Inosine CAS 58-63-9 Assay 98.0 ~ 102.0% Ụlọ ọrụ dị elu

Inosine (CAS: 58-63-9) Usoro nnwale ChP2020
Inosine - nkọwa
Ọdịnaya nke C10H12N4O5 ga-adị n'etiti 98.0% na 102.0% gbakọọ na ngwaahịa akpọnwụwo.
Inosine - Àgwà ngwaahịa a bụ ọcha crystalline ntụ ntụ;Enweghị isi.Ngwaahịa a na-agbaze ntakịrị n'ime mmiri, nke na-esighi ike na ethanol, yana soluble na ngwọta hydrochloric acid na sodium hydroxide ngwọta.
Inosine - IHE
1. Were ego kwesịrị ekwesị nke 0.01% ngwọta nke ngwaahịa a, tinye nha nha nha nke 3, 5-dihydroxytoluene ngwọta (were 3, 5-dihydroxytoluene na ferric chloride 0.lg, tinye hydrochloric acid iji mee 100ml), jikọta nke ọma, mgbe e mesịrị. kpo oku n'ime mmiri ịsa mmiri maka ihe dịka nkeji 10, a hụrụ agba ndụ ndụ.
2. N'ime chromatogram nke edere n'okpuru ihe nrịbama nke ọdịnaya, oge njigide nke isi ihe kachasị elu nke ngwọta ule kwesịrị ịdị na-adabere na oge njigide nke isi ihe ntinye aka.
3. Ụdị nnabata infrared nke ngwaahịa a kwesịrị ịdị na nke njikwa (Spectrum set 605).
Inosine - nyocha
Mbufe nke Ngwọta
Were 0.5g nke ngwaahịa a, tinye 50ml mmiri ka igbari, dị ka UV-visible spectrophotometry (General rule 0401), chọpụta nnyefe na 430nm wavelength, ọ bụghị ihe na-erughị 98.0%.(Maka injection)
Ihe ndị emetụtara
Were ngwaahịa a, gbakwunye mmiri ka ọ gbazee na itughari iji mee ihe ngwọta nwere 0.5mg kwa 1ml dị ka ngwọta ule;Were 1ml maka nha nkenke, tinye ya n'ime iko 100ml, gbanye ya na mmiri na nha nha, dịka ngwọta nchịkwa.Dị ka ọnọdụ chromatographic dị n'okpuru ihe mkpebi nke ọdịnaya, 20 u1 nke ngwọta ule na ngwọta nchịkwa na-agbanye n'otu n'otu n'ime chromatograph mmiri mmiri, na chromatogram na-edekọ ugboro abụọ nke oge njide nke isi elu.Ọ bụrụ na enwere ọnụ ọgụgụ adịghị ọcha na chromatogram nke ngwọta ule, nchikota nke mpaghara ọ bụla adịghị ọcha agaghị adị karịa ebe kachasị elu nke ngwọta nchịkwa (1.0%).
Ọnwụ na ihicha
Were ngwaahịa a, kpọọ nkụ ka ọ dị arọ mgbe niile na 105 ° C, oke ibu agaghị agafe 1.0% (Iwu n'ozuzu 0831).
Ihe fọdụrụ na mgbanye (Sulfated)
Ọ bụghị karịa 0.1% (maka ntụtụ), ma ọ bụ karịa 0.2% (maka ọnụ ọnụ) (Iwu n'ozuzu 0841).
Ọla dị arọ
Were ngwaahịa a 1.0g, nyocha dịka iwu siri dị (General Principles 0821 second law), nwere ọla dị arọ agaghị agafe akụkụ 10 kwa nde.
Nsi na-adịghị mma
Were ngwaahịa a, gbakwunye injection sodium chloride ka ọ gbazee na itughari ihe ngwọta nwere inosine 10mg kwa 1ml, lelee dịka iwu siri dị (Iwu General 1141), kwesịrị ịgbaso ndokwa.(Maka injection)
Inosine - Mkpebi ọdịnaya
Chromatography Liquid Liquid Arụ Ọrụ Dị Elu (General 0512) tụrụ.
A na-eji ọnọdụ chromatographic na dabara adaba sistemụ silica gel jikọtara ya na alkyl silane iri na asatọ dị ka ihe ndochi;A na-eji methanol-mmiri (10:90) mee ihe dị ka usoro mkpanaka;Ogologo ebili mmiri a chọpụtara bụ 248nm.Were ihe dị ka 10mg nke ntụaka inosine, gbakwunye 1 mol/L hydrochloric acid solution (1ml), kpoo ọkụ na mmiri ịsa ahụ na 80 ℃ maka nkeji 10, hapụ ya ka ọ dị jụụ, tinye 1ml nke 1 mol / L sodium hydroxide solution, tinye mmiri na 50ml, 20u1 injection mmiri chromatograph, mezie sistemu chromatographic, ogo nkewa nke inosine kacha elu na adịghị ọcha dị n'akụkụ kwesịrị izute ihe ndị a chọrọ, ọnụ ọgụgụ nke efere usoro dị ka ngụkọta ọnụ ọgụgụ inosine si erughị 2000.
Nyocha
Were ngwaahịa a kwesịrị ekwesị, tụọ ya nke ọma, gbakwunye mmiri ka ọ gbazee ma mee ka ọ bụrụ ihe ngwọta nwere ihe dị ka 20ug kwa lml, gbanye ya ma jiri ya dị ka ihe nyocha, A 20ul injection liquid chromatograph ziri ezi tụrụ na e dekọrọ chromatogram ahụ.A tụlere ọnụọgụ inosine kwesịrị ekwesị nke ọma site n'otu usoro ahụ, wee gbakọọ mpaghara kachasị elu dịka usoro ọkọlọtọ mpụga siri dị.
Inosine - ngalaba
Ọgwụ na-emeziwanye metabolism cell.
Inosine - Nchekwa
Ihe mkpuchi ọkụ, nchekwa akara.
Ọgwụ: (1) Inosine Oral Ngwọta (2) Inosine Mbadamba ụrọ (3) Inosine Injection (4) Inosine Capsules (5) Inosine na Glucose Injection (6) Inosine na Sodium Chloride Injection (7) Inosine maka ịgba ọgwụ.