N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity
Mbubata Azụmahịa Imatinib Mesylate na ihe ndị metụtara ya:
Imatinib Mesylate CAS: 220127-57-1
N- (2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl) pyrimidin-2-amine CAS: 152460-09-8
N- (5-Amino-2-methylphenyl) -4- (3-pyridyl) -2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl) methyl] benzoic acid dihydrochloride CAS: 106261-49-8
Aha Chemical | N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine |
Ụdị okwu | Imatinib Mesylate Intermediate;2- (2-Methyl-5-nitroanilino) -4- (3-pyridyl) pyrimidine. |
Nọmba CAS | 152460-09-8 |
Nọmba CAT | RF-PI228 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C16H13N5O2 |
Ibu molekụla | 307.31 |
Ebe Na-agbaze | 188.0-193.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Yellow ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ |
Ịdị ọcha | ≥98.0% (HPLC) |
Mmiri (KF) | ≤0.50% |
Mgbakọta adịghị ọcha | ≤2.0% |
Oke adịghị ọcha otu | ≤1.0% |
Ihe fọdụrụ na mgbanye | ≤0.50% |
Ọla dị arọ | ≤20ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Imatinib Mesylate (CAS: 220127-57-1) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.
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Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata N (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) na elu mma.Ọ bụ etiti na-emekarị na njikọ nke Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate bụ obere molekul nke na-egbochi c-Abl protein-tyrosine kinase, nke ukwuu maka BCR-ABL, enzyme jikọtara ya na ọrịa leukemia myelogenous na-adịghị ala ala (CML) na ụdị ụfọdụ nke nnukwu ọrịa leukemia lymphoblastic (ALL).Ihe omume ntụgharị n'etiti chromosomes 9 na 22 na-emepụta chromosome Philadelphia, nke na-emepụta protein Bcr-Able fusion na ọrụ kinase aberrant nke na-akwalite mgbasawanye cell ngwa ngwa.Imatinib Mesylate na-ejikọta kinase a dị mkpa, na-akwụsị uto metụtara CML.Imatinib Mesylate ka egosiputala iji gbochie PDGFR na tyrosine kinases metụtara c-Kit.A na-eji usoro ndị nwere Imatinib Mesylate eme ihe n'ịgwọ ọrịa cancer dị iche iche.