Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Dị Ọcha> Ụlọ ọrụ 99.0% (HPLC)
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tritil Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Aha Chemical | 2-Butyl-1,3-diazaspiro[4.4] na-abụghị 1-en-4-otu Hydrochloride |
Ụdị okwu | Irbesartan Side Chain Hydrochloride;Irbesartan Lactam adịghị ọcha;Irbesartan adịghị ọcha A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-otu Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4] na-abụghị 1-en-4-otu HCl |
Nọmba CAS | 151257-01-1 |
Nọmba CAT | RF-PI1894 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C11H18N2O·HCl |
Ibu molekụla | 230.74 |
Solubility na Mmiri | Soluble na Mmiri |
Ebe Na-agbaze | 235.0 ~ 240.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
Ọnwụ na ihicha | <0.50% |
Ihe fọdụrụ na mgbanye | <0.20% |
Mgbakọta adịghị ọcha | <1.00% |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Irbesartan (CAS: 138402-11-6) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
2-Butyl-1,3-diazaspiro[4.4] na-abụghị 1-en-4-otu Hydrochloride (CAS: 151257-01-1), makwaara dị ka Irbesartan Side Chain Hydrochloride, bụ Intermediate nke Irbesartan (Avapro) (CAS). : 138402-11-6).Irbesartan bụ angiotensin II receptor inhibitor, ndị na-anabata angiotensin II na-ekewa n'ime AT1, AT2, irbesartan nwere ike igbochi AngⅠtransform n'ime AngII site na-ahọpụtara igbochi AT1 receptor AngII, kpọmkwem na-emegide angiotensin na-agbanwe enzyme 1 receptor (AT1) nke antagonism. ugboro karịa nke AT2, ọ nwere ike igbochi vasoconstriction na ntọhapụ aldosterone site na ịhọrọ nke ọma igbochi AngII na-ejikọta ya na onye na-anabata AT1 ma mee ka mmetụta antihypertensive pụta.Ngwaahịa a anaghị egbochi angiotensin na-agbanwe enzyme (ACE), renin, na ndị na-anabata homonụ ndị ọzọ, anaghị egbochi usoro ọbara mgbali na nguzozi nke ọwa sodium ion.Irbesartan nwekwara ike ibelata mmezigharị eletriki nke myocardium, si otú ahụ belata ọnụ ọgụgụ ndị ọrịa nwere ọbara mgbali elu na-anwụ anwụ, ọ bụ ọgwụ kachasị dị irè maka ọgwụgwọ ọbara mgbali elu na ọrịa obi.