Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Dị Ọcha> Ụlọ ọrụ 99.0% (HPLC)

Nkọwa dị mkpirikpi:

Aha Chemical: 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride

Ihe atụ: Irbesartan Side Chain Hydrochloride

Nọmba: 151257-01-1

Dị ọcha:> 99.0% (HPLC)

Ọdịdị: Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ

Ọkara nke Irbesartan (CAS: 138402-11-6)

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Njirimara kemịkalụ:

Aha Chemical 2-Butyl-1,3-diazaspiro[4.4] na-abụghị 1-en-4-otu Hydrochloride
Ụdị okwu Irbesartan Side Chain Hydrochloride;Irbesartan Lactam adịghị ọcha;Irbesartan adịghị ọcha A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-otu Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4] na-abụghị 1-en-4-otu HCl
Nọmba CAS 151257-01-1
Nọmba CAT RF-PI1894
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C11H18N2O·HCl
Ibu molekụla 230.74
Solubility na Mmiri Soluble na Mmiri
Ebe Na-agbaze 235.0 ~ 240.0 ℃
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ
Ụzọ ịdị ọcha / nyocha > 99.0% (HPLC)
Ọnwụ na ihicha <0.50%
Ihe fọdụrụ na mgbanye <0.20%
Mgbakọta adịghị ọcha <1.00%
Ọnụ ego nke Proton NMR Spectrum Dabara na Ọdịdị
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ọkara nke Irbesartan (CAS: 138402-11-6)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

1

Ajụjụ:

Ngwa:

2-Butyl-1,3-diazaspiro[4.4] na-abụghị 1-en-4-otu Hydrochloride (CAS: 151257-01-1), makwaara dị ka Irbesartan Side Chain Hydrochloride, bụ Intermediate nke Irbesartan (Avapro) (CAS). : 138402-11-6).Irbesartan bụ angiotensin II receptor inhibitor, ndị na-anabata angiotensin II na-ekewa n'ime AT1, AT2, irbesartan nwere ike igbochi AngⅠtransform n'ime AngII site na-ahọpụtara igbochi AT1 receptor AngII, kpọmkwem na-emegide angiotensin na-agbanwe enzyme 1 receptor (AT1) nke antagonism. ugboro karịa nke AT2, ọ nwere ike igbochi vasoconstriction na ntọhapụ aldosterone site na ịhọrọ nke ọma igbochi AngII na-ejikọta ya na onye na-anabata AT1 ma mee ka mmetụta antihypertensive pụta.Ngwaahịa a anaghị egbochi angiotensin na-agbanwe enzyme (ACE), renin, na ndị na-anabata homonụ ndị ọzọ, anaghị egbochi usoro ọbara mgbali na nguzozi nke ọwa sodium ion.Irbesartan nwekwara ike ibelata mmezigharị eletriki nke myocardium, si otú ahụ belata ọnụ ọgụgụ ndị ọrịa nwere ọbara mgbali elu na-anwụ anwụ, ọ bụ ọgwụ kachasị dị irè maka ọgwụgwọ ọbara mgbali elu na ọrịa obi.

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