Docetaxel CAS 114977-28-5 Assay 98.0% ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta Docetaxel (Taxotere) (CAS: 114977-28-5) nwere oke mma.Ruifu Chemical nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, ọrụ magburu onwe ya, obere na nnukwu ọnụọgụ dị.Ịzụta Docetaxel,Please contact: alvin@ruifuchem.com
| Aha Chemical | Docetaxel |
| Ụdị okwu | Taxotere;Taxotere Anhydrous;Docetaxel Anhydrous;N-Debenzoyl-N-tert-Butoxycarbonyl-10-Deacetyltaxol;RP-56976 |
| Ọnọdụ Ahịa | Na ngwaahịa, Mmepụta Azụmahịa |
| Nọmba CAS | 114977-28-5 |
| Usoro ihe omimi | C43H53NO14 |
| Ibu molekụla | 807.89 g/mol |
| Ebe Na-agbaze | 186.0 ~ 192.0 ℃ (Dec.) |
| Njupụta | 1.38 |
| Solubility | Soluble nke ukwuu na acetone, Dimethylformamide.Soluble na ethanol, Dichloromethane, methanol.Na-adịghị edozi n'ime mmiri |
| COA & MSDS | Dị |
| Mmalite | Shanghai, China |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | White Crystalline ntụ ntụ | White Crystalline ntụ ntụ |
| njirimara | IR & HPLC | Dabara |
| Ntụgharị a kapịrị ọnụ [a]20/D | -42.0° ruo -45.0° (C=1 na EtOH) | -43.1° |
| Ọnwụ na ihicha | <3.00% | 2.05% |
| Ihe fọdụrụ na mgbanye | <0.10% | 0.04% |
| Ọla dị arọ (Pb) | ≤20ppm | <20ppm |
| Arsenic (dị ka) | ≤1.5pm | <1.5pm |
| Ihe ndị emetụtara | ||
| Oke adịghị ọcha otu | <0.50% | <0.50% |
| Mgbakọta adịghị ọcha | <1.00% | <1.00% |
| Nnwale oke microbial | ||
| TAMC | ≤100cfu/g | <100cfu/g |
| TYMC | ≤10cfu/g | <10cfu/g |
| Endotoxins nke nje bacteria | ≤0.3IU/mg | <0.3IU/mg |
| Usoro nyocha / nyocha | 98.0% ~ 102.0% (Na ihe mgbaze na-enweghị ihe mgbaze) | 100.9% |
| Mmechi | A nwalela ngwaahịa a wee kwado nkọwa ndị enyere | |
ngwugwu:Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Nchekwa:Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ, kpọrọ nkụ (2 ~ 8 ℃) yana ụlọ nkwakọba ihe nke ọma na-esi na ihe ndị na-adabaghị adaba.Chebe site na ìhè na mmiri mmiri.Ekwekọrịtaghị na ndị ọrụ oxidizing siri ike.
Mbupu:Jiri ikuku na-ebuga ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Ihe akara egwu Xi - iwe
Koodu ihe egwu
R36 / 37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
R61 - nwere ike imerụ nwa e bu n'afọ
Nkọwapụta nchekwa
S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36/37 - Yiri uwe nchebe kwesịrị ekwesị na uwe aka.
S53 - Zere ikpughe - nweta ntuziaka pụrụ iche tupu ejiri ya.
S45 - Ọ bụrụ na ihe mberede ma ọ bụ ọ bụrụ na ahụ adịghị gị mma, chọọ ndụmọdụ ahụike ozugbo (gosi akara ahụ mgbe ọ bụla enwere ike.)
UN ID 1544
WGK Germany 3
RTECS DA4172750
Koodu HS 2932999029
Klas 6.1 (b) egwu
Otu ngwugwu III
Nsí LD50 eriri afọ n'ime nkịta: 2500ug/kg
Docetaxel (Taxotere) (CAS: 114977-28-5) rere dị ka Taxotere ma ọ bụ Docecad, bụ ọgwụ mgbochi mitotic chemotherapy nke ọma nke na-arụ ọrụ site na itinye aka na nkewa sel.Docetaxel bụ FDA kwadoro maka ọgwụgwọ ọrịa kansa ara dị elu nke mpaghara ma ọ bụ metastatic, kansa isi na olu, ọrịa kansa afọ, ọrịa kansa prostate na-egbochi homonụ na ọrịa cancer akpa ume na-abụghị obere cell.Enwere ike iji Docetaxel dị ka otu onye nnọchi anya ma ọ bụ jikọtara ya na ọgwụ chemotherapeutic ndị ọzọ dị ka egosiri dabere na ụdị ọrịa kansa na ogbo.Docetaxel bụ onye so na klaasị ọgwụ mgbochi, nke gụnyekwara paclitaxel ọgwụ chemotherapeutic.Ọ bụ ezie na docetaxel na-anọgide na-enwe ike okpukpu abụọ ka paclitaxel (n'ihi mmetụta docetaxel na centrosome nke spindle mitotic), a na-ahụta ụtụ isi abụọ ahụ ka ha na-arụ ọrụ nke ọma.Ọtụtụ akụkọ na-adịbeghị anya achọpụtala "ọ dịghị ihe àmà na-egosi na usoro ndị nwere docetaxel na-enye uru dị ukwuu karịa ndị gụnyere paclitaxel."Ọ bụ ezie na ahụrụ ịdị irè n'etiti ndị ọrụ abụọ ahụ ka ha nhata, paclitaxel nwere ike ịkpata mmetụta dị ntakịrị.Na mgbakwunye, a chọpụtala na docetaxel na-enwe ike iguzogide ọgwụ cellular site na usoro dị iche iche dị iche iche.
1. Docetaxel bụ ọgwụ mgbochi mitotic chemotherapy nke ọma (ya bụ, ọ na-egbochi nkewa cell).
2. A na-eji Docetaxel tumadi maka ọgwụgwọ ara, ovarian, na ọrịa cancer akpa ume na-abụghị obere cell.
3. Docetaxel nwere akwụkwọ FDA kwadoro maka ọgwụgwọ nke ndị ọrịa nwere ọganihu na mpaghara, ma ọ bụ ara metastatic ma ọ bụ ọrịa cancer akpa ume na-abụghị obere cell bụ ndị meworo ọgwụ chemotherapy dabeere na anthracycline ma kwụsị ịkwụsị ọrịa cancer ma ọ bụ nlọghachi azụ.Doce-taxel nkwado nke Europe maka ojiji na ọrịa kansa prostate na-egbochi homonụ.
4. A na-ewere Docetaxel dị mma karịa , dị ka cytotoxic antimicrotubule.
