Fingolimod Hydrochloride CAS 162359-56-0 Ịdị Ọcha ≥99.0% (HPLC) API Ụlọ Ọrụ Dị Ọcha Dị Elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha kemịkal: Fingolimod Hydrochloride
OZI: 162359-56-0
Fingolimod Hydrochloride bụ ọgwụ FDA kwadoro maka ọgwụgwọ ọtụtụ Sclerosis.
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Fingolimod Hydrochloride |
Ụdị okwu | Fingolimod HCl;FTY 720 |
Nọmba CAS | 162359-56-0 |
Nọmba CAT | RF-API39 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
Usoro ihe omimi | C19H34ClNO2 |
Ibu molekụla | 343.93 |
Ebe Na-agbaze | 102.0 ~ 107.0°C |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
njirimara | HPLC |
Ebe Na-agbaze | 102.0 ~ 106.0 ℃ |
Solubility | Na-agbaze kpamkpam n'ime mmiri |
Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) |
Mmiri (KF) | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Ihe mgbaze fọdụrụnụ | |
Dichloromethane | ≤0.05% |
Ethyl acetate | ≤0.50% |
Ethanol | ≤0.50% |
Methanol | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Ihe ndị ikwu | |
Otu adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Fingolimod Hydrochloride (CAS: 162359-56-0) nwere àgwà dị elu.
Fingolimod Hydrochloride bụ ọgwụ ọnụ nke mbụ maka ọgwụgwọ ọtụtụ sclerosis.Ụlọ ọrụ na-emepụta ọgwụ Novartis na-emepụta ya nke ọma, ma kwadoro ya maka ịzụ ahịa site na US Food and Drug Administration (FDA).Otutu sclerosis bụ ọrịa akwara na-akụda mmụọ nke nwere ike ime ka onye ọrịa ahụ kwụsị inwe mmetụta nke nguzozi, na-egosi spasms akwara na nsogbu mmegharị ahụ ndị ọzọ.Fingolimod Hydrochloride bụ sphingosine-l-phosphate (S1PR) modulator nnabata.Mgbe phosphorylation gasịrị, Ọ na-ejikọta ya na s1P onye na-anabata ya nke dị n'elu lymphocyte, nke ga-agbanwe mbịgharị lymphocyte, ma kwalite mkpụrụ ndụ n'ime anụ ahụ lymphatic, ma gbochie lymphocytes ịhapụ anụ ahụ lymphoid wee banye n'ime aka.N'ihi ya, ọ ga-egbochi mkpụrụ ndụ ndị a ịbanye n'ime usoro nhụjuanya nke etiti (CNS), nke na-enweta mmetụta nke immunosuppression.