Entecavir CAS 142217-69-4 API Mgbochi HBV dị elu

Nkọwa dị mkpirikpi:

Aha: Entecavir

OZI: 142217-69-4

Ọdịdị: White Crystalline ntụ ntụ

A na-eji ọgwụ mgbochi nje na-agwọ ọrịa ịba ọcha n'anya B

API Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Onye nrụpụta nwere ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Entecavir
OZI: 142217-69-4
A na-eji ọgwụ mgbochi nje na-agwọ ọrịa ịba ọcha n'anya B
API Ogo dị elu, mmepụta azụmahịa

Njirimara kemịkalụ:

Aha Chemical Entecavir
Ụdị okwu 2-Amino-1,9-dihydro-9-[(1S,3R,4S) -4-hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl]-6H-purin-6-otu.
Nọmba CAS 142217-69-4
Nọmba CAT RF-API80
Ọnọdụ Ahịa Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi C12H15N5O3
Ibu molekụla 277.28
Ebe Na-agbaze 249.0 ~ 252.0 ℃
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị White Crystalline ntụ ntụ
njirimara IR Ụdị nnabata infraed nke nlele ule ga-adarịrịrịrị na ọkọlọtọ ntụaka
njirimara HPLC Oge njide nke nlele ule dabara na nke ọkọlọtọ ntụaka
pH 5.5-7.5
Ntụgharị ngwa anya akọwapụtara +24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Ihe ndị emetụtara
Mgbakọta adịghị ọcha ≤0.30%
Oke adịghị ọcha otu ≤0.10%
Entiomer ≤0.20%
Ihe mgbaze fọdụrụnụ
Methanol ≤0.30%
Dichloromethane ≤0.06%
n-Hexane ≤0.029%
Tetrahydrofuran ≤0.072%
N, N-Dimethylformamide ≤0.088%
Toluene ≤0.089%
Ọdịnaya Mmiri 5.8% ~ 6.5%
Ihe fọdụrụ na mgbanye ≤0.10%
Ọla dị arọ ≤20ppm
Nyocha 98.0% ~ 102.0% (C12H15N5O3 gbakọọ na anhydrous ndabere)
Nha urughuru D90: ≤100µm
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji API, ọgwụ mgbochi nje ejiri na ọgwụgwọ ọrịa ịba ọcha n'anya B

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

1

Ajụjụ:

Ngwa:

Entecavir bụ ọgbọ ọhụrụ nke guanine nucleoside analogues ọgwụ ọnụ maka ọgwụgwọ ọrịa ịba ọcha n'anya B (HBV), tumadi maka ọgwụgwọ nke ndị okenye nwere ọrịa viral replication na serum transaminase nọgidere na-abawanye, ma ọ bụ imeju anụ ahụ maka pathological ọrụ nke na-adịghị ala ala ịba ọcha n'anya B. , ugbu a bụ nje virus kacha ọsọ na nke kachasị ike, ọnụọgụ nucleoside kacha ala.Data na-egosi na dị iche iche na ndị ọrịa na-adịghị ala ala ịba ọcha n'anya B, gụnyere nucleoside naive na nucleoside mesoo na imeju cirrhosis ọrịa, na-eji nke ọma mbadamba entecavir na ọgwụgwọ nwere ike ịchịkwa ọrịa ngwa ngwa na mfe iru ọgwụgwọ nke eziokwu ọgwụgwụ, ya bụ nje ịba ọcha n'anya B enweghị atụ;site na nrubeisi na ọgwụgwọ, a bukwanu akụkụ nke ndị ọrịa nwere ike bịarute na njedebe nke ọgwụgwọ afọ ojuju, ya bụ e antigen serology ntughari, ụfọdụ ndị ọrịa nwere ike ọbụna iru mma maka ọgwụgwọ nke ọgwụgwụ, ya bụ elu antigen ọjọọ.

Dee ozi gị ebe a ziga anyị ya