Ezetimibe CAS 163222-33-1 Ịdị ọcha 98.5%~102.0% (HPLC) API High Purity
Onye nrụpụta;Ogo dị elu na ọnụ ahịa asọmpi
Azụmahịa Ezetimibe (CAS: 163222-33-1) Ndị na-emekọrịta ihe:
(S)-(+)-4-Phenyl-2-oxazolidinone CAS: 99395-88-7
(R)-(+)-2-Methyl-CBS-oxazaborolidine CAS: 112022-83-0
4- (4-Fluorobenzoyl) butyric acid CAS: 149437-76-3
4-[[(4-Fluorophenyl) imino]methyl] -phenol CAS: 3382-63-6
N- (4- (Benzyloxy) benzylidene) -4-fluoroaniline CAS: 70627-52-0
(3R,4S) -4-[4- (Benzyloxy) phenyl] -1- (4-fluorophenyl) -3- [3- (4-fluorophenyl) -3-oxopropyl] azetidin-2-otu CAS 190595-65- 4
(4S) -3- [5- (4-Fluorophenyl) -1,5-dioxopenyl] -4-phenyl-2-oxazolidinone CAS: 189028-93-1
(4S) -3- [(5S) -5- (4-Fluorophenyl) -5-hydroxypentanoyl] -4-phenyl-1,3-oxazolidin-2-otu CAS: 189028-95-3
Ezetimibe CAS: 163222-33-1
Aha Chemical | (3R,4S) -1- (4-Fluorophenyl) -3- [(S) -3- (4-fluorophenyl) -3-hydroxypropyl] -4- (4-hydroxyphenyl)zetidin-2-otu |
Ụdị okwu | Ezetimibe |
Nọmba CAS | 163222-33-1 |
Nọmba CAT | RF-API02 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
Usoro ihe omimi | C24H21F2NO3 |
Ibu molekụla | 409.43 |
Ebe Na-agbaze | 162.0 ~ 166.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
njirimara | Site na IR, HPLC |
Ụzọ ịdị ọcha / nyocha | 98.5% ~ 102.0% (HPLC) |
Ntụgharị akọwapụtara | -25.0° ~ -30.0° |
Mmiri (KF) | ≤0.50% |
Sulfated Ash | ≤0.10% |
Ọla dị arọ | ≤0.002% |
Entiomer | ≤0.30% |
Otu Max.adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ezetimibe (CAS: 163222-33-1) API |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Ezetimibe (CAS: 163222-33-1) bụ ihe mgbochi mbufe cholesterol nke na-ejikọta NPC1L1, bụ nke otu ihe eji eme ka ọkwa cholesterol dị ala n'ọbara bụ ọgwụ na-ebelata ọkwa cholesterol plasma.Ọ na-eme site na ibelata nnabata cholesterol n'ime obere eriri afọ.Enwere ike iji ya naanị mgbe anabataghị ọgwụ ndị ọzọ na-ebelata cholesterol, ma ọ bụ yana statins (dịka ezetimibe/simvastatin) mgbe naanị statins anaghị achịkwa cholesterol.A na-enye Ezetimibe ọnụ naanị ya ma ọ bụ dị ka mbadamba ihe ngwakọta na simvastatin ma ọ bụ atorvastatin.FDA kwadoro Ezetimibe na 2002, n'okpuru aha ahia Zetia.A kwadoro ya maka ojiji na EU dị ka Ezetrol na aha azụmaahịa ndị ọzọ.A na-emepụta ya site na usoro kemịkalụ ọtụtụ nzọụkwụ.