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N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Cleanity Featured Image
  • N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Nkọwa dị mkpirikpi:

N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine

Nọmba: 152460-09-8

Ọdịdị: Yellow ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ

Ịdị ọcha: ≥98.0% (HPLC)

Otiti nke Imatinib Mesylate (CAS: 220127-57-1) na ọgwụgwọ nke Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Mbubata Azụmahịa Imatinib Mesylate na ihe ndị metụtara ya:
Imatinib Mesylate CAS: 220127-57-1
N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine CAS: 152460-09-8
N- (5-Amino-2-methylphenyl) -4- (3-pyridyl) -2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl) methyl] benzoic acid dihydrochloride CAS: 106261-49-8

Njirimara kemịkalụ:

Aha Chemical N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine
Ụdị okwu Imatinib Mesylate Intermediate;2- (2-Methyl-5-nitroanilino) -4- (3-pyridyl) pyrimidine.
Nọmba CAS 152460-09-8
Nọmba CAT RF-PI228
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C16H13N5O2
Ibu molekụla 307.31
Ebe Na-agbaze 188.0-193.0 ℃
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Yellow ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ
Ịdị ọcha ≥98.0% (HPLC)
Mmiri (KF) ≤0.50%
Mgbakọta adịghị ọcha ≤2.0%
Oke adịghị ọcha otu ≤1.0%
Ihe fọdụrụ na mgbanye ≤0.50%
Ọla dị arọ ≤20ppm
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ọkara nke Imatinib Mesylate (CAS: 220127-57-1)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.

Uru:

1

Ajụjụ:

Ngwa:

Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata N (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) na elu mma.Ọ bụ etiti na-emekarị na njikọ nke Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate bụ obere molekul nke na-egbochi c-Abl protein-tyrosine kinase, nke ukwuu maka BCR-ABL, enzyme jikọtara ya na ọrịa leukemia myelogenous na-adịghị ala ala (CML) na ụdị ụfọdụ nke nnukwu ọrịa leukemia lymphoblastic (ALL).Ihe omume ntụgharị n'etiti chromosomes 9 na 22 na-emepụta chromosome Philadelphia, nke na-emepụta protein Bcr-Able fusion na ọrụ kinase aberrant nke na-akwalite mgbasawanye cell ngwa ngwa.Imatinib Mesylate na-ejikọta kinase a dị mkpa, na-akwụsị uto metụtara CML.Imatinib Mesylate ka egosiputala iji gbochie PDGFR na tyrosine kinases metụtara c-Kit.A na-eji usoro ndị nwere Imatinib Mesylate eme ihe n'ịgwọ ọrịa cancer dị iche iche.

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