Inosine CAS 58-63-9 Assay 98.0 ~ 102.0% Ụlọ ọrụ dị elu
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Inosine (CAS: 58-63-9) nwere àgwà dị elu, na-ezute ọkọlọtọ Chinese Pharmacopoeia ChP2020 II.A na-eresị ngwaahịa anyị na America na Europe, India, yana ụlọ ọrụ ọgwụ ama ama na China.Ngwaahịa ahụ enwetala aha dị elu n'ahịa mba ụwa na nke ụlọ.Anyị nwere ike ịnye nnyefe zuru ụwa ọnụ, obere na nnukwu ọnụọgụ dị.Ọ bụrụ na ị nwere mmasị na Inosine (CAS: 58-63-9),Please contact: alvin@ruifuchem.com
Aha Chemical | Inosine |
Ụdị okwu | (-) Inosine;Hypoxanthine 9-β-D-Ribofuranoside;Hypoxanthine-9-beta-D-Ribofuranoside;Atorel;beta-inosine;Hypoxanthine D-Riboside;1,9-Dihydro-9-β-D-Ribofuranosyl-6H-purin-6-otu;Hypoxanthine riboside;Hypoxanthine ribonucleoside;9-β-D-Ribofuranosylhypoxanthine |
Ọnọdụ Ahịa | N'ahịa, Ikike Mmepụta Tọn 30 kwa ọnwa |
Nọmba CAS | 58-63-9 |
Usoro ihe omimi | C10H12N4O5 |
Ibu molekụla | 268.23 |
Ebe Na-agbaze | 222.0 ~ 226.0 ℃ (dec.) (ọkụ) |
Mmetụta | Hygroscopic |
Solubility | Na-agbaze ntakịrị n'ime mmiri, Apụghị Soluble na Ethanol, yana Soluble na Dilute Hydrochloric Acid na Sodium Hydroxide Solution. |
Isi | Enweghị isi |
Okpomọkụ nchekwa. | Edechiri ya na nkụ, na-echekwa na okpomọkụ ụlọ |
COA & MSDS | Dị |
Ụdị | Ruifu Chemical |
Koodu egwu | Xi - mgbakasị ahụ | RTECS | NM7460000 |
Nkwupụta ihe egwu | 36/37/38 | F | 10 |
Nkwupụta nchekwa | 24/25-36-26 | TSCA | Ee |
WGK Germany | 2 | Koodu HS | 2934993090 |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | kristal ọcha ma ọ bụ ntụ ntụ kristal;Enweghị isi;Ụtụ ilu | Dabara |
njirimara | 1) Gosi mmeghachi omume dị mma 2) Oge njide kwekọrọ na ọkọlọtọ 3) nnabata infrared | Dabara |
Ọnọdụ Ngwọta (Nfefe) | ≥98.0% | Dabara |
Ọla dị arọ (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0pm | <1.0pm |
Ọnwụ na ihicha | ≤1.00% (na 105℃ maka awa 3) | 0.40% |
Ihe fọdụrụ na mgbanye (Sulfated) | ≤0.20% | 0.07% |
Ihe ndị emetụtara | Ngụkọta elu elu nke adịghị ọcha karịrị 1.0% nke mpaghara peek izugbe | Dabara |
Nyocha | 98.0 ruo 102.0% | 99.4% |
Uru pH | 4.8 ruo 5.8 (1.0g na 100ml nke H2O) | 5.0 |
Nnwale Microbiological | ||
Mkpokọta oke ikuku | ≤800CFU/g | 40CFU/g |
Mkpokọta oke oke | ≤80 CFU/g | 10CFU/g |
Yist | ≤80 CFU/g | 10CFU/g |
Escherichia Coli | Ihe ọjọọ | Ihe ọjọọ |
Mmechi | Zutere ọkọlọtọ nke ChP2020 II |
Inosine (CAS: 58-63-9) Usoro nnwale ChP2020
Inosine - nkọwa
Ọdịnaya nke C10H12N4O5 ga-adị n'etiti 98.0% na 102.0% gbakọọ na ngwaahịa akpọnwụwo.
Inosine - Àgwà ngwaahịa a bụ ọcha crystalline ntụ ntụ;Enweghị isi.Ngwaahịa a na-agbaze ntakịrị n'ime mmiri, nke na-esighi ike na ethanol, yana soluble na ngwọta hydrochloric acid na sodium hydroxide ngwọta.
Inosine - IHE
1. Were ego kwesịrị ekwesị nke 0.01% ngwọta nke ngwaahịa a, tinye nha nha nha nke 3, 5-dihydroxytoluene ngwọta (were 3, 5-dihydroxytoluene na ferric chloride 0.lg, tinye hydrochloric acid iji mee 100ml), jikọta nke ọma, mgbe e mesịrị. kpo oku n'ime mmiri ịsa mmiri maka ihe dịka nkeji 10, a hụrụ agba ndụ ndụ.
2. N'ime chromatogram nke edere n'okpuru ihe nrịbama nke ọdịnaya, oge njigide nke isi ihe kachasị elu nke ngwọta ule kwesịrị ịdị na-adabere na oge njigide nke isi ihe ntinye aka.
3. Ụdị nnabata infrared nke ngwaahịa a kwesịrị ịdị na nke njikwa (Spectrum set 605).
Inosine - nyocha
Mbufe nke Ngwọta
Were 0.5g nke ngwaahịa a, tinye 50ml mmiri ka igbari, dị ka UV-visible spectrophotometry (General rule 0401), chọpụta nnyefe na 430nm wavelength, ọ bụghị ihe na-erughị 98.0%.(Maka injection)
Ihe ndị emetụtara
Were ngwaahịa a, gbakwunye mmiri ka ọ gbazee na itughari iji mee ihe ngwọta nwere 0.5mg kwa 1ml dị ka ngwọta ule;Were 1ml maka nha nkenke, tinye ya n'ime iko 100ml, gbanye ya na mmiri na nha nha, dịka ngwọta nchịkwa.Dị ka ọnọdụ chromatographic dị n'okpuru ihe mkpebi nke ọdịnaya, 20 u1 nke ngwọta ule na ngwọta nchịkwa na-agbanye n'otu n'otu n'ime chromatograph mmiri mmiri, na chromatogram na-edekọ ugboro abụọ nke oge njide nke isi elu.Ọ bụrụ na enwere ọnụ ọgụgụ adịghị ọcha na chromatogram nke ngwọta ule, nchikota nke mpaghara ọ bụla adịghị ọcha agaghị adị karịa ebe kachasị elu nke ngwọta nchịkwa (1.0%).
Ọnwụ na ihicha
Were ngwaahịa a, kpọọ nkụ ka ọ dị arọ mgbe niile na 105 ° C, oke ibu agaghị agafe 1.0% (Iwu n'ozuzu 0831).
Ihe fọdụrụ na mgbanye (Sulfated)
Ọ bụghị karịa 0.1% (maka ntụtụ), ma ọ bụ karịa 0.2% (maka ọnụ ọnụ) (Iwu n'ozuzu 0841).
Ọla dị arọ
Were ngwaahịa a 1.0g, nyocha dịka iwu siri dị (General Principles 0821 second law), nwere ọla dị arọ agaghị agafe akụkụ 10 kwa nde.
Nsi na-adịghị mma
Were ngwaahịa a, gbakwunye injection sodium chloride ka ọ gbazee na itughari ihe ngwọta nwere inosine 10mg kwa 1ml, lelee dịka iwu siri dị (Iwu General 1141), kwesịrị ịgbaso ndokwa.(Maka injection)
Inosine - Mkpebi ọdịnaya
Chromatography Liquid Liquid Arụ Ọrụ Dị Elu (General 0512) tụrụ.
A na-eji ọnọdụ chromatographic na dabara adaba sistemụ silica gel jikọtara ya na alkyl silane iri na asatọ dị ka ihe ndochi;A na-eji methanol-mmiri (10:90) mee ihe dị ka usoro mkpanaka;Ogologo ebili mmiri a chọpụtara bụ 248nm.Were ihe dị ka 10mg nke ntụaka inosine, gbakwunye 1 mol/L hydrochloric acid solution (1ml), kpoo ọkụ na mmiri ịsa ahụ na 80 ℃ maka nkeji 10, hapụ ya ka ọ dị jụụ, tinye 1ml nke 1 mol / L sodium hydroxide solution, tinye mmiri na 50ml, 20u1 injection mmiri chromatograph, mezie sistemu chromatographic, ogo nkewa nke inosine kacha elu na adịghị ọcha dị n'akụkụ kwesịrị izute ihe ndị a chọrọ, ọnụ ọgụgụ nke efere usoro dị ka ngụkọta ọnụ ọgụgụ inosine si erughị 2000.
Nyocha
Were ngwaahịa a kwesịrị ekwesị, tụọ ya nke ọma, gbakwunye mmiri ka ọ gbazee ma mee ka ọ bụrụ ihe ngwọta nwere ihe dị ka 20ug kwa lml, gbanye ya ma jiri ya dị ka ihe nyocha, A 20ul injection liquid chromatograph ziri ezi tụrụ na e dekọrọ chromatogram ahụ.A tụlere ọnụọgụ inosine kwesịrị ekwesị nke ọma site n'otu usoro ahụ, wee gbakọọ mpaghara kachasị elu dịka usoro ọkọlọtọ mpụga siri dị.
Inosine - ngalaba
Ọgwụ na-emeziwanye metabolism cell.
Inosine - Nchekwa
Ihe mkpuchi ọkụ, nchekwa akara.
Ọgwụ: (1) Inosine Oral Ngwọta (2) Inosine Mbadamba ụrọ (3) Inosine Injection (4) Inosine Capsules (5) Inosine na Glucose Injection (6) Inosine na Sodium Chloride Injection (7) Inosine maka ịgba ọgwụ.
ngwugwu: Fluorinated karama, 25kg / akpa, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mechiri emechi n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na ikuku ikuku na-anọghị n'ihe na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
1. Inosine (CAS: 58-63-9), dị ka ngwaahịa nucleoside, a na-ejikarị emepụta ọgwụ maka ọgwụgwọ ọrịa nje na ọrịa ndị ọzọ.
2. Inosine bụ nucleotide na-abụghị nke canonical bụ nke dị ka monophosphate.Ọ nwere ike ijikọ deoxythymidine, deoxyadenosine na deoxyguanosine.Ntinye inosine n'ọnọdụ guanine na-agbanwe mmemme ntụgharị asụsụ.Inosin nwere antioxidant, mgbochi mkpali na ọrụ neuroprotective.A na-enye Inosine ka ọ bụrụ mgbakwunye ọgwụgwọ maka mmerụ ahụ akwara, mbufụt na nrụgide oxidative.Ọ na-agbanwe usoro ndu site na ndị na-anabata adenosine.Ọ na-akwalite uto neurite na nsogbu ịda mbà n'obi site na ndị na-anabata adenosine.A na-ejikwa Inosine agwọ ọrịa sepsis na ọrịa.
3. Inosine bụ ihe dị mkpa nke ahụ mmadụ, ụdị ọgwụ coenzyme nke a na-ejikarị eme ihe na nkà mmụta ọgwụ na ụlọ ọrụ nri.Ọ nwere ike banye n'ime akpụkpọ ahụ cell n'ime cell nke ahụ ozugbo, ma mee ka cell ahụ nọrọ n'ọnọdụ nke enweghị ike na anoxia na-aga n'ihu na-edozi ahụ nke ọma.Ọ nwere ike rụọ ọrụ caetone acid oxides, ma sonye na protein ahụ na nhazi.
Ngwa nke ọgwụ Inosine, dị ka mbadamba inosine na inosine injection.
1. Ejiri ya na ọgwụgwọ leucopenia na thrombocytopenia.
2. Na ọgwụgwọ nke nnukwu ịba ọcha n'anya na-adịghị ala ala ịba ọcha n'anya na imeju cirrhosis, imeju encephalopathy.
3. A na-eji maka ọrịa obi atherosclerotic na-arịa ọrịa obi (ọrịa obi na-efe efe), ọrịa myocardial infarction, ọrịa obi rheumatic, cor pulmonale inyeaka ọgwụ.
4. A na-eji egbochi na ibelata ọgwụ mgbochi schistosomiasis nke obi na nsị imeju kpatara.
5. A na-eji maka ọrịa anya (mbufụt nke etiti etiti, optic atrophy) iji ọgwụ inyeaka.
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