Glimepiride CAS 93479-97-1 Assay 98.0%~102.0% API Ụlọ ọrụ dị elu na-adị ọcha egosipụtara

Glimepiride CAS 93479-97-1 Assay 98.0%~102.0% API Ụlọ ọrụ dị ọcha

Nkọwa dị mkpirikpi:

Aha ọgwụ: Glimepiride

Nọmba: 93479-97-1

Ọdịdị: White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ

Nyocha: 98.0% ~ 102.0%

Glimepiride na ọgwụgwọ nke ụdị ọrịa shuga mellitus nke 2 na-adabereghị na Noninsulin

API Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Nye ya na ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha ọgwụ: Glimepiride
Nọmba: 93479-97-1
Glimepiride na ọgwụgwọ nke ụdị ọrịa shuga mellitus nke 2 na-adabereghị na Noninsulin
API Ogo dị elu, mmepụta azụmahịa

Njirimara kemịkalụ:

Aha Chemical	Glimepiride
Ụdị okwu	Amaryl
Nọmba CAS	93479-97-1
Nọmba CAT	RF-API24
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C24H34N4O5S
Ibu molekụla	490.62
Ebe Na-agbaze	212.2-214.5 ℃
Ọnọdụ mbupu	N'okpuru ọnọdụ okpomọkụ
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ntụ ntụ ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ọcha
njirimara	IR (yiri na ọkọlọtọ)
Ihe ndị emetụtara
Cis-Isomer (A)	≤0.80%
Sulfonamide (B)	≤0.40%
Uretane (C)	≤0.10%
3-Isomer (D)	≤0.20%
Ọdịghị ọcha ọ bụla ọzọ	≤0.10%
Mgbakọta adịghị ọcha	≤0.50%
Ọnwụ na ihicha	≤0.50%
Ihe fọdụrụ na mgbanye	≤0.10%
Ọla dị arọ	≤0.001%
Nyocha	98.0% ~ 102.0%
Nlele ọkọlọtọ	European Pharmacopeia (EP);United States Pharmacopoeia (USP)
Ojiji	Ngwakọta ọgwụ na-arụ ọrụ (API)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Glimepiride (CAS: 93479-97-1) nwere àgwà dị elu, ọgwụ na-arụ ọrụ ọgwụ (API).Glimepiride bụ ọgwụ antidiabetic nke na-enyere aka ịchịkwa ọkwa shuga dị n'ọbara.Glimepiride bụ sulfonylurea ọgbọ nke atọ na-arụ ọrụ ogologo oge yana ọrụ hypoglycemic.

Glimepiride (aha ahia izizi Amaryl) bụ ọgwụ antidiabetic sulfonylurea na-adịru ogologo ruo ogologo oge.Dị ka sulfonylureas niile, glimepiride na-arụ ọrụ dị ka ihe nzuzo insulin.Ọ na-ebelata shuga ọbara site na ịkpali ntọhapụ nke insulin site na mkpụrụ ndụ beta nke pancreatic na-arụ ọrụ yana site n'ịbawanye mmetụta nke anụ ahụ dị n'akụkụ na insulin.Glimepiride nwere ike jikọta na ndị na-anabata ọwa potassium nwere mmetụta ATP n'elu sel pancreatic, na-ebelata njikwa potassium na-eme ka akpụkpọ ahụ ghara ịdị.Depolarization nke membrane na-akpali mbata calcium ion site na ọwa calcium nwere mmetụta voltaji.Mmụba a na ntinye uche nke calcium ion intracellular na-akpali mmepụta insulin.A na-ejikarị Glimepiride agwọ ndị ọrịa nwere ụdị ọrịa shuga 2 ma nwee ike ibelata ohere mmadụ nwere ike ịmalite nsogbu nke ụdị ọrịa shuga 2.FDA kwadoro ọgwụ a na 1995 ma Sanofi-Aventis rụpụtara ya.Enwere ike iji ya yana nri kwesịrị ekwesị na mmemme mmega ahụ, enwere ike iji ya naanị ya ma ọ bụ ọgwụ antidiabetic ndị ọzọ ma ọ dị mkpa.Enwere ike iji Glimepiride mee ihe dị ka monotherapy ma ọ bụ yana yana insulin.