Cyano-Irbesartan CAS 138401-24-8 Ịdị ọcha>98.0% (HPLC) Ụlọ ọrụ etiti Irbesartan
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tritil Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Aha Chemical | Cyano-Irbesartan |
Ụdị okwu | CyanoIrbesartan;Irbesartan Cyano adịghị ọcha;Irbesartan hydrocarbon;Irbesartan adịghị ọcha 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl] -4-yl]methyl] -1,3-diazaspiro [4,4] na-abụghị 1-en-4-otu;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4] na-abụghị 1-en-3-yl) methyl]-[1,1'-biphenyl]-2-carbonitrile |
Nọmba CAS | 138401-24-8 |
Nọmba CAT | RF-PI1892 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C25H27N3O |
Ibu molekụla | 385.51 |
Njupụta | 1.15 |
Solubility (Na-agbaze na) | Methanol |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha ntụ ntụ ka kristal |
Ụzọ ịdị ọcha / nyocha | > 98.0% (HPLC) |
Ịdị ọcha | > 97.0% (yana ngụkọta nitrogen) |
Ebe Na-agbaze | 91.0 ruo 95.0 ℃ |
Ọnwụ na ihicha | <1.00% |
Otu adịghị ọcha | <1.00% |
Ọla dị arọ | <20ppm |
Spectrum infrared | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara/adịghị ọcha nke Irbesartan (CAS: 138402-11-6) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Cyano-Irbesartan (CAS: 138401-24-8) bụ etiti ma ọ bụ adịghị ọcha nke Irbesartan (CAS: 138402-11-6).Irbesartan bụ ihe mgbochi angiotensin II (Angiotensin II, Ang II).A na-ekewa ndị na-anabata Angiotensin II ụzọ abụọ: AT1 na AT2.Irbesartan na-ahọrọ nke ọma igbochi AT1 nnabata nke Angli.Ọ nwere ike igbochi ntụgharị nke Ang n'ime Ang, nwere ike imegide onye na-anabata angiotensin na-agbanwe enzyme 1 (AT1).Mmetụta mmegide na AT1 bụ ugboro 8500 karịa nke AT2.Ọ nwere ike họrọ igbochi njikọ nke Ang na AT1 receptor site Inhibit vasoconstriction na ntọhapụ nke aldosterone, na-ebute mmetụta hypotensive.Ngwaahịa a anaghị egbochi angiotensin na-agbanwe enzyme (ACE), renin, ndị na-anabata homonụ ndị ọzọ, ma ọ bụ na-egbochi ọwa ion metụtara ụkpụrụ mgbali ọbara na nguzozi sodium.Irbesartan nwekwara ike ibelata ngbanwe eletriki nke myocardium, si otú a na-ebelata ọnụ ọgụgụ ọnwụ nke ndị ọrịa nwere ọbara mgbali elu.Ugbu a ọ bụ ọgwụ kachasị dị irè maka ọgwụgwọ ọbara mgbali elu na ọrịa obi.