Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) ihe enyemaka ọgwụ.
Ruifu Chemical bụ onye na-emepụta Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com
Aha Chemical | Hydroxypropyl-β-Cyclodextrin |
Ụdị okwu | Cyclodextrin HPB;Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl) -beta-Cyclodextrin;beta-Hydroxypropylcyclodextrin;HBC;HPBCD;HP-β-CD |
Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
Nọmba CAS | 128446-35-5 |
Usoro ihe omimi | C63H112O42 |
Ibu molekụla | 1541.54 g/mol |
Ebe Na-agbaze | 262.0 ~ 269.0 ℃ |
Njupụta | 1.05 |
Ntụgharị a kapịrị ọnụ [a]20/D | +120° ruo +135° (C=1, H2O) |
Mmiri Solubility | Soluble na Mmiri |
COA & MSDS | Dị |
Nlereanya efu | Dị |
Mmalite | Shanghai, China |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta | Nsonaazụ |
Ọdịdị | Ọcha ntụ ntụ, Insipid, aka ọjọọ | Dabara |
IR Spectrum | Otu eriri absorption nwere USP Hydroxypropyl Betadex RS | Dabara |
pH | 5.0-7.5 | 6.57 |
Ngwọta doo anya | Ngwọta doro anya na enweghị agba | Dabara |
Ọnwụ na ihicha | ≤10.0% | 3.5% |
Ihe fọdụrụ na mgbanye | ≤0.20% | 0.09% |
Ọla dị arọ | ≤20ppm | <10ppm |
Chloride | ≤0.05% | <0.05% |
Ngbanwe Molar | 0.4-1.5 | 0.63 |
Omume omume | 10% (w/v) Ngwọta mmiri ≤200μS/cm | 154µS/cm |
Ọkwa nke nnọchi | 2.8-10.5 | 5.3 |
Ihe fọdụrụ Betadex | ≤1.50% | 0.12% |
Propylene glycol | ≤2.50% | 0.29% |
Propylene oxide | ≤1pm | <1pm |
Ọdịghị ọcha ọ bụla ọzọ | ≤0.25% | <0.25% |
Nchikota nke adịghị ọcha ndị ọzọ | ≤1.00% (Ewezuga Betadex na Propylen Glycol) | 0.51% |
TAMC | ≤1000cfu/g | 30cfu/g |
TYMC | ≤100cfu/g | 10cfu/g |
Escherichia Coli | Enweghị ike ịchọpụta | Dabara |
Salmonella | Adịghị | Adịghị |
Endotoxins nke nje bacteria | <10IU/g | <10IU/g |
Mmechi | Nlele ma na-akwado ọkọlọtọ USP35 |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe akpa ahụ nke ọma ma debe ya n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na nke ikuku na-ekpo ọkụ n'ebe ihe na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.Ekwekọrịtaghị na ndị ọrụ oxidizing siri ike.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Nkọwapụta nchekwa | 24/25 - Zere kọntaktị na akpụkpọ ahụ na anya. |
WGK Germany | 3 |
RTECS | GU2293332 |
Koodu HS | 3505100000 |
Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) bụ cyclodextrin a na-agbanwe n'ọtụtụ ebe, oghere lipophilic guzobere site na nkeji glucose 7.A na-eme ka mmiri ọgwụ ike dị n'ime mmiri dịkwuo mma site na iji HP-β-CD gbakọta.Ihe mkpuchi ime, usoro ntọhapụ na-adịgide adịgide, buccal na nnyefe ọgwụ transdermal.
Hydroxypropyl-β-Cyclodextrin, ihe mmepụta nke hydroxyalkyl, na-achọta ngwa dị ka ụgbọ nhazi nke a na-eji eme ka solubility nke ọgwụ ahụ dị na ngwọta mmiri maka nnyefe nke ọma nke ndị ọrụ ahụike na usoro ndu.A na-arụkarị ya n'ọrụ ka ọ nọchiri anya α-, β- na γ-Cyclodextrins.
Hydroxypropyl betadex enyochala nke ọma na ọgwụ ọgwụ wee jiri ya mee ihe dị ka solubilizer maka ụmụ irighiri mmiri hydrophobic n'ime mmiri ọnụ, ihe siri ike ọnụ, parenterals, ndị na-eku ume metered nke nrụgide, ndị na-ekpo ọkụ ntụ ntụ, na usoro nhazi.E gosikwara na ọ na-eme ihe dị ka ihe nkwụsi ike n'oge nhazi na nchekwa nke usoro.Mgbakọ gụnyere Hydroxypropyl betadex ka akọpụtala ka ọ gosipụta ihe eji arụ ọrụ dị iche na ihe dị ọcha.Uru a kọrọ na hydroxypropyl betadex n'elu b-cyclodextrin na-edochighi ya bụ nnukwu mmiri solubility ya.
1. Solubilization na solubilization, na-eme ka ọgwụ ndị na-adịghị edozi ahụ gbazee, melite solubility nke ihe ndị na-arụ ọrụ nke ọgwụ mmanu mmanu, nnyefe ọgwụ na-echekwa ma chebe ịdị irè nke ọgwụ ọgwụ.
2. Meziwanye bioavailability nke ọgwụ, mụbaa mmetụta ọgwụgwọ nke ọgwụ ma ọ bụ belata usoro onunu ogwu.
3. Gbanwee ma ọ bụ chịkwaa ọnụego ntọhapụ nke ọgwụ iji belata mmetụta ndị ahụ.
4. Na-ekpuchi isi ísì ọjọọ.
1) Na ọgwụ ubi,
1. Hydroxypropyl Beta Cyclodextrin nwere ike ịbawanye solubility nke ọgwụ na ihe dị ndụ, tinyekwa mmetụta dị mma ma belata dose ahụ.
2. HP-β-CD nwere ike ijikwa ma ọ bụ gbanwee ngwa ngwa mmeghachi omume, belata nsị ọgwụ ma welie nkwụsi ike nke ọgwụ.
3. Ezigbo solubilizer injection na ihe ndị na-emepụta ọgwụ n'ihi ọrụ ala dị ala na ọrụ hemolytic, ọ dịghị mkpasu iwe.
4. A naghị eji HP-β-CD mee ihe na ọgwụ ọnụ, injection, usoro nnyefe ọgwụ mucosal, usoro nnyefe ọgwụ transdermal, lipotropy ezubere iche na-ebu ọgwụ, ma enwere ike iji ya dị ka onye na-echebe protein na stabilizer.
5. Iji melite organoleptic Njirimara nke ilu ma ọ bụ wetara Actives.
2) N'ubi nri,
1. HP-β-CD nwere ike igbochi evaporation nke obodo bekee ịnọgide na-enwe nkwụsi ike nke ya nri, tufuo nke egwu isi na ike budata welie mmetụta nke emulsification na jikọtara ojiji nke nri emulsifiers.
2. HP-β-CD nwekwara ike ime ka nchekwa nri ntọhapụ nwayọọ nwayọọ, bulie mmetụta nke mgbochi corrosion na ịgbatị ndụ shelf nke nri.
3) Na ụlọ ọrụ ịchọ mma
1. Na ihe ịchọ mma akụrụngwa eji eme ihe dị ka stabilizer, emulsifier, solubilizer wdg.
2. HP-β-CD nwere ike ibelata mkpali na akpụkpọ ahụ, ma welie nkwụsi ike nke ihe ndị dị irè
3. HP-β-CD nwere ike ibelata ma ọ bụ kpuchie isi ọjọọ nke ihe oriri na-edozi ahụ.
4. Gbochie nri mejupụtara nke na-agbanwe agbanwe, oxidation, mụbaa infusibility, ihe kacha mkpa, ihe na-esi ísì ụtọ nke mmiri na-edozi ma mee ka ísì ahụ dị ngwa ngwa ma na-adịgide adịgide.