Guanfacine Hydrochloride Guanfacine HCl CAS 29110-48-3 API USP Ọkọlọdị Ọcha Dị Elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha kemịkal: Guanfacine Hydrochloride
Nkọwa okwu: Guanfacine HCl
Ọkụ: 29110-48-3
Guanfacine Hydrochloride bụ agonist α2A-adrenoceptor nhọrọ.Antihypertensive
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Guanfacine Hydrochloride |
Ụdị okwu | Guanfacine HCl |
Nọmba CAS | 29110-48-3 |
Nọmba CAT | RF-API40 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C9H10Cl3N3O |
Ibu molekụla | 282.55 |
Ebe Na-agbaze | 211.0 ~ 215.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
njirimara | Infrared absorption;HPLC |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Ọla dị arọ | ≤20ppm |
Nyocha | 98.0% ~ 102.0% (HPLC na ntọala a mịrị amị) |
Chromatographic ịdị ọcha | ≥99.0% |
Nlele ọkọlọtọ | USP Standard |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
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Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Guanfacine Hydrochloride (CAS: 29110-48-3) nwere àgwà dị elu.
Guanfacine hydrochloride na-eme ihe n'etiti agonist a-adrenoceptor.Antihypertensive.Guanfacine hydrochloride, onye na-egbochi ọbara mgbali elu, bụ agonist α2A-adrenoceptor nke nwere Kd nke 31 nM wee gosipụta 60-fold selectivity n'elu α2B-adrenoceptors.Guanfacine na-ebelata ma systolic na ọbara mgbali elu diastolic site na ịgbalite sistemu ụjọ nke etiti α2A norepinephrine autoreceptors, nke na-ebute mbelata mmetụta ọmịiko na-apụ apụ ma si otú a na-ebelata ụda ọmịiko.Ngwa ọgwụgwọ maka guanfacine yiri nke ndị ọzọ na-eme α2-adrenergic agonists na methyldopa.Ọ dị irè dị ka monotherapy na ọgwụgwọ nke ndị ọrịa nwere ọbara mgbali elu dị nwayọọ ma na-agafeghị oke.
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