Ivabradine Hydrochloride CAS 148849-67-6 Ịdị Ọcha>99.5% (HPLC) Ụlọ ọrụ API
Ruifu Chemical Supply Ivabradine Hydrochloride Intermediates nwere ịdị ọcha dị elu
Ivabradine Hydrochloride CAS 148849-67-6
4,5-Dimethoxy-1-Cyanobenzocyclobutane CAS 35202-54-1
(1S) -4,5-Dimethoxy-1-[(methylamino)methyl] benzocyclobutane Hydrochloride CAS 866783-13-3
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-otu CAS 73942-87-7
7,8-Dimethoxy-3- (3-iodopropyl) -1,3-dihydro-2H-3-benzazepin-2-otu CAS 148870-57-9
3- (3-Chloropyl) -7,8-dimethoxy-1H-3-benzazepin-2 (3H) -otu CAS 85175-59-3
Aha Chemical | Ivabradine hydrochloride |
Ụdị okwu | Ivabradine HCl |
Nọmba CAS | 148849-67-6 |
Nọmba CAT | RF-PI1812 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C27H36N2O5·HCl |
Ibu molekụla | 505.05 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
njirimara | HPLC/UV na-akwado |
Ụzọ ịdị ọcha / nyocha | > 99.5% |
Ọnwụ na ihicha | <1.00% (Kọchaa ya na 105 ℃ na igwe ikuku eletrik na-afụ ọkụ ruo mgbe ịdị arọ) |
Ọdịnaya Ọdịnaya | <1.00% |
Ihe fọdụrụ na mgbanye | <0.20% |
Oke Otu adịghị ọcha | <0.50% |
Mgbakọta adịghị ọcha | <0.50% |
Ngwa anya Isomer | <0.50% |
Nyocha | > 99.5% |
Ọla dị arọ | <20ppm |
Ntụgharị akọwapụtara | +6.5° ~ +8.5° (na akpọnwụwo ndabere, 1% ngwọta na DMSO) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Ivabradine Hydrochloride (CAS: 148849-67-6),N'ịgbalị ịmepụta ndị na-ahụ maka angina na-enweghị mmetụta inotropic na-adịghị mma na hypotensive na-achọghị nke metụtara b-adrenergic blockers na calcium channel blockers, a chọpụtala klas ọhụrụ nke obi-ọnụọgụ na-ebelata ogige ndị na-eme kpọmkwem na ọnụ sinoatrial (SA).Ihe ndị a bradycardic na-emekọrịta ihe ozugbo na cell pacemaking nke oghere SA yana hyperpolarization na-arụ ọrụ ma ọ bụrụ na ọ bụ isi ihe na-eme ugbu a.Ivabradine etolitela dị ka onye na-egbochi ọ bụrụ na ọ dị ugbu a site na kọntaktị ya na f-channel n'akụkụ intracellular nke akpụkpọ ahụ plasma.N'ihi nke a, Ivabradine na-ebelata ọsọ nke depolarization diastolic ma na-ebelata ọnụ ọgụgụ obi.A kwadoro ya maka ọgwụgwọ angina kwụsiri ike na-adịghị ala ala ma na-enye ụzọ dị mma maka ndị ọrịa nwere mgbochi ma ọ bụ anabataghị b-blockers.A na-emekwa nyocha maka ọgwụgwọ nke ọrịa obi ischemic nwere ike ime.