Histrelin Acetate CAS 76712-82-8 Peptide Purity (HPLC) ≥98.0% Ụlọ ọrụ
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na-emepụta Histrelin Acetate (CAS: 76712-82-8) na elu mma.Ruifu Chemical na-enye usoro peptides GMP.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta Histrelin Acetate,Please contact: alvin@ruifuchem.com
Aha Chemical | Histrelin acetate |
Ụdị okwu | Histrelin;Histrelin acetic acid nnu;Aha ika Supprelin (Roberts Pharmaceutical);[des-Gly 10, D-His (Bzl) 6] -LH-RH Ethylamide;5-oxo-L-Prolyl-L-Histidyl-L-Tryptophyl-Lseryl-L-Tyrosyl-Nt-Benzyl-D-Histidyl-L-Leucyl-L-Arginyl-N-Ethyl-L-Prolinamide Diacetate |
Usoro Peptide | Pyr-His-Trp-Ser-Tyr-D-His (Bzl) -Leu-Arg-Pro-NHEt Acetate Nnu |
Ụdị nnu | Acetate |
Ọnọdụ Ahịa | N'ọkwa, Azụmahịa Azụmahịa |
Nọmba CAS | 76712-82-8 |
Usoro ihe omimi | C66H86N18O12 |
Ibu molekụla | 1323.52 g/mol |
Njupụta | 1.46±0.10 g/cm3 |
Mmetụta | Hygroscopic.Mmiri nwere mmetụta |
Okpomọkụ nchekwa. | Ebe dị jụụ na nkụ (2 ~ 8 ℃).Igwe nju oyi |
COA & MSDS | Dị |
Otu | GMP Peptides |
Ndụ shelf | Ọnwa 24 Site na ụbọchị nrụpụta ma ọ bụrụ na echekwara ya nke ọma |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | Ọcha Lyophilized ntụ ntụ | Dabara |
Solubility | Soluble na mmiri ma ọ bụ 1% acetic acid na ntinye nke ≥1mg/ml iji nye ngwọta enweghị agba doro anya. | Dabara |
MS | Monoisotopic Mass: 1323±1.0 | 1323.1 |
Njirimara HPLC | Otu ihe na Ngwọta ntụaka | Dabara |
Amino acid Analysis | Ser: Ugbu a | Dabara |
Glu: 0.85 ~ 1.1 | 0.95 | |
Pro: 0.85 ~ 1.1 | 1.05 | |
Leu: 0.85 ~ 1.1 | 1.01 | |
Ọrụ: 0.85 ~ 1.1 | 1.00 | |
Aha ya: 1.70 ~ 2.2 | 0.99 | |
Agba: 0.85 ~ 1.1 | 0.98 | |
Trp: Ugbu a | Kpebisiri ike | |
Peptide dị ọcha (HPLC) | ≥98.0% | 99.58% |
Ihe ndị emetụtara (HPLC) | Mkpokọta adịghị ọcha(%) ≤2.0% | 0.42% |
Ọdịghị ọcha ọ bụla ọzọ ≤1.0% | 0.24% | |
Ọdịnaya Acetate (HPLC) | ≤12.0% | 11.5% |
Ọdịnaya Mmiri (Karl Fischer) | ≤5.0% | 1.0% |
Nyocha | 95.0 ~ 105.0% (Anhydrous, Acetic Acid efu) | 98.5% |
Mmalite nke ngwaahịa | sịntetik | |
Nlebara anya | Naanị maka nyocha, ọ bụghị maka ojiji mmadụ | |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwapụta |
ngwugwu:Plastic vial (raara onwe ya nye maka mbukota peptide) ma ọ bụ vial iko, ọnụọgụ dị ka nkọwa ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mkpuchi mkpuchi n'ụlọ nkwakọba ihe dị jụụ na nkụ (2 ~ 8 ℃) pụọ na ihe ndị na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Nyefee n'ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Akara egwu T - Nsi
Koodu ihe egwu
60 - Nwere ike imebi ọmụmụ
Nkọwapụta nchekwa
S53 - Zere ikpughe - nweta ntuziaka pụrụ iche tupu ejiri ya.
S22 - Ekula uzuzu.
S36/37/39 - Yiri uwe nchebe kwesịrị ekwesị, uwe aka na nchebe anya / ihu.
S45 - Ọ bụrụ na ihe mberede ma ọ bụ ọ bụrụ na ahụ adịghị gị mma, chọọ ndụmọdụ ahụike ozugbo (gosi akara ahụ mgbe ọ bụla enwere ike.)
WGK Germany 3
RTECS OK6370800
Histrelin Acetate (CAS: 76712-82-8), agonist nke gonadotrophin na-ewepụta hormone (GnRH), ka ewepụtara dị ka usoro ọgwụgwọ mbụ maka ọgwụgwọ nke etiti oge ntozu oke.Mgbe a na-enye ya ogologo oge, ọ na-egbochi mwepụta nke gonadotrophin, na-egbochi ovarian na testicular steroidogenesis, ma na-egbochi ntozu okè mmekọahụ.Karịrị usoro ọgwụgwọ ọdịnala na ndị nnọchi anya progestational, histrelin na-egosi na ọ na-enwe mmetụta na-agbadata n'ọkpụkpụ skeletal maturation na-enye ohere ka uto statural na-abawanye nke ukwuu na ogo okenye ikpeazụ.A na-ejikwa Histrelin na-agwọ ọrịa ndị ọzọ gụnyere endometriosis, ọrịa polycystic ovary, uterine leiomyomas, ọrịa premenstrual siri ike na igbochi nnukwu ọrịa porphyria.
Nkọwa: Oligopeptide nke nwere pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, na N-ethylprolinamide residues jikọtara n'usoro.Ọ bụ ihe analog nke nonapeptide sịntetik nke gonadotro na-ewepụta homonụ, a na-ejikwa ya dị ka ntinye hydrogel subcutaneous (karịsịa dị ka nnu diacetate) maka ọgwụgwọ ọrịa kansa prostate yana maka mbelata mmepụta homonụ mmekọahụ gonadal na ụmụaka nwere oge ntozu oke.Ejiri ya maka oge ntozu oke.
Omume biochem / Physiol: Histrelin Acetate bụ GnRH (hormone na-ahapụ gonadotropin) agonist, histerelin.GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), nke a na-akpọkwa LHRH (hormone na-ahapụ hormone luteinizing) ma ọ bụ gonadorelin, dị oké mkpa maka ịmụ nwa ma na-ahapụ ya na ya. neurons hypothalamic.Ọ na-ahụ maka mmepụta nke gonadotropins, hormone luteinizing (LH) na hormone na-akpali akpali (FSH), site na gland pituitary.Mmụba na GnRH na-ejikọta normosmic congenital hypogonadotropic hypogonadism.A na-eji Histerelin maka ọgwụgwọ nke etiti oge ntozu ụmụaka.Ọ na-egbochi omume nke steroid mmekọahụ na akụkụ ọmụmụ nwoke na nwanyị.
Ọ dị ka ịgba ọgwụ intramuscular kwa ụbọchị.Histrelin dịkwa na ntinye nke ọnwa iri na abụọ (Vantas) maka ọgwụgwọ palliative nke ọrịa cancer prostate dị elu (ebe 2005 na US, na kemgbe Jan 2010 na UK. A 12 ọnwa subcutaneous implant (Supprelin LA) maka Central precocious. ikike ntozu (CPP) ka ndị nchịkwa nri na ọgwụ US kwadoro na Mee 3, 2007.