Etravirine TMC-125 CAS 269055-15-4 Assay ≥99.0% (HPLC) API Ụlọ ọrụ dị ọcha
Onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha Chemical: EtravirineTMC-125)
CAS: 269055-15-4
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Etravirine |
Ụdị okwu | TMC-125 |
Nọmba CAS | 269055-15-4 |
Nọmba CAT | RF-API54 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C20H15BrN6O |
Ibu molekụla | 435.28 |
Njupụta | 1.439 g/cm3 |
Ọnọdụ mbupu | N'okpuru ọnọdụ okpomọkụ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha siri ike ntụ ntụ |
njirimara | Site na IR, HPLC |
Ebe Na-agbaze | 211.0 ~ 216.0 ℃ |
Ọdịnaya Mmiri | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Ọdịghị ọcha ọ bụla | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Nyocha | ≥99.0% (HPLC) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
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Etravirine (TMC-125) (CAS 269055-15-4) bụ ọgbọ nke abụọ na-abụghị nucleoside reverse transcriptase inhibitor (NNRTI) eji maka ọgwụgwọ HIV.A na-egosi ya maka iji ya na ihe ndị ọzọ na-egbochi nje HIV maka ịgwọ nje HIV-1 na ndị okenye nwere ahụmahụ ọgwụgwọ nwere ihe akaebe nke nje virus na nje HIV-1 na-eguzogide ọgwụ NNRTI dị ugbu a na ndị ọzọ na-ahụ maka ọgwụ nje.NNRTIs, yana nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs), bụ akụkụ dị mkpa nke usoro nchikota eji eme ugbu a iji gwọọ nje HIV-1.NRTIs/NtRTIs na-eme ihe site na ịsọ mpi nucleotide sitere n'okike nke reverse transcriptase maka ntinye n'ime DNA viral na nkwụsị agbụ na-esote.N'ụzọ dị iche, NNRTIs na-ejikọta na saịtị allosteric nke enzyme ahụ ma mebie ọrụ DNA polymerase site na ime mgbanwe mgbanwe na saịtị catalytic.
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