Fondaparinux Sodium CAS 114870-03-0 API

Nkọwa dị mkpirikpi:

Aha Chemical: Fondaparinux Sodium

Ọnọdụ: 114870-03-0

Ọdịdị: White ka Gbanyụọ-Ọcha ntụ ntụ

Nyocha: 95.0% ~ 103.0% (na akpọnwụwo)

Antithrombotic Anticoagulant, ihe na-egbochi Xa

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Nye ya na ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Fondaparinux Sodium
Ọnọdụ: 114870-03-0
Antithrombotic Anticoagulant, ihe na-egbochi Xa
API Ogo dị elu, mmepụta azụmahịa

Njirimara kemịkalụ:

Aha Chemical	Fondaparinux sodium
Nọmba CAS	114870-03-0
Nọmba CAT	RF-API84
Ọnọdụ Ahịa	Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi	C31H43N3O49S8.10Na
Ibu molekụla	1728.08
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ọcha ka Gbanyụọ-Ọcha ntụ ntụ
Usoro nyocha / nyocha	95.0% ~ 103.0% (na a mịrị amị ndabere)
Solubility	Soluble na mmiri n'efu, 2.0M Sodium Chloride na 0.5M Sodium Hydroxide na Apụghị Apụ na Ethanol
njirimara 13C-NMR	Ekwesịrị ịhụ resonances maka Fondaparinux Sodium na 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7mpp na 176.7mpp.Mgbanwe kemịkalụ nke akara ndị a adịghị iche karịa ± 0.3ppm akara ndị ọzọ nke ịdị elu dị elu na mgbanwe kemịkalụ, nke sitere na Fondaparinux Sodium, enwere ike ịhụ n'etiti 58.0 ~ 80.5 ppm na 98.7 ~ 104.5ppm.
njirimara HPLC	Oge njide nke nnukwu ọnụ ọgụgụ kachasị elu nke ngwọta nlele dabara na nke ọkọlọtọ ọkọlọtọ
njirimara AAS	Sodium kwesịrị ịnwe nnabata njirimara na 330.2nm n'okpuru mkpebi nke sodium
pH	6.0-8.0
Sodium (Na)	11.5% ~ 15.0% (gbakọọ na anhydrous na ihe mgbaze n'efu)
Sulfate efu	≤0.30%
Chloride fọdụrụnụ	≤1.00%
Ihe ndị emetụtara
adịghị ọcha A	≤0.80%
adịghị ọcha B	≤0.60%
Ịdịghị Ọcha Ndị Ọzọ	≤0.30%
Mgbakọta adịghị ọcha	≤2.00%
Ihe mgbaze fọdụrụnụ
Methanol	≤3000ppm
Ethanol	≤5000ppm
Ethyl acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤50ppm
Ọdịnaya Mmiri (KF)	≤15.0%
Endotoxins nke nje bacteria	≤3.3EU/mg
Oke Microbial	Ngụkọta ọnụ ọgụgụ microorganisms ≤100cfu/g
Nlele ọkọlọtọ	Ụkpụrụ ụlọ ọrụ;Ọkọlọtọ United States Pharmacopoeia (USP).
Ojiji	API, Antithrombotic Anticoagulant, ihe na-egbochi Xa

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

Fondaparinux Sodium (CAS 114870-03-0) bụ nke mbụ n'ime klas ọhụrụ nke antithrombotic anticoagulant kemịkalụ metụtara heparins dị obere arọ (LMWH).Fondaparinux sodium bụ ihe na-egbochi Xa inhibitor na-etolite saịtị njikọ njikọ dị elu maka ihe mgbochi coagulant antithrombin III (ATIII).Njikọ Fondaparinux sodium na saịtị a na-eme ka mmetụta mgbochi eke sitere na ATIII megide Factor Xa site na ihe dịka 300, nke na-ebute mgbochi nke ọgbọ thrombin.GlaxoSmithKline na-ere ya.A na-ere ụdị ụdị nke Alchemia mepụtara n'ime US site n'aka Dr. Reddy's Laboratories.Ebu ụzọ webatara Fondaparinux sodium na US maka mgbochi nke thrombosis miri emi nke nwere ike ibute mgbakasị akpa ume na-eso nnukwu ịwa ahụ ọkpụkpụ.Ngwakọta molecule sịntetị a kpamkpam bụ nnomi nke usoro heparin pentasaccharide, nke kachasị mkpụmkpụ nwere ike ime ka mgbochi antithrombin llmmediated nke Factor Xa si otú a na-egbochi ọgbọ thrombin na-enweghị ọrụ antithrombin.