Ganciclovir CAS 82410-32-0 API BW 759 GCV mgbochi nje CMV Inhibitor dị elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Ganciclovir
Nọmba: 82410-32-0
Onye nnọchi anya Antiviral maka ọgwụgwọ nke ọrịa cytomegalovirus (CMV).
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Ganciclovir |
Ụdị okwu | GCV;BW 759;9-[[2-Hydroxy-1- (hydroxymethyl)ethoxy]methyl]guanine;2-Amino-9- (1,3-dihydroxypropan-2-yloxymethyl) -3H-purin-6-otu;2'-Nọ-2'-Deoxyguanosine |
Nọmba CAS | 82410-32-0 |
Nọmba CAT | RF-API82 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C9H13N5O4 |
Ibu molekụla | 255.23 |
Ebe Na-agbaze | 250 ℃ |
Okpomọkụ nchekwa | 2-8 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
Solubility | Na-agbaze nke ukwuu na mmiri |
njirimara | Ntinye nke ultraviolet, mmịpụta infrared |
Ọnwụ na ihicha | ≤6.0% |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Ihe ndị emetụtara | Ngwakọta metụtara Ganciclovir A ≤0.50% |
Oke nke guanine | ≤0.50% |
Ihe mgbaze fọdụrụnụ (GC) | Ethanol ≤5000ppm |
Ọla dị arọ | ≤10ppm |
Ọnụọgụ absorption | 516-548 na 252nm |
Endotoxins nke nje bacteria | ≤0.84EU/mg |
Nyocha | 98.0% ~ 102.0% (Titration) |
Nlele ọkọlọtọ | Ụkpụrụ ụlọ ọrụ;Ọkọlọtọ United States Pharmacopoeia (USP). |
Ojiji | API, CMV Inhibitor |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
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Ganciclovir (CAS 82410-32-0) bụ nke ọgwụ antiviral nucleoside, ịbụ ụdị nke guanosine.Ganciclovir bụ onye na - arụ ọrụ na - arụ ọrụ na - arụ ọrụ nke nne na - egosi maka ọrịa cytomegalovirus (CMV) na-eyi ndụ egwu na ndị ọrịa na-adịghị ahụkebe.Ọ nwere nnukwu ụdịdị dị iche iche, mmetụta mgbochi dị elu nke na-egbochi nje herpes na ọ bụ ọgwụ nhọrọ mbụ maka ọgwụgwọ ọrịa cytomegalovirus nwere mmetụta siri ike na nje ịba ọcha n'anya B na adenovirus.Ọ bụ homologue nke acyclovir (ACV) na mmetụta antiviral ya dị ka, mana siri ike karịa aciclovir, na-enwe mmetụta mgbochi siri ike na cytomegalovirus metụtara ndị ọrịa AIDS.A na-eji ya maka ọgwụgwọ nke oge induction na nhazi oge maka ndị ọrịa immunocompromised (gụnyere ndị ọrịa AIDS) nwere retinitis cytomegalovirus n'otu oge.A pụkwara iji ya mee ihe maka igbochi ọrịa cytomegalovirus maka ndị ọrịa na-anata ntụgharị akụkụ ahụ ma ọ bụ ndị ọrịa AIDS nwere nsonaazụ dị mma na cytomegalovirus serology test.
Ganciclovir (CAS 82410-32-0) bụ ihe na-arụ ọrụ nke ọma, nke na-adịghị egbu egbu na onye na-emechi nje virus nke Syntex Company (United States) mepụtara.Ọ bụ ọgwụ mbụ nke US FDA kwadoro maka ọgwụgwọ ọrịa cytomegalovirus (CMV).Enyerela Syntex ikike imepụta ihe.Na June 1988, mbadamba nkume a ka akwadoro na nke mbụ ka edepụta ya na UK, na-esote France, United States, Japan, na West Germany, Italy na Canada na mba ndị ọzọ kwadoro ya.Ruo na njedebe nke June 1999, a kwadoro ya na mba na mpaghara 70 maka igbochi ndị ọrịa na-adịghị ahụkebe na ọrịa cytomegalovirus nke ndị ọrịa na-atụgharị akụkụ ahụ.Na 2002, mbadamba Ganciclovir enwetawo nkwado nke FDA, na-adị ugbu a.
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