene sulfonate ụdị atracurium.Ọ bụ ụdị ihe na-eme ka ahụ ike na-eme ihe na-adịghị emebi emebi na ọrụ ya dị ka tubocurarine.Usoro ọgwụgwọ anaghị emetụta ọrụ obi, imeju na akụrụ.O nweghikwa ihe nchikota.Ọ nwekwara ike ịkpalite ntọhapụ nke histamine mgbe ejiri ya na nnukwu doses.Maka izu ike nke anụ ahụ ma ọ bụ njikwa iku ume chọrọ n'ịwa ahụ, ma e jiri ya tụnyere ọgwụ anestetiiki bụ isi akwara na-eme ka ahụ dị jụụ, cisatracurium besylate adịghị metabolized site na imeju ma ọ bụ akụrụ, ma nwee nkwụsi ike nke obi;Mmetụta ya nke ntụrụndụ anụ ahụ bụ ugboro 3 siri ike dị ka atracurium na-enweghị mmetụta ọ bụla nke obi.A na-etinye Cisatracurium besylate n'ụzọ zuru oke na mgbakasị izugbe, a pụkwara iji ya mee ihe na intubation, na-agwọ ọrịa imeju na akụrụ, nke a na-eji na ịwa ahụ obi na ndị agadi na ndị ọrịa ụmụaka.E jiri ya tụnyere atracurium, ngwaahịa a enweghị mmetụta ọjọọ na-adabere na dose nke ntọhapụ histamine;Otú ọ dị, mwepu bụ na ndị ọrịa nwere imeju na akụrụ adịghị arụ ọrụ kwesịrị iji nlezianya mee ihe.Ebe ọ bụ na 1996 maka oge mbụ mgbe ọgwụ a batara n'ahịa na UK, mba ndị ọzọ ejirila nwayọọ nwayọọ tinye ya iji dochie vecuronium na atracurium dị ka isi ihe na-eme ka ahụ ike na-ahụ maka ahụike.